Total number of protein in "GO:0001944" GO term: 35
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0001944 | Not Cancer Driver | No | 83 | 0.162 | 70 | 14 | 0.2 | 2 |
| ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0001944 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
| ANGPT1 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0001944 | Not Cancer Driver | No | 130 | 0.261 | 131 | 24 | 0.183 | 1 |
| ANGPT2 | ANGPT2 | O15123 | Angiopoietin-2 | chr8 | GO:0001944 | Not Cancer Driver | No | 63 | 0.127 | 96 | 10 | 0.104 | 1 |
| ANP32B | ANP32B | Q92688 | Acidic leucine-rich nuclear phosphoprotein 32 family member B | chr9 | GO:0001944 | Not Cancer Driver | No | 22 | 0.088 | 117 | 12 | 0.103 | 0 |
| APLNR | APLNR | P35414 | Apelin receptor | chr11 | GO:0001944 | Not Cancer Driver | No | 96 | 0.253 | 29 | 8 | 0.276 | 0 |
| B9D1 | B9D1 | Q9UPM9 | B9 domain-containing protein 1 | chr17 | GO:0001944 | Not Cancer Driver | No | 16 | 0.078 | 51 | 6 | 0.118 | 2 |
| BLOC1S6_ENST00000220531 | BLOC1S6 | Q9UL45 | Biogenesis of lysosome-related organelles complex 1 subunit 6 | chr15 | GO:0001944 | Not Cancer Driver | No | 12 | 0.07 | 111 | 11 | 0.099 | 0 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0001944 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0001944 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
| ERRFI1 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0001944 | Not Cancer Driver | No | 55 | 0.119 | 297 | 37 | 0.125 | 0 |
| FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0001944 | Census, Compendium | Yes | 322 | 0.455 | 230 | 38 | 0.165 | 0 |
| FLT4 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0001944 | Census, Compendium | Yes | 253 | 0.186 | 259 | 41 | 0.158 | 13 |
| FOXF1 | FOXF1 | Q12946 | Forkhead box protein F1 | chr16 | GO:0001944 | Not Cancer Driver | No | 56 | 0.148 | 194 | 20 | 0.103 | 20 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0001944 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0001944 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| IMMP2L_ENST00000452895 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | GO:0001944 | Not Cancer Driver | No | 36 | 0.206 | 29 | 7 | 0.241 | 0 |
| LIF | LIF | P15018 | Leukemia inhibitory factor | chr22 | GO:0001944 | Not Cancer Driver | No | 25 | 0.124 | 0 | 0 | 0.0 | 0 |
| NODAL | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0001944 | Not Cancer Driver | No | 40 | 0.115 | 34 | 8 | 0.235 | 4 |
| NOTCH4 | NOTCH4 | Q99466 | Neurogenic locus notch homolog protein 4 | chr6 | GO:0001944 | Not Cancer Driver | No | 336 | 0.168 | 464 | 79 | 0.17 | 0 |
| OSR1 | OSR1 | Q8TAX0 | Protein odd-skipped-related 1 | chr2 | GO:0001944 | Not Cancer Driver | No | 57 | 0.214 | 67 | 17 | 0.254 | 0 |
| PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0001944 | Census, Compendium | Yes | 290 | 0.266 | 173 | 45 | 0.26 | 2 |
| PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0001944 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0001944 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| RIC8A_ENST00000526104 | RIC8A | Q9NPQ8 | Synembryn-A | chr11 | GO:0001944 | Not Cancer Driver | No | 63 | 0.119 | 163 | 23 | 0.141 | 0 |
| ROM1 | ROM1 | Q03395 | Rod outer segment membrane protein 1 | chr11 | GO:0001944 | Not Cancer Driver | No | 41 | 0.117 | 26 | 4 | 0.154 | 0 |
| SOX18 | SOX18 | P35713 | Transcription factor SOX-18 | chr20 | GO:0001944 | Not Cancer Driver | No | 10 | 0.026 | 321 | 10 | 0.031 | 2 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0001944 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
| STRA6_ENST00000323940 | STRA6 | Q9BX79 | Receptor for retinol uptake STRA6 | chr15 | GO:0001944 | Not Cancer Driver | No | 77 | 0.115 | 84 | 14 | 0.167 | 6 |
| TCF21 | TCF21 | O43680 | Transcription factor 21 | chr6 | GO:0001944 | Not Cancer Driver | No | 55 | 0.307 | 120 | 40 | 0.333 | 0 |
| TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0001944 | Not Cancer Driver | No | 219 | 0.195 | 126 | 22 | 0.175 | 10 |
| TMEM231 | TMEM231 | Q9H6L2 | Transmembrane protein 231 | chr16 | GO:0001944 | Not Cancer Driver | No | 15 | 0.047 | 16 | 1 | 0.062 | 2 |
| UNC13D | UNC13D | Q70J99 | Protein unc-13 homolog D | chr17 | GO:0001944 | Not Cancer Driver | No | 120 | 0.11 | 248 | 30 | 0.121 | 0 |
| VSTM4 | VSTM4 | Q8IW00 | V-set and transmembrane domain-containing protein 4 | chr10 | GO:0001944 | Not Cancer Driver | No | 91 | 0.284 | 47 | 9 | 0.191 | 0 |
| ZFAND5 | ZFAND5 | O76080 | AN1-type zinc finger protein 5 | chr9 | GO:0001944 | Not Cancer Driver | No | 31 | 0.146 | 162 | 19 | 0.117 | 0 |