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Total number of protein in "GO:0001726" GO term:  94

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0001726 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 GO:0001726 Not Cancer Driver No 97 0.125 287 40 0.139 0
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 GO:0001726 Not Cancer Driver No 108 0.121 195 30 0.154 6
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0001726 Not Cancer Driver No 14 0.095 61 6 0.098 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0001726 Not Cancer Driver No 194 0.117 353 36 0.102 0
AMOT AMOT Q4VCS5 Angiomotin chrX GO:0001726 Not Cancer Driver No 161 0.149 909 128 0.141 0
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0001726 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0001726 Not Cancer Driver No 70 0.105 149 14 0.094 0
ARAP3 ARAP3 Q8WWN8 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 chr5 GO:0001726 Not Cancer Driver No 179 0.116 576 68 0.118 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0001726 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARFIP2_ENST00000254584 ARFIP2 P53365 Arfaptin-2 chr11 GO:0001726 Not Cancer Driver No 37 0.109 144 15 0.104 0
ARHGAP18 ARHGAP18 Q8N392 Rho GTPase-activating protein 18 chr6 GO:0001726 Not Cancer Driver No 87 0.131 297 39 0.131 0
ARHGEF26 ARHGEF26 Q96DR7 Rho guanine nucleotide exchange factor 26 chr3 GO:0001726 Not Cancer Driver No 164 0.188 475 86 0.181 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0001726 Not Cancer Driver No 106 0.132 301 39 0.13 0
ASAP3 ASAP3 Q8TDY4 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 chr1 GO:0001726 Not Cancer Driver No 99 0.11 389 48 0.123 0
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 GO:0001726 Not Cancer Driver No 63 0.123 49 4 0.082 1
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0001726 Not Cancer Driver No 85 0.154 330 52 0.158 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0001726 Not Cancer Driver No 108 0.124 677 75 0.111 0
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 GO:0001726 Not Cancer Driver No 45 0.129 95 7 0.074 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 GO:0001726 Not Cancer Driver No 154 0.107 669 75 0.112 4
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0001726 Not Cancer Driver No 80 0.125 456 60 0.132 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0001726 Census Yes 40 0.123 24 3 0.125 1
CLIP1 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0001726 Census, Compendium Yes 184 0.128 1194 136 0.114 0
COBL_ENST00000265136 COBL O75128 Protein cordon-bleu chr7 GO:0001726 Not Cancer Driver No 233 0.185 1149 216 0.188 0
CSPG4 CSPG4 Q6UVK1 Chondroitin sulfate proteoglycan 4 chr15 GO:0001726 Not Cancer Driver No 259 0.112 838 85 0.101 0
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 GO:0001726 Not Cancer Driver No 78 0.142 465 56 0.12 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0001726 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYTH3_ENST00000396741 CYTH3 O43739 Cytohesin-3 chr7 GO:0001726 Not Cancer Driver No 49 0.122 96 12 0.125 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0001726 Not Cancer Driver No 46 0.107 304 31 0.102 0
EZR EZR P15311 Ezrin chr6 GO:0001726 Census Yes 66 0.113 295 35 0.119 0
FGD1 FGD1 P98174 FYVE, RhoGEF and PH domain-containing protein 1 chrX GO:0001726 Not Cancer Driver No 139 0.145 520 74 0.142 5
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0001726 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGD3 FGD3 Q5JSP0 FYVE, RhoGEF and PH domain-containing protein 3 chr9 GO:0001726 Not Cancer Driver No 117 0.161 404 72 0.178 0
FGD4_ENST00000427716 FGD4 Q96M96 FYVE, RhoGEF and PH domain-containing protein 4 chr12 GO:0001726 Not Cancer Driver No 78 0.102 290 28 0.097 2
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 GO:0001726 Compendium Yes 275 0.188 915 180 0.197 0
FGD6 FGD6 Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 chr12 GO:0001726 Not Cancer Driver No 198 0.138 804 117 0.146 0
FRMD4B FRMD4B Q9Y2L6 FERM domain-containing protein 4B chr3 GO:0001726 Not Cancer Driver No 102 0.099 542 60 0.111 0
FSCN1 FSCN1 Q16658 Fascin chr7 GO:0001726 Not Cancer Driver No 58 0.118 81 5 0.062 0
FSCN3 FSCN3 Q9NQT6 Fascin-3 chr7 GO:0001726 Not Cancer Driver No 101 0.203 5 0 0.0 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:0001726 Not Cancer Driver No 43 0.067 272 16 0.059 15
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0001726 Not Cancer Driver No 102 0.101 629 42 0.067 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0001726 Not Cancer Driver No 42 0.094 34 2 0.059 7
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0001726 Not Cancer Driver No 183 0.11 351 35 0.1 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0001726 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0001726 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0001726 Not Cancer Driver No 103 0.129 84 10 0.119 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0001726 Not Cancer Driver No 114 0.127 405 60 0.148 0
