Total number of protein in "GO:0001540" GO term: 84
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACHE_ENST00000241069 | ACHE | P22303 | Acetylcholinesterase | chr7 | GO:0001540 | Not Cancer Driver | No | 81 | 0.132 | 64 | 8 | 0.125 | 0 |
| ADRB2 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | GO:0001540 | Not Cancer Driver | No | 52 | 0.126 | 35 | 4 | 0.114 | 0 |
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0001540 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| APBA1 | APBA1 | Q02410 | Amyloid-beta A4 precursor protein-binding family A member 1 | chr9 | GO:0001540 | Not Cancer Driver | No | 149 | 0.178 | 556 | 103 | 0.185 | 0 |
| APBA2_ENST00000561069 | APBA2 | Q99767 | Amyloid-beta A4 precursor protein-binding family A member 2 | chr15 | GO:0001540 | Not Cancer Driver | No | 184 | 0.246 | 429 | 117 | 0.273 | 0 |
| APBA3 | APBA3 | O96018 | Amyloid-beta A4 precursor protein-binding family A member 3 | chr19 | GO:0001540 | Not Cancer Driver | No | 55 | 0.096 | 306 | 43 | 0.141 | 0 |
| APBB1 | APBB1 | O00213 | Amyloid beta precursor protein binding family B member 1 | chr11 | GO:0001540 | Not Cancer Driver | No | 105 | 0.148 | 399 | 58 | 0.145 | 0 |
| APBB2_ENST00000295974 | APBB2 | Q92870 | Amyloid beta precursor protein binding family B member 2 | chr4 | GO:0001540 | Not Cancer Driver | No | 88 | 0.116 | 419 | 51 | 0.122 | 0 |
| APBB3_ENST00000357560 | APBB3 | O95704 | Amyloid-beta A4 precursor protein-binding family B member 3 | chr5 | GO:0001540 | Not Cancer Driver | No | 64 | 0.132 | 102 | 13 | 0.127 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0001540 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
| APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0001540 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
| ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | GO:0001540 | Not Cancer Driver | No | 200 | 0.197 | 115 | 29 | 0.252 | 31 |
| BACE1 | BACE1 | P56817 | Beta-secretase 1 | chr11 | GO:0001540 | Not Cancer Driver | No | 55 | 0.11 | 53 | 5 | 0.094 | 0 |
| BCHE | BCHE | P06276 | Cholinesterase | chr3 | GO:0001540 | Not Cancer Driver | No | 185 | 0.307 | 14 | 4 | 0.286 | 38 |
| C1QA | C1QA | P02745 | Complement C1q subcomponent subunit A | chr1 | GO:0001540 | Not Cancer Driver | No | 41 | 0.167 | 124 | 16 | 0.129 | 0 |
| CACNA1A_ENST00000360228 | CACNA1A | O00555 | Voltage-dependent P/Q-type calcium channel subunit alpha-1A | chr19 | GO:0001540 | Not Cancer Driver | No | 436 | 0.174 | 1144 | 132 | 0.115 | 46 |
| CACNA1B | CACNA1B | Q00975 | Voltage-dependent N-type calcium channel subunit alpha-1B | chr9 | GO:0001540 | Not Cancer Driver | No | 416 | 0.178 | 917 | 115 | 0.125 | 0 |
| CALCR_ENST00000394441 | CALCR | P30988 | Calcitonin receptor | chr7 | GO:0001540 | Not Cancer Driver | No | 162 | 0.342 | 29 | 9 | 0.31 | 0 |
| CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0001540 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
| CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0001540 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
| CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0001540 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
| CLSTN1 | CLSTN1 | O94985 | Calsyntenin-1 | chr1 | GO:0001540 | Not Cancer Driver | No | 110 | 0.112 | 271 | 22 | 0.081 | 0 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | GO:0001540 | Not Cancer Driver | No | 69 | 0.154 | 156 | 27 | 0.173 | 0 |
| COL25A1 | COL25A1 | Q9BXS0 | Collagen alpha-1(XXV) chain | chr4 | GO:0001540 | Not Cancer Driver | No | 148 | 0.226 | 622 | 144 | 0.232 | 1 |
| CRYAB_ENST00000616970 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | GO:0001540 | Not Cancer Driver | No | 22 | 0.126 | 59 | 11 | 0.186 | 4 |
| CST3_ENST00000376925 | CST3 | P01034 | Cystatin-C | chr20 | GO:0001540 | Not Cancer Driver | No | 17 | 0.116 | 31 | 1 | 0.032 | 2 |
| DLGAP3 | DLGAP3 | O95886 | Disks large-associated protein 3 | chr1 | GO:0001540 | Not Cancer Driver | No | 156 | 0.159 | 810 | 131 | 0.162 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0001540 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0001540 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| FBXO2 | FBXO2 | Q9UK22 | F-box only protein 2 | chr1 | GO:0001540 | Not Cancer Driver | No | 21 | 0.071 | 75 | 1 | 0.013 | 0 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0001540 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FPR2 | FPR2 | P25090 | N-formyl peptide receptor 2 | chr19 | GO:0001540 | Not Cancer Driver | No | 96 | 0.274 | 26 | 5 | 0.192 | 0 |
| FZD4 | FZD4 | Q9ULV1 | Frizzled-4 | chr11 | GO:0001540 | Not Cancer Driver | No | 57 | 0.106 | 33 | 5 | 0.152 | 19 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0001540 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| FZD6 | FZD6 | O60353 | Frizzled-6 | chr8 | GO:0001540 | Not Cancer Driver | No | 95 | 0.135 | 172 | 15 | 0.087 | 1 |
| GRIA1_ENST00000285900 | GRIA1 | P42261 | Glutamate receptor 1 | chr5 | GO:0001540 | Not Cancer Driver | No | 303 | 0.334 | 104 | 45 | 0.433 | 0 |
| GRIA2_ENST00000264426 | GRIA2 | P42262 | Glutamate receptor 2 | chr4 | GO:0001540 | Not Cancer Driver | No | 290 | 0.328 | 50 | 16 | 0.32 | 14 |
| GRIA3 | GRIA3 | P42263 | Glutamate receptor 3 | chrX | GO:0001540 | Not Cancer Driver | No | 209 | 0.234 | 56 | 15 | 0.268 | 4 |
| GRIA4_ENST00000530497 | GRIA4 | P48058 | Glutamate receptor 4 | chr11 | GO:0001540 | Not Cancer Driver | No | 227 | 0.252 | 63 | 25 | 0.397 | 4 |
| GRIN1_ENST00000371561 | GRIN1 | Q05586 | Glutamate receptor ionotropic, NMDA 1 | chr9 | GO:0001540 | Not Cancer Driver | No | 88 | 0.094 | 190 | 15 | 0.079 | 13 |
| GRIN2A_ENST00000330684 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0001540 | Census, Compendium | Yes | 528 | 0.361 | 506 | 207 | 0.409 | 31 |
| GRIN2B | GRIN2B | Q13224 | Glutamate receptor ionotropic, NMDA 2B | chr12 | GO:0001540 | Not Cancer Driver | No | 413 | 0.278 | 426 | 147 | 0.345 | 11 |
