Total number of protein in "GO:0001666" GO term: 152
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABAT_ENST00000268251 | ABAT | P80404 | 4-aminobutyrate aminotransferase, mitochondrial | chr16 | GO:0001666 | Not Cancer Driver | No | 84 | 0.168 | 28 | 5 | 0.179 | 1 |
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0001666 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | GO:0001666 | Not Cancer Driver | No | 131 | 0.144 | 244 | 42 | 0.172 | 8 |
| ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0001666 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
| ADA | ADA | P00813 | Adenosine deaminase | chr20 | GO:0001666 | Not Cancer Driver | No | 50 | 0.138 | 44 | 9 | 0.205 | 27 |
| ADAM15 | ADAM15 | Q13444 | Disintegrin and metalloproteinase domain-containing protein 15 | chr1 | GO:0001666 | Not Cancer Driver | No | 104 | 0.121 | 213 | 29 | 0.136 | 0 |
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0001666 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0001666 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
| ADM | ADM | P35318 | Pro-adrenomedullin | chr11 | GO:0001666 | Not Cancer Driver | No | 20 | 0.108 | 113 | 13 | 0.115 | 0 |
| ADORA1 | ADORA1 | P30542 | Adenosine receptor A1 | chr1 | GO:0001666 | Not Cancer Driver | No | 64 | 0.196 | 12 | 4 | 0.333 | 0 |
| ADSL | ADSL | P30566 | Adenylosuccinate lyase | chr22 | GO:0001666 | Not Cancer Driver | No | 68 | 0.14 | 36 | 9 | 0.25 | 27 |
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0001666 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AGTRAP | AGTRAP | Q6RW13 | Type-1 angiotensin II receptor-associated protein | chr1 | GO:0001666 | Not Cancer Driver | No | 20 | 0.126 | 11 | 0 | 0.0 | 0 |
| AJUBA | AJUBA | Q96IF1 | LIM domain-containing protein ajuba | chr14 | GO:0001666 | Compendium | Yes | 45 | 0.084 | 307 | 13 | 0.042 | 0 |
| ALAD | ALAD | P13716 | Delta-aminolevulinic acid dehydratase | chr9 | GO:0001666 | Not Cancer Driver | No | 52 | 0.158 | 13 | 3 | 0.231 | 5 |
| ALAS2 | ALAS2 | P22557 | 5-aminolevulinate synthase, erythroid-specific, mitochondrial | chrX | GO:0001666 | Not Cancer Driver | No | 107 | 0.182 | 87 | 17 | 0.195 | 24 |
| ALKBH5 | ALKBH5 | Q6P6C2 | RNA demethylase ALKBH5 | chr17 | GO:0001666 | Not Cancer Driver | No | 41 | 0.104 | 200 | 23 | 0.115 | 0 |
| ANG | ANG | P03950 | Angiogenin | chr14 | GO:0001666 | Not Cancer Driver | No | 19 | 0.129 | 36 | 2 | 0.056 | 14 |
| ANGPT2 | ANGPT2 | O15123 | Angiopoietin-2 | chr8 | GO:0001666 | Not Cancer Driver | No | 63 | 0.127 | 96 | 10 | 0.104 | 1 |
| ANGPTL4 | ANGPTL4 | Q9BY76 | Angiopoietin-related protein 4 | chr19 | GO:0001666 | Not Cancer Driver | No | 47 | 0.116 | 180 | 22 | 0.122 | 0 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0001666 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| ARNT | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | GO:0001666 | Census | Yes | 77 | 0.098 | 511 | 56 | 0.11 | 0 |
| ARNT2 | ARNT2 | Q9HBZ2 | Aryl hydrocarbon receptor nuclear translocator 2 | chr15 | GO:0001666 | Not Cancer Driver | No | 100 | 0.139 | 448 | 61 | 0.136 | 0 |