KLHL2_ENST00000226725 KLHL2 O95198 Kelch-like protein 2 chr4 GO:0001726 Not Cancer Driver No 80 0.135 42 5 0.119 0
KLHL41 KLHL41 O60662 Kelch-like protein 41 chr2 GO:0001726 Not Cancer Driver No 69 0.114 18 2 0.111 1
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 GO:0001726 Census Yes 75 0.237 246 67 0.272 0
LAYN LAYN Q6UX15 Layilin chr11 GO:0001726 Not Cancer Driver No 59 0.154 116 21 0.181 0
LCP1 LCP1 P13796 Plastin-2 chr13 GO:0001726 Census Yes 99 0.158 73 11 0.151 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 GO:0001726 Not Cancer Driver No 88 0.116 687 81 0.118 0
MEFV MEFV O15553 Pyrin chr16 GO:0001726 Not Cancer Driver No 196 0.251 397 119 0.3 47
MKLN1 MKLN1 Q9UL63 Muskelin chr7 GO:0001726 Not Cancer Driver No 85 0.116 91 13 0.143 0
MTM1 MTM1 Q13496 Myotubularin chrX GO:0001726 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 GO:0001726 Not Cancer Driver No 58 0.089 150 8 0.053 2
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0001726 Not Cancer Driver No 107 0.142 584 86 0.147 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0001726 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0001726 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYO10 MYO10 Q9HD67 Unconventional myosin-X chr5 GO:0001726 Not Cancer Driver No 296 0.144 418 59 0.141 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0001726 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 GO:0001726 Census, Compendium Yes 224 0.121 497 58 0.117 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0001726 Not Cancer Driver No 176 0.136 342 41 0.12 3
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0001726 Not Cancer Driver No 129 0.114 44 3 0.068 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0001726 Not Cancer Driver No 13 0.086 11 1 0.091 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0001726 Not Cancer Driver No 57 0.105 299 30 0.1 2
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 GO:0001726 Not Cancer Driver No 25 0.072 177 13 0.073 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 GO:0001726 Not Cancer Driver No 48 0.105 244 20 0.082 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0001726 Not Cancer Driver No 37 0.228 96 24 0.25 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0001726 Census, Compendium Yes 158 0.122 186 21 0.113 0
PODXL PODXL O00592 Podocalyxin chr7 GO:0001726 Not Cancer Driver No 69 0.124 432 56 0.13 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0001726 Census Yes 42 0.093 12 0 0.0 0
RAB22A RAB22A Q9UL26 Ras-related protein Rab-22A chr20 GO:0001726 Not Cancer Driver No 23 0.119 23 4 0.174 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 GO:0001726 Not Cancer Driver No 32 0.149 65 15 0.231 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 GO:0001726 Compendium Yes 154 0.147 181 25 0.138 3
RINL RINL Q6ZS11 Ras and Rab interactor-like protein chr19 GO:0001726 Not Cancer Driver No 50 0.088 367 32 0.087 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0001726 Not Cancer Driver No 184 0.136 780 103 0.132 0
S100A11 S100A11 P31949 Protein S100-A11 chr1 GO:0001726 Not Cancer Driver No 13 0.124 14 2 0.143 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 GO:0001726 Not Cancer Driver No 5 0.056 4 0 0.0 0
S100B S100B P04271 Protein S100-B chr21 GO:0001726 Not Cancer Driver No 17 0.185 13 1 0.077 0
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 GO:0001726 Not Cancer Driver No 112 0.3 291 85 0.292 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0001726 Not Cancer Driver No 10 0.069 73 9 0.123 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0001726 Not Cancer Driver No 19 0.053 318 16 0.05 4
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0001726 Not Cancer Driver No 33 0.082 91 13 0.143 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 GO:0001726 Not Cancer Driver No 71 0.119 231 23 0.1 0
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0001726 Not Cancer Driver No 31 0.145 73 6 0.082 0
TLN1 TLN1 Q9Y490 Talin-1 chr9 GO:0001726 Not Cancer Driver No 278 0.109 1109 126 0.114 0
TLN2 TLN2 Q9Y4G6 Talin-2 chr15 GO:0001726 Not Cancer Driver No 336 0.132 892 123 0.138 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0001726 Not Cancer Driver No 292 0.348 0 0 0.0 0
TRPM7 TRPM7 Q96QT4 Transient receptor potential cation channel subfamily M member 7 chr15 GO:0001726 Not Cancer Driver No 199 0.107 455 60 0.132 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0001726 Not Cancer Driver No 124 0.15 222 38 0.171 0
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 GO:0001726 Not Cancer Driver No 61 0.122 400 43 0.107 0
WIPF1_ENST00000359761 WIPF1 O43516 WAS/WASL-interacting protein family member 1 chr2 GO:0001726 Not Cancer Driver No 110 0.219 503 110 0.219 0