| GSAP | GSAP | A4D1B5 | Gamma-secretase-activating protein | chr7 | GO:0001540 | Not Cancer Driver | No | 89 | 0.104 | 13 | 0 | 0.0 | 0 |
| HSPG2 | HSPG2 | P98160 | Basement membrane-specific heparan sulfate proteoglycan core protein | chr1 | GO:0001540 | Compendium | Yes | 506 | 0.115 | 1709 | 194 | 0.114 | 1 |
| IAPP_ENST00000539393 | IAPP | P10997 | Islet amyloid polypeptide | chr12 | GO:0001540 | Not Cancer Driver | No | 22 | 0.247 | 10 | 2 | 0.2 | 0 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0001540 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0001540 | Not Cancer Driver | No | 166 | 0.141 | 26 | 0 | 0.0 | 0 |
| ITGAM_ENST00000287497 | ITGAM | P11215 | Integrin alpha-M | chr16 | GO:0001540 | Not Cancer Driver | No | 191 | 0.166 | 133 | 12 | 0.09 | 0 |
| ITGB2_ENST00000355153 | ITGB2 | P05107 | Integrin beta-2 | chr21 | GO:0001540 | Not Cancer Driver | No | 147 | 0.191 | 59 | 9 | 0.153 | 15 |
| ITM2A | ITM2A | O43736 | Integral membrane protein 2A | chrX | GO:0001540 | Not Cancer Driver | No | 75 | 0.285 | 26 | 9 | 0.346 | 0 |
| ITM2B | ITM2B | Q9Y287 | Integral membrane protein 2B | chr13 | GO:0001540 | Not Cancer Driver | No | 21 | 0.079 | 12 | 0 | 0.0 | 1 |
| ITM2C | ITM2C | Q9NQX7 | Integral membrane protein 2C | chr2 | GO:0001540 | Not Cancer Driver | No | 31 | 0.116 | 33 | 4 | 0.121 | 0 |
| KIR3DL1 | KIR3DL1 | P43629 | Killer cell immunoglobulin-like receptor 3DL1 | chr19 | GO:0001540 | Not Cancer Driver | No | 124 | 0.279 | 184 | 48 | 0.261 | 0 |
| LDLR | LDLR | P01130 | Low-density lipoprotein receptor | chr19 | GO:0001540 | Not Cancer Driver | No | 119 | 0.138 | 63 | 3 | 0.048 | 104 |
| LDLRAD3 | LDLRAD3 | Q86YD5 | Low-density lipoprotein receptor class A domain-containing protein 3 | chr11 | GO:0001540 | Not Cancer Driver | No | 46 | 0.133 | 123 | 14 | 0.114 | 0 |
| LDLRAP1 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0001540 | Not Cancer Driver | No | 36 | 0.117 | 119 | 17 | 0.143 | 1 |
| LILRB1_ENST00000396331 | LILRB1 | Q8NHL6 | Leukocyte immunoglobulin-like receptor subfamily B member 1 | chr19 | GO:0001540 | Not Cancer Driver | No | 203 | 0.312 | 291 | 97 | 0.333 | 0 |
| LILRB2_ENST00000314446 | LILRB2 | Q8N423 | Leukocyte immunoglobulin-like receptor subfamily B member 2 | chr19 | GO:0001540 | Not Cancer Driver | No | 148 | 0.248 | 235 | 50 | 0.213 | 0 |
| LRP1 | LRP1 | Q07954 | Prolow-density lipoprotein receptor-related protein 1 | chr12 | GO:0001540 | Not Cancer Driver | No | 664 | 0.146 | 317 | 52 | 0.164 | 1 |
| LRP8 | LRP8 | Q14114 | Low-density lipoprotein receptor-related protein 8 | chr1 | GO:0001540 | Not Cancer Driver | No | 94 | 0.098 | 190 | 24 | 0.126 | 0 |
| LRPAP1 | LRPAP1 | P30533 | Alpha-2-macroglobulin receptor-associated protein | chr4 | GO:0001540 | Not Cancer Driver | No | 41 | 0.115 | 188 | 20 | 0.106 | 0 |
| MAPK8IP2 | MAPK8IP2 | Q13387 | C-Jun-amino-terminal kinase-interacting protein 2 | chr22 | GO:0001540 | Not Cancer Driver | No | 49 | 0.059 | 568 | 27 | 0.048 | 0 |
| MARCO | MARCO | Q9UEW3 | Macrophage receptor MARCO | chr2 | GO:0001540 | Not Cancer Driver | No | 180 | 0.346 | 323 | 125 | 0.387 | 0 |
| MSR1 | MSR1 | P21757 | Macrophage scavenger receptor types I and II | chr8 | GO:0001540 | Not Cancer Driver | No | 167 | 0.37 | 241 | 106 | 0.44 | 0 |
| NGFR | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | GO:0001540 | Not Cancer Driver | No | 57 | 0.133 | 172 | 25 | 0.145 | 0 |
| NLGN1_ENST00000361589 | NLGN1 | Q8N2Q7 | Neuroligin-1 | chr3 | GO:0001540 | Not Cancer Driver | No | 214 | 0.248 | 248 | 61 | 0.246 | 4 |
| PFDN1 | PFDN1 | O60925 | Prefoldin subunit 1 | chr5 | GO:0001540 | Not Cancer Driver | No | 8 | 0.066 | 42 | 4 | 0.095 | 0 |
| PFDN2 | PFDN2 | Q9UHV9 | Prefoldin subunit 2 | chr1 | GO:0001540 | Not Cancer Driver | No | 18 | 0.117 | 111 | 11 | 0.099 | 0 |
| PFDN4 | PFDN4 | Q9NQP4 | Prefoldin subunit 4 | chr20 | GO:0001540 | Not Cancer Driver | No | 22 | 0.164 | 40 | 6 | 0.15 | 0 |
| PFDN5 | PFDN5 | Q99471 | Prefoldin subunit 5 | chr12 | GO:0001540 | Not Cancer Driver | No | 18 | 0.117 | 3 | 0 | 0.0 | 0 |
| PFDN6_ENST00000374610 | PFDN6 | O15212 | Prefoldin subunit 6 | chr6 | GO:0001540 | Not Cancer Driver | No | 14 | 0.109 | 57 | 8 | 0.14 | 0 |
| PGRMC1 | PGRMC1 | O00264 | Membrane-associated progesterone receptor component 1 | chrX | GO:0001540 | Not Cancer Driver | No | 30 | 0.154 | 74 | 16 | 0.216 | 0 |
| PICALM | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0001540 | Census | Yes | 89 | 0.137 | 320 | 42 | 0.131 | 0 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | GO:0001540 | Not Cancer Driver | No | 36 | 0.142 | 115 | 7 | 0.061 | 18 |
| RAMP3 | RAMP3 | O60896 | Receptor activity-modifying protein 3 | chr7 | GO:0001540 | Not Cancer Driver | No | 30 | 0.203 | 0 | 0 | 0.0 | 0 |
| SCARB1_ENST00000415380 | SCARB1 | Q8WTV0 | Scavenger receptor class B member 1 | chr12 | GO:0001540 | Not Cancer Driver | No | 53 | 0.096 | 6 | 1 | 0.167 | 0 |
| SORL1 | SORL1 | Q92673 | Sortilin-related receptor | chr11 | GO:0001540 | Not Cancer Driver | No | 374 | 0.169 | 87 | 10 | 0.115 | 0 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0001540 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0001540 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0001540 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TLR6 | TLR6 | Q9Y2C9 | Toll-like receptor 6 | chr4 | GO:0001540 | Not Cancer Driver | No | 99 | 0.124 | 1 | 0 | 0.0 | 0 |
| TM2D1_ENST00000294613 | TM2D1 | Q9BX74 | TM2 domain-containing protein 1 | chr1 | GO:0001540 | Not Cancer Driver | No | 28 | 0.135 | 11 | 5 | 0.455 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0001540 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| VBP1 | VBP1 | P61758 | Prefoldin subunit 3 | chrX | GO:0001540 | Not Cancer Driver | No | 27 | 0.137 | 47 | 7 | 0.149 | 0 |