| ASCL2 | ASCL2 | Q99929 | Achaete-scute homolog 2 | chr11 | GO:0001666 | Not Cancer Driver | No | 2 | 0.01 | 166 | 1 | 0.006 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0001666 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| ATP1B1 | ATP1B1 | P05026 | Sodium/potassium-transporting ATPase subunit beta-1 | chr1 | GO:0001666 | Not Cancer Driver | No | 38 | 0.125 | 55 | 9 | 0.164 | 0 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0001666 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0001666 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0001666 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | GO:0001666 | Not Cancer Driver | No | 72 | 0.157 | 274 | 50 | 0.182 | 0 |
| CAPN2 | CAPN2 | P17655 | Calpain-2 catalytic subunit | chr1 | GO:0001666 | Not Cancer Driver | No | 81 | 0.116 | 46 | 11 | 0.239 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0001666 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CAT | CAT | P04040 | Catalase | chr11 | GO:0001666 | Not Cancer Driver | No | 70 | 0.133 | 176 | 18 | 0.102 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0001666 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0001666 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CBFA2T3 | CBFA2T3 | O75081 | Protein CBFA2T3 | chr16 | GO:0001666 | Census, Compendium | Yes | 83 | 0.127 | 502 | 70 | 0.139 | 0 |
| CD38 | CD38 | P28907 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | chr4 | GO:0001666 | Not Cancer Driver | No | 54 | 0.18 | 3 | 1 | 0.333 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0001666 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CHRNA4 | CHRNA4 | P43681 | Neuronal acetylcholine receptor subunit alpha-4 | chr20 | GO:0001666 | Not Cancer Driver | No | 144 | 0.23 | 186 | 33 | 0.177 | 2 |
| CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0001666 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
| CHRNB2 | CHRNB2 | P17787 | Neuronal acetylcholine receptor subunit beta-2 | chr1 | GO:0001666 | Not Cancer Driver | No | 92 | 0.183 | 23 | 2 | 0.087 | 2 |
| CIAO3 | CIAO3 | Q9H6Q4 | Cytosolic iron-sulfur assembly component 3 | chr16 | GO:0001666 | Not Cancer Driver | No | 49 | 0.103 | 68 | 4 | 0.059 | 0 |
| CITED2_ENST00000367651 | CITED2 | Q99967 | Cbp/p300-interacting transactivator 2 | chr6 | GO:0001666 | Not Cancer Driver | No | 23 | 0.085 | 230 | 18 | 0.078 | 0 |
| CLDN3 | CLDN3 | O15551 | Claudin-3 | chr7 | GO:0001666 | Not Cancer Driver | No | 12 | 0.055 | 0 | 0 | 0.0 | 0 |
| CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0001666 | Census, Compendium | Yes | 412 | 0.169 | 1796 | 247 | 0.138 | 33 |
| CRYAB_ENST00000616970 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | GO:0001666 | Not Cancer Driver | No | 22 | 0.126 | 59 | 11 | 0.186 | 4 |
| CXCL12_ENST00000374429 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:0001666 | Not Cancer Driver | No | 16 | 0.172 | 0 | 0 | 0.0 | 0 |
| CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | GO:0001666 | Census, Compendium | Yes | 62 | 0.176 | 5 | 1 | 0.2 | 0 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | GO:0001666 | Not Cancer Driver | No | 26 | 0.133 | 66 | 2 | 0.03 | 12 |
| CYGB | CYGB | Q8WWM9 | Cytoglobin | chr17 | GO:0001666 | Not Cancer Driver | No | 32 | 0.168 | 47 | 5 | 0.106 | 0 |
| CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0001666 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
| DDIT4 | DDIT4 | Q9NX09 | DNA damage-inducible transcript 4 protein | chr10 | GO:0001666 | Not Cancer Driver | No | 20 | 0.086 | 87 | 9 | 0.103 | 0 |
| DIO3 | DIO3 | P55073 | Thyroxine 5-deiodinase | chr14 | GO:0001666 | Not Cancer Driver | No | 88 | 0.289 | 71 | 18 | 0.254 | 0 |
| DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | GO:0001666 | Not Cancer Driver | No | 151 | 0.197 | 8 | 1 | 0.125 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0001666 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0001666 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| EGLN1 | EGLN1 | Q9GZT9 | Egl nine homolog 1 | chr1 | GO:0001666 | Not Cancer Driver | No | 35 | 0.082 | 206 | 8 | 0.039 | 2 |
| EGLN2_ENST00000303961 | EGLN2 | Q96KS0 | Prolyl hydroxylase EGLN2 | chr19 | GO:0001666 | Not Cancer Driver | No | 52 | 0.128 | 201 | 17 | 0.085 | 0 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | GO:0001666 | Not Cancer Driver | No | 33 | 0.138 | 13 | 0 | 0.0 | 0 |
| EGR1 | EGR1 | P18146 | Early growth response protein 1 | chr5 | GO:0001666 | Not Cancer Driver | No | 78 | 0.144 | 501 | 72 | 0.144 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0001666 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
| EPAS1 | EPAS1 | Q99814 | Endothelial PAS domain-containing protein 1 | chr2 | GO:0001666 | Census, Compendium | Yes | 120 | 0.138 | 449 | 53 | 0.118 | 6 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0001666 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| ERCC3 | ERCC3 | P19447 | General transcription and DNA repair factor IIH helicase subunit XPB | chr2 | GO:0001666 | Census, Compendium | Yes | 92 | 0.118 | 208 | 22 | 0.106 | 2 |
| F7 | F7 | P08709 | Coagulation factor VII | chr13 | GO:0001666 | Not Cancer Driver | No | 74 | 0.159 | 50 | 7 | 0.14 | 108 |
| FUNDC1 | FUNDC1 | Q8IVP5 | FUN14 domain-containing protein 1 | chrX | GO:0001666 | Not Cancer Driver | No | 16 | 0.103 | 24 | 2 | 0.083 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0001666 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| HIF3A | HIF3A | Q9Y2N7 | Hypoxia-inducible factor 3-alpha | chr19 | GO:0001666 | Not Cancer Driver | No | 146 | 0.218 | 361 | 94 | 0.26 | 0 |
| HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:0001666 | Not Cancer Driver | No | 138 | 0.15 | 77 | 7 | 0.091 | 0 |
| HMOX2_ENST00000406590 | HMOX2 | P30519 | Heme oxygenase 2 | chr16 | GO:0001666 | Not Cancer Driver | No | 27 | 0.085 | 74 | 10 | 0.135 | 0 |
| HSD11B2 | HSD11B2 | P80365 | 11-beta-hydroxysteroid dehydrogenase type 2 | chr16 | GO:0001666 | Not Cancer Driver | No | 27 | 0.067 | 30 | 0 | 0.0 | 14 |
| HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0001666 | Not Cancer Driver | No | 59 | 0.112 | 335 | 37 | 0.11 | 0 |
| HSP90B1 | HSP90B1 | P14625 | Endoplasmin | chr12 | GO:0001666 | Not Cancer Driver | No | 94 | 0.117 | 268 | 35 | 0.131 | 0 |
| IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0001666 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
| ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0001666 | Not Cancer Driver | No | 166 | 0.141 | 26 | 0 | 0.0 | 0 |
| ITPR1_ENST00000354582 | ITPR1 | Q14643 | Inositol 1,4,5-trisphosphate receptor type 1 | chr3 | GO:0001666 | Not Cancer Driver | No | 390 | 0.141 | 581 | 76 | 0.131 | 6 |
| ITPR2 | ITPR2 | Q14571 | Inositol 1,4,5-trisphosphate receptor type 2 | chr12 | GO:0001666 | Not Cancer Driver | No | 359 | 0.133 | 394 | 57 | 0.145 | 1 |
| KCNA5 | KCNA5 | P22460 | Potassium voltage-gated channel subfamily A member 5 | chr12 | GO:0001666 | Not Cancer Driver | No | 213 | 0.347 | 218 | 53 | 0.243 | 0 |
| KCNMA1 | KCNMA1 | Q12791 | Calcium-activated potassium channel subunit alpha-1 | chr10 | GO:0001666 | Not Cancer Driver | No | 222 | 0.18 | 225 | 39 | 0.173 | 5 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0001666 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LIMD1 | LIMD1 | Q9UGP4 | LIM domain-containing protein 1 | chr3 | GO:0001666 | Not Cancer Driver | No | 58 | 0.086 | 428 | 36 | 0.084 | 0 |
| LONP1 | LONP1 | P36776 | Lon protease homolog, mitochondrial | chr19 | GO:0001666 | Not Cancer Driver | No | 99 | 0.103 | 175 | 15 | 0.086 | 10 |
| LOXL2 | LOXL2 | Q9Y4K0 | Lysyl oxidase homolog 2 | chr8 | GO:0001666 | Not Cancer Driver | No | 134 | 0.173 | 39 | 4 | 0.103 | 0 |
| LTA | LTA | P01374 | Lymphotoxin-alpha | chr6 | GO:0001666 | Not Cancer Driver | No | 37 | 0.18 | 20 | 5 | 0.25 | 0 |
| MB_ENST00000397328 | MB | P02144 | Myoglobin | chr22 | GO:0001666 | Not Cancer Driver | No | 13 | 0.084 | 38 | 4 | 0.105 | 0 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0001666 | Not Cancer Driver | No | 75 | 0.154 | 483 | 74 | 0.153 | 46 |
| MMP14 | MMP14 | P50281 | Matrix metalloproteinase-14 | chr14 | GO:0001666 | Not Cancer Driver | No | 64 | 0.11 | 118 | 11 | 0.093 | 1 |
| MMP2 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0001666 | Not Cancer Driver | No | 123 | 0.186 | 29 | 6 | 0.207 | 2 |
| MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0001666 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
| MTHFR_ENST00000376590 | MTHFR | P42898 | Methylenetetrahydrofolate reductase | chr1 | GO:0001666 | Not Cancer Driver | No | 95 | 0.145 | 125 | 22 | 0.176 | 53 |
| MYOCD_ENST00000343344 | MYOCD | Q8IZQ8 | Myocardin | chr17 | GO:0001666 | Not Cancer Driver | No | 284 | 0.303 | 853 | 263 | 0.308 | 0 |
| NF1 | NF1 | P21359 | Neurofibromin | chr17 | GO:0001666 | Census, Compendium | Yes | 375 | 0.132 | 406 | 47 | 0.116 | 85 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0001666 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| NOS1_ENST00000317775 | NOS1 | P29475 | Nitric oxide synthase, brain | chr12 | GO:0001666 | Not Cancer Driver | No | 405 | 0.282 | 342 | 99 | 0.289 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | GO:0001666 | Not Cancer Driver | No | 207 | 0.18 | 201 | 33 | 0.164 | 0 |
| NPPC | NPPC | P23582 | C-type natriuretic peptide | chr2 | GO:0001666 | Not Cancer Driver | No | 10 | 0.079 | 82 | 6 | 0.073 | 0 |
| NR4A2_ENST00000409572 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0001666 | Not Cancer Driver | No | 110 | 0.184 | 261 | 38 | 0.146 | 0 |
| P2RX2_ENST00000643471 | P2RX2 | Q9UBL9 | P2X purinoceptor 2 | chr12 | GO:0001666 | Not Cancer Driver | No | 62 | 0.132 | 104 | 13 | 0.125 | 2 |
| P2RX3 | P2RX3 | P56373 | P2X purinoceptor 3 | chr11 | GO:0001666 | Not Cancer Driver | No | 85 | 0.214 | 15 | 6 | 0.4 | 0 |
| PAM_ENST00000438793 | PAM | P19021 | Peptidyl-glycine alpha-amidating monooxygenase | chr5 | GO:0001666 | Not Cancer Driver | No | 129 | 0.133 | 254 | 37 | 0.146 | 0 |
| PDGFA | PDGFA | P04085 | Platelet-derived growth factor subunit A | chr7 | GO:0001666 | Not Cancer Driver | No | 31 | 0.147 | 75 | 10 | 0.133 | 0 |
| PDLIM1 | PDLIM1 | O00151 | PDZ and LIM domain protein 1 | chr10 | GO:0001666 | Not Cancer Driver | No | 62 | 0.188 | 219 | 39 | 0.178 | 0 |
| PENK_ENST00000451791 | PENK | P01210 | Proenkephalin-A | chr8 | GO:0001666 | Not Cancer Driver | No | 109 | 0.408 | 142 | 62 | 0.437 | 0 |
| PGF_ENST00000405431 | PGF | P49763 | Placenta growth factor | chr14 | GO:0001666 | Not Cancer Driver | No | 30 | 0.136 | 72 | 10 | 0.139 | 0 |
| PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | GO:0001666 | Not Cancer Driver | No | 17 | 0.104 | 115 | 12 | 0.104 | 0 |
| PKLR | PKLR | P30613 | Pyruvate kinase PKLR | chr1 | GO:0001666 | Not Cancer Driver | No | 112 | 0.195 | 26 | 5 | 0.192 | 101 |
| PLAT | PLAT | P00750 | Tissue-type plasminogen activator | chr8 | GO:0001666 | Not Cancer Driver | No | 89 | 0.158 | 15 | 2 | 0.133 | 0 |
| PLAU | PLAU | P00749 | Urokinase-type plasminogen activator | chr10 | GO:0001666 | Not Cancer Driver | No | 59 | 0.137 | 10 | 0 | 0.0 | 0 |
| PLEKHN1 | PLEKHN1 | Q494U1 | Pleckstrin homology domain-containing family N member 1 | chr1 | GO:0001666 | Not Cancer Driver | No | 59 | 0.097 | 369 | 37 | 0.1 | 0 |
| PLOD1 | PLOD1 | Q02809 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | chr1 | GO:0001666 | Not Cancer Driver | No | 86 | 0.118 | 12 | 0 | 0.0 | 5 |
| PLOD2_ENST00000360060 | PLOD2 | O00469 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | chr3 | GO:0001666 | Not Cancer Driver | No | 109 | 0.148 | 17 | 3 | 0.176 | 4 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0001666 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PPARA_ENST00000402126 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | GO:0001666 | Not Cancer Driver | No | 63 | 0.135 | 68 | 9 | 0.132 | 0 |
| PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0001666 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0001666 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| REST | REST | Q13127 | RE1-silencing transcription factor | chr4 | GO:0001666 | Not Cancer Driver | No | 142 | 0.129 | 868 | 113 | 0.13 | 4 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0001666 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RYR1 | RYR1 | P21817 | Ryanodine receptor 1 | chr19 | GO:0001666 | Not Cancer Driver | No | 1003 | 0.199 | 1186 | 233 | 0.196 | 154 |
| RYR2 | RYR2 | Q92736 | Ryanodine receptor 2 | chr1 | GO:0001666 | Not Cancer Driver | No | 1703 | 0.343 | 782 | 281 | 0.359 | 51 |
| SCAP | SCAP | Q12770 | Sterol regulatory element-binding protein cleavage-activating protein | chr3 | GO:0001666 | Not Cancer Driver | No | 145 | 0.113 | 329 | 36 | 0.109 | 0 |
| SCFD1 | SCFD1 | Q8WVM8 | Sec1 family domain-containing protein 1 | chr14 | GO:0001666 | Not Cancer Driver | No | 66 | 0.103 | 117 | 12 | 0.103 | 0 |
| SLC11A2_ENST00000262051 | SLC11A2 | P49281 | Natural resistance-associated macrophage protein 2 | chr12 | GO:0001666 | Not Cancer Driver | No | 60 | 0.106 | 38 | 5 | 0.132 | 3 |
| SLC2A1 | SLC2A1 | P11166 | Solute carrier family 2, facilitated glucose transporter member 1 | chr1 | GO:0001666 | Not Cancer Driver | No | 51 | 0.104 | 13 | 2 | 0.154 | 48 |
| SLC2A8 | SLC2A8 | Q9NY64 | Solute carrier family 2, facilitated glucose transporter member 8 | chr9 | GO:0001666 | Not Cancer Driver | No | 28 | 0.059 | 19 | 0 | 0.0 | 0 |
| SLC6A4_ENST00000401766 | SLC6A4 | P31645 | Sodium-dependent serotonin transporter | chr17 | GO:0001666 | Not Cancer Driver | No | 101 | 0.16 | 73 | 12 | 0.164 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0001666 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0001666 | Census, Compendium | Yes | 198 | 0.359 | 195 | 17 | 0.087 | 8 |
| SOD2_ENST00000367055 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0001666 | Not Cancer Driver | No | 32 | 0.144 | 25 | 5 | 0.2 | 0 |
| SOD3 | SOD3 | P08294 | Extracellular superoxide dismutase [Cu-Zn] | chr4 | GO:0001666 | Not Cancer Driver | No | 22 | 0.092 | 123 | 14 | 0.114 | 0 |
| SRF | SRF | P11831 | Serum response factor | chr6 | GO:0001666 | Not Cancer Driver | No | 44 | 0.087 | 443 | 42 | 0.095 | 0 |
| TFRC_ENST00000392396 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | GO:0001666 | Census | Yes | 89 | 0.117 | 80 | 6 | 0.075 | 1 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0001666 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TGFB3 | TGFB3 | P10600 | Transforming growth factor beta-3 proprotein | chr14 | GO:0001666 | Not Cancer Driver | No | 45 | 0.109 | 96 | 14 | 0.146 | 1 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0001666 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| TGFBR3_ENST00000525962 | TGFBR3 | Q03167 | Transforming growth factor beta receptor type 3 | chr1 | GO:0001666 | Not Cancer Driver | No | 129 | 0.152 | 268 | 41 | 0.153 | 0 |
| TH | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0001666 | Not Cancer Driver | No | 61 | 0.116 | 149 | 21 | 0.141 | 38 |
| THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0001666 | Not Cancer Driver | No | 188 | 0.161 | 320 | 58 | 0.181 | 0 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0001666 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TM9SF4 | TM9SF4 | Q92544 | Transmembrane 9 superfamily member 4 | chr20 | GO:0001666 | Not Cancer Driver | No | 76 | 0.118 | 39 | 4 | 0.103 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0001666 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TXN2_ENST00000403313 | TXN2 | Q99757 | Thioredoxin, mitochondrial | chr22 | GO:0001666 | Not Cancer Driver | No | 22 | 0.133 | 34 | 4 | 0.118 | 0 |
| UCP2 | UCP2 | P55851 | Mitochondrial uncoupling protein 2 | chr11 | GO:0001666 | Not Cancer Driver | No | 31 | 0.1 | 11 | 3 | 0.273 | 0 |
| UCP3 | UCP3 | P55916 | Mitochondrial uncoupling protein 3 | chr11 | GO:0001666 | Not Cancer Driver | No | 37 | 0.119 | 7 | 1 | 0.143 | 1 |
| USF1 | USF1 | P22415 | Upstream stimulatory factor 1 | chr1 | GO:0001666 | Not Cancer Driver | No | 52 | 0.168 | 271 | 44 | 0.162 | 0 |
| VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | GO:0001666 | Not Cancer Driver | No | 188 | 0.254 | 110 | 28 | 0.255 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0001666 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| VEGFB | VEGFB | P49765 | Vascular endothelial growth factor B | chr11 | GO:0001666 | Not Cancer Driver | No | 25 | 0.121 | 125 | 22 | 0.176 | 0 |
| VEGFC | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0001666 | Not Cancer Driver | No | 128 | 0.305 | 37 | 12 | 0.324 | 0 |
| VEGFD | VEGFD | O43915 | Vascular endothelial growth factor D | chrX | GO:0001666 | Not Cancer Driver | No | 59 | 0.167 | 33 | 6 | 0.182 | 0 |
| WDR83 | WDR83 | Q9BRX9 | WD repeat domain-containing protein 83 | chr19 | GO:0001666 | Not Cancer Driver | No | 28 | 0.089 | 35 | 3 | 0.086 | 0 |
| WTIP | WTIP | A6NIX2 | Wilms tumor protein 1-interacting protein | chr19 | GO:0001666 | Not Cancer Driver | No | 32 | 0.074 | 217 | 2 | 0.009 | 0 |
| XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0001666 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |