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Total number of protein in "GO:0001525" GO term:  253

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAMP_ENST00000248450 AAMP Q13685 Angio-associated migratory cell protein chr2 GO:0001525 Not Cancer Driver No 31 0.071 126 10 0.079 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0001525 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:0001525 Census, Compendium Yes 78 0.215 0 0 0.0 1
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0001525 Not Cancer Driver No 73 0.195 42 10 0.238 16
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0001525 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0001525 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0001525 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0001525 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADIPOR2 ADIPOR2 Q86V24 Adiponectin receptor protein 2 chr12 GO:0001525 Not Cancer Driver No 44 0.114 82 7 0.085 0
ADM2_ENST00000395737 ADM2 Q7Z4H4 Protein ADM2 chr22 GO:0001525 Not Cancer Driver No 14 0.095 113 11 0.097 0
AGGF1 AGGF1 Q8N302 Angiogenic factor with G patch and FHA domains 1 chr5 GO:0001525 Not Cancer Driver No 100 0.14 582 80 0.137 1
AIMP1_ENST00000442366 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 GO:0001525 Not Cancer Driver No 31 0.099 161 19 0.118 0
AMOT AMOT Q4VCS5 Angiomotin chrX GO:0001525 Not Cancer Driver No 161 0.149 909 128 0.141 0
AMOTL1 AMOTL1 Q8IY63 Angiomotin-like protein 1 chr11 GO:0001525 Not Cancer Driver No 136 0.142 851 121 0.142 0
AMOTL2_ENST00000422605 AMOTL2 Q9Y2J4 Angiomotin-like protein 2 chr3 GO:0001525 Not Cancer Driver No 94 0.121 741 93 0.126 0
ANG ANG P03950 Angiogenin chr14 GO:0001525 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0001525 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0001525 Not Cancer Driver No 63 0.127 96 10 0.104 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0001525 Not Cancer Driver No 104 0.207 150 32 0.213 0
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0001525 Not Cancer Driver No 52 0.113 154 26 0.169 0
ANGPTL4 ANGPTL4 Q9BY76 Angiopoietin-related protein 4 chr19 GO:0001525 Not Cancer Driver No 47 0.116 180 22 0.122 0
ANGPTL6 ANGPTL6 Q8NI99 Angiopoietin-related protein 6 chr19 GO:0001525 Not Cancer Driver No 37 0.079 162 10 0.062 0
ANPEP ANPEP P15144 Aminopeptidase N chr15 GO:0001525 Not Cancer Driver No 175 0.181 109 26 0.239 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0001525 Not Cancer Driver No 49 0.145 20 4 0.2 0
APELA APELA P0DMC3 Apelin receptor early endogenous ligand chr4 GO:0001525 Not Cancer Driver No 1 0.019 0 0 0.0 0
APLN APLN Q9ULZ1 Apelin chrX GO:0001525 Not Cancer Driver No 8 0.104 51 6 0.118 0
APLNR APLNR P35414 Apelin receptor chr11 GO:0001525 Not Cancer Driver No 96 0.253 29 8 0.276 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0001525 Not Cancer Driver No 34 0.18 13 2 0.154 0
APOLD1 APOLD1 Q96LR9 Apolipoprotein L domain-containing protein 1 chr12 GO:0001525 Not Cancer Driver No 23 0.082 22 0 0.0 0
ARHGAP22_ENST00000249601 ARHGAP22 Q7Z5H3 Rho GTPase-activating protein 22 chr10 GO:0001525 Not Cancer Driver No 138 0.198 449 90 0.2 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:0001525 Not Cancer Driver No 103 0.138 482 67 0.139 0
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0001525 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 GO:0001525 Not Cancer Driver No 8 0.075 85 7 0.082 0
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0001525 Not Cancer Driver No 38 0.095 129 13 0.101 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0001525 Not Cancer Driver No 134 0.144 417 67 0.161 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0001525 Not Cancer Driver No 86 0.211 142 26 0.183 5
BSG BSG P35613 Basigin chr19 GO:0001525 Not Cancer Driver No 43 0.112 123 17 0.138 0
C1GALT1_ENST00000223122 C1GALT1 Q9NS00 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 chr7 GO:0001525 Not Cancer Driver No 43 0.118 68 5 0.074 0
CALCRL CALCRL Q16602 Calcitonin gene-related peptide type 1 receptor chr2 GO:0001525 Not Cancer Driver No 122 0.265 8 4 0.5 0
CALD1 CALD1 Q05682 Caldesmon chr7 GO:0001525 Not Cancer Driver No 133 0.168 793 133 0.168 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0001525 Census, Compendium Yes 142 0.296 106 12 0.113 1
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0001525 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCDC134 CCDC134 Q9H6E4 Coiled-coil domain-containing protein 134 chr22 GO:0001525 Not Cancer Driver No 24 0.105 43 3 0.07 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0001525 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL8 CCL8 P80075 C-C motif chemokine 8 chr17 GO:0001525 Not Cancer Driver No 17 0.172 0 0 0.0 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0001525 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0001525 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0001525 Not Cancer Driver No 66 0.185 19 1 0.053 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0001525 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0001525 Not Cancer Driver No 65 0.169 221 34 0.154 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0001525 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEMIP2 CEMIP2 Q9UHN6 Cell surface hyaluronidase chr9 GO:0001525 Not Cancer Driver No 198 0.143 229 26 0.114 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0001525 Not Cancer Driver No 24 0.126 6 1 0.167 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 GO:0001525 Not Cancer Driver No 24 0.095 49 4 0.082 0
COL15A1 COL15A1 P39059 Collagen alpha-1(XV) chain chr9 GO:0001525 Not Cancer Driver No 274 0.197 978 203 0.208 0
COL18A1 COL18A1 P39060 Collagen alpha-1(XVIII) chain chr21 GO:0001525 Not Cancer Driver No 179 0.102 1284 142 0.111 0
COL22A1 COL22A1 Q8NFW1 Collagen alpha-1(XXII) chain chr8 GO:0001525 Not Cancer Driver No 571 0.351 1215 420 0.346 0
COL4A2 COL4A2 P08572 Collagen alpha-2(IV) chain chr13 GO:0001525 Not Cancer Driver No 264 0.154 1462 234 0.16 2
COL8A1_ENST00000273342 COL8A1 P27658 Collagen alpha-1(VIII) chain chr3 GO:0001525 Not Cancer Driver No 156 0.21 586 133 0.227 0
COL8A2_ENST00000303143 COL8A2 P25067 Collagen alpha-2(VIII) chain chr1 GO:0001525 Not Cancer Driver No 75 0.107 559 58 0.104 4
CSPG4 CSPG4 Q6UVK1 Chondroitin sulfate proteoglycan 4 chr15 GO:0001525 Not Cancer Driver No 259 0.112 838 85 0.101 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0001525 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL17 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0001525 Not Cancer Driver No 8 0.067 44 6 0.136 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0001525 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCR3_ENST00000373693 CXCR3 P49682 C-X-C chemokine receptor type 3 chrX GO:0001525 Not Cancer Driver No 58 0.158 15 0 0.0 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0001525 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0001525 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0001525 Not Cancer Driver No 102 0.114 485 61 0.126 4
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0001525 Not Cancer Driver No 75 0.109 73 15 0.205 7
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 GO:0001525 Not Cancer Driver No 91 0.169 219 28 0.128 1
ECSCR ECSCR Q19T08 Endothelial cell-specific chemotaxis regulator chr5 GO:0001525 Not Cancer Driver No 5 0.024 127 3 0.024 0
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0001525 Not Cancer Driver No 21 0.118 87 13 0.149 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0001525 Not Cancer Driver No 29 0.141 46 5 0.109 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0001525 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFL7_ENST00000308874 EGFL7 Q9UHF1 Epidermal growth factor-like protein 7 chr9 GO:0001525 Not Cancer Driver No 24 0.088 36 2 0.056 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0001525 Not Cancer Driver No 149 0.134 410 51 0.124 1
ELK3 ELK3 P41970 ETS domain-containing protein Elk-3 chr12 GO:0001525 Not Cancer Driver No 58 0.143 163 16 0.098 0
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:0001525 Not Cancer Driver No 25 0.095 109 15 0.138 0
ENPEP ENPEP Q07075 Glutamyl aminopeptidase chr4 GO:0001525 Compendium Yes 235 0.246 130 44 0.338 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0001525 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPGN EPGN Q6UW88 Epigen chr4 GO:0001525 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0001525 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0001525 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0001525 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0001525 Not Cancer Driver No 155 0.155 137 16 0.117 0
EPHB4 EPHB4 P54760 Ephrin type-B receptor 4 chr7 GO:0001525 Not Cancer Driver No 125 0.127 184 19 0.103 11
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 GO:0001525 Not Cancer Driver No 78 0.083 70 2 0.029 0
EREG EREG O14944 Proepiregulin chr4 GO:0001525 Not Cancer Driver No 26 0.154 10 3 0.3 0
ESM1 ESM1 Q9NQ30 Endothelial cell-specific molecule 1 chr5 GO:0001525 Not Cancer Driver No 44 0.239 37 11 0.297 0
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0001525 Not Cancer Driver No 158 0.208 6 2 0.333 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0001525 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0001525 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0001525 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0001525 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF6 FGF6 P10767 Fibroblast growth factor 6 chr12 GO:0001525 Not Cancer Driver No 65 0.312 0 0 0.0 0
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0001525 Not Cancer Driver No 41 0.197 43 10 0.233 1
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0001525 Census, Compendium Yes 238 0.29 228 44 0.193 72
FLNA FLNA P21333 Filamin-A chrX GO:0001525 Census Yes 416 0.157 1456 214 0.147 28
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0001525 Not Cancer Driver No 299 0.223 103 20 0.194 0
FMNL3_ENST00000550488 FMNL3 Q8IVF7 Formin-like protein 3 chr12 GO:0001525 Not Cancer Driver No 140 0.136 284 37 0.13 0
FN1 FN1 P02751 Fibronectin chr2 GO:0001525 Compendium Yes 394 0.159 1243 185 0.149 8
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0001525 Not Cancer Driver No 33 0.06 411 24 0.058 32
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0001525 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0001525 Not Cancer Driver No 72 0.104 146 3 0.021 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 GO:0001525 Not Cancer Driver No 79 0.114 570 68 0.119 1
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0001525 Census, Compendium Yes 72 0.15 370 49 0.132 6
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0001525 Not Cancer Driver No 74 0.207 92 21 0.228 5
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0001525 Not Cancer Driver No 66 0.177 104 21 0.202 2
GPR4 GPR4 P46093 G-protein coupled receptor 4 chr19 GO:0001525 Not Cancer Driver No 57 0.157 44 8 0.182 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0001525 Not Cancer Driver No 38 0.187 12 1 0.083 0
HAND1 HAND1 O96004 Heart- and neural crest derivatives-expressed protein 1 chr5 GO:0001525 Not Cancer Driver No 35 0.163 166 29 0.175 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0001525 Not Cancer Driver No 47 0.217 124 29 0.234 0
HEY1_ENST00000354724 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:0001525 Census Yes 33 0.109 172 15 0.087 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0001525 Census Yes 118 0.143 435 51 0.117 0
HIF3A HIF3A Q9Y2N7 Hypoxia-inducible factor 3-alpha chr19 GO:0001525 Not Cancer Driver No 146 0.218 361 94 0.26 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0001525 Not Cancer Driver No 46 0.16 81 13 0.16 0
HOXA3_ENST00000396352 HOXA3 O43365 Homeobox protein Hox-A3 chr7 GO:0001525 Not Cancer Driver No 86 0.194 417 84 0.201 0
HOXA7 HOXA7 P31268 Homeobox protein Hox-A7 chr7 GO:0001525 Not Cancer Driver No 60 0.261 71 15 0.211 0
HOXB13 HOXB13 Q92826 Homeobox protein Hox-B13 chr17 GO:0001525 Not Cancer Driver No 61 0.215 179 37 0.207 1
HOXB3_ENST00000498678 HOXB3 P14651 Homeobox protein Hox-B3 chr17 GO:0001525 Not Cancer Driver No 74 0.172 398 66 0.166 0
HPSE HPSE Q9Y251 Heparanase chr4 GO:0001525 Not Cancer Driver No 90 0.166 16 2 0.125 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0001525 Not Cancer Driver No 121 0.23 277 75 0.271 2
HS6ST1 HS6ST1 O60243 Heparan-sulfate 6-O-sulfotransferase 1 chr2 GO:0001525 Not Cancer Driver No 60 0.146 66 14 0.212 6
HSPG2 HSPG2 P98160 Basement membrane-specific heparan sulfate proteoglycan core protein chr1 GO:0001525 Compendium Yes 506 0.115 1709 194 0.114 1
HTATIP2_ENST00000443524 HTATIP2 Q9BUP3 Oxidoreductase HTATIP2 chr11 GO:0001525 Not Cancer Driver No 22 0.091 14 0 0.0 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0001525 Not Cancer Driver No 20 0.129 17 6 0.353 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0001525 Not Cancer Driver No 19 0.098 16 3 0.188 0
ITGA2B ITGA2B P08514 Integrin alpha-IIb chr17 GO:0001525 Not Cancer Driver No 133 0.128 188 31 0.165 34
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0001525 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0001525 Census Yes 153 0.146 92 9 0.098 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0001525 Not Cancer Driver No 124 0.157 66 5 0.076 30
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0001525 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0001525 Not Cancer Driver No 50 0.161 62 11 0.177 2
JUN JUN P05412 Transcription factor Jun chr1 GO:0001525 Census Yes 35 0.106 281 25 0.089 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0001525 Census, Compendium Yes 357 0.263 275 55 0.2 2
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0001525 Compendium Yes 77 0.168 366 40 0.109 0
KRIT1_ENST00000394505 KRIT1 O00522 Krev interaction trapped protein 1 chr7 GO:0001525 Not Cancer Driver No 80 0.109 113 17 0.15 2
LEP LEP P41159 Leptin chr7 GO:0001525 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0001525 Not Cancer Driver No 243 0.209 57 11 0.193 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0001525 Not Cancer Driver No 39 0.108 25 1 0.04 0
MCAM MCAM P43121 Cell surface glycoprotein MUC18 chr11 GO:0001525 Not Cancer Driver No 91 0.141 305 46 0.151 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0001525 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 GO:0001525 Not Cancer Driver No 89 0.228 267 62 0.232 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 GO:0001525 Not Cancer Driver No 70 0.23 274 63 0.23 0
MFGE8_ENST00000566497 MFGE8 Q08431 Lactadherin chr15 GO:0001525 Not Cancer Driver No 64 0.165 14 0 0.0 0
MINAR1 MINAR1 Q9UPX6 Major intrinsically disordered Notch2-binding receptor 1 chr15 GO:0001525 Not Cancer Driver No 171 0.187 584 104 0.178 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0001525 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP19 MMP19 Q99542 Matrix metalloproteinase-19 chr12 GO:0001525 Not Cancer Driver No 94 0.185 98 20 0.204 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0001525 Not Cancer Driver No 123 0.186 29 6 0.207 2
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0001525 Not Cancer Driver No 23 0.133 26 4 0.154 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0001525 Census, Compendium Yes 310 0.158 1120 160 0.143 17
NAA15 NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit chr4 GO:0001525 Not Cancer Driver No 95 0.11 115 17 0.148 0
NCL NCL P19338 Nucleolin chr2 GO:0001525 Not Cancer Driver No 85 0.12 569 68 0.12 0
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:0001525 Not Cancer Driver No 125 0.22 129 29 0.225 1
NINJ1 NINJ1 Q92982 Ninjurin-1 chr9 GO:0001525 Not Cancer Driver No 17 0.112 29 0 0.0 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0001525 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0001525 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOTCH3 NOTCH3 Q9UM47 Neurogenic locus notch homolog protein 3 chr19 GO:0001525 Not Cancer Driver No 306 0.132 557 81 0.145 110
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0001525 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOX5 NOX5 Q96PH1 NADPH oxidase 5 chr15 GO:0001525 Not Cancer Driver No 118 0.154 95 9 0.095 0
NRCAM_ENST00000425651 NRCAM Q92823 Neuronal cell adhesion molecule chr7 GO:0001525 Not Cancer Driver No 210 0.161 471 75 0.159 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0001525 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0001525 Not Cancer Driver No 161 0.173 207 45 0.217 0
NUS1 NUS1 Q96E22 Dehydrodolichyl diphosphate synthase complex subunit NUS1 chr6 GO:0001525 Not Cancer Driver No 21 0.072 13 0 0.0 1
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0001525 Not Cancer Driver No 29 0.105 139 8 0.058 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 GO:0001525 Not Cancer Driver No 46 0.081 206 14 0.068 30
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0001525 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:0001525 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 GO:0001525 Not Cancer Driver No 48 0.201 73 13 0.178 0
PDE3B PDE3B Q13370 cGMP-inhibited 3',5'-cyclic phosphodiesterase B chr11 GO:0001525 Not Cancer Driver No 135 0.121 393 37 0.094 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0001525 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0001525 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0001525 Census, Compendium Yes 164 0.148 231 44 0.19 7
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0001525 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0001525 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0001525 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 GO:0001525 Not Cancer Driver No 100 0.133 156 26 0.167 0
PKNOX1 PKNOX1 P55347 Homeobox protein PKNOX1 chr21 GO:0001525 Not Cancer Driver No 60 0.138 279 36 0.129 0
PLCD3 PLCD3 Q8N3E9 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 chr17 GO:0001525 Not Cancer Driver No 61 0.077 229 22 0.096 0
PLXDC1 PLXDC1 Q8IUK5 Plexin domain-containing protein 1 chr17 GO:0001525 Not Cancer Driver No 66 0.132 170 18 0.106 0
PLXND1 PLXND1 Q9Y4D7 Plexin-D1 chr3 GO:0001525 Not Cancer Driver No 246 0.128 321 35 0.109 0
POFUT1 POFUT1 Q9H488 GDP-fucose protein O-fucosyltransferase 1 chr20 GO:0001525 Not Cancer Driver No 56 0.144 17 2 0.118 0
PRCP_ENST00000313010 PRCP P42785 Lysosomal Pro-X carboxypeptidase chr11 GO:0001525 Not Cancer Driver No 58 0.117 0 0 0.0 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0001525 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0001525 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0001525 Compendium Yes 118 0.134 246 34 0.138 0
PRKX PRKX P51817 cAMP-dependent protein kinase catalytic subunit PRKX chrX GO:0001525 Not Cancer Driver No 54 0.151 69 3 0.043 0
PROK1 PROK1 P58294 Prokineticin-1 chr1 GO:0001525 Not Cancer Driver No 21 0.2 0 0 0.0 0
PROK2 PROK2 Q9HC23 Prokineticin-2 chr3 GO:0001525 Not Cancer Driver No 18 0.14 23 1 0.043 6
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0001525 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0001525 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0001525 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPRB_ENST00000261266 PTPRB P23467 Receptor-type tyrosine-protein phosphatase beta chr12 GO:0001525 Census, Compendium Yes 425 0.213 302 65 0.215 0
RAMP1 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 GO:0001525 Not Cancer Driver No 16 0.108 0 0 0.0 0
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0001525 Not Cancer Driver No 18 0.103 34 6 0.176 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0001525 Not Cancer Driver No 97 0.105 197 19 0.096 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0001525 Not Cancer Driver No 73 0.076 505 48 0.095 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0001525 Not Cancer Driver No 49 0.098 151 19 0.126 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0001525 Not Cancer Driver No 52 0.265 19 2 0.105 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 GO:0001525 Not Cancer Driver No 39 0.182 0 0 0.0 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 GO:0001525 Census, Compendium Yes 560 0.108 623 75 0.12 3
ROBO4 ROBO4 Q8WZ75 Roundabout homolog 4 chr11 GO:0001525 Not Cancer Driver No 194 0.193 697 133 0.191 1
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0001525 Not Cancer Driver No 57 0.109 182 17 0.093 4
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0001525 Census Yes 39 0.386 28 14 0.5 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0001525 Not Cancer Driver No 86 0.225 29 6 0.207 0
SAT1 SAT1 P21673 Diamine acetyltransferase 1 chrX GO:0001525 Not Cancer Driver No 29 0.17 0 0 0.0 0
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0001525 Not Cancer Driver No 116 0.188 531 103 0.194 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0001525 Not Cancer Driver No 123 0.162 122 26 0.213 4
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0001525 Not Cancer Driver No 78 0.194 7 2 0.286 0
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0001525 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SH2D2A_ENST00000368199 SH2D2A Q9NP31 SH2 domain-containing protein 2A chr1 GO:0001525 Not Cancer Driver No 51 0.131 272 42 0.154 0
SHB SHB Q15464 SH2 domain-containing adapter protein B chr9 GO:0001525 Not Cancer Driver No 56 0.11 334 36 0.108 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0001525 Not Cancer Driver No 84 0.144 397 58 0.146 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0001525 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLC12A6_ENST00000558667 SLC12A6 Q9UHW9 Solute carrier family 12 member 6 chr15 GO:0001525 Not Cancer Driver No 168 0.146 280 46 0.164 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0001525 Compendium Yes 81 0.196 378 59 0.156 2
SOX18 SOX18 P35713 Transcription factor SOX-18 chr20 GO:0001525 Not Cancer Driver No 10 0.026 321 10 0.031 2
SRF SRF P11831 Serum response factor chr6 GO:0001525 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 GO:0001525 Not Cancer Driver No 78 0.113 343 46 0.134 0
SRPX2 SRPX2 O60687 Sushi repeat-containing protein SRPX2 chrX GO:0001525 Not Cancer Driver No 86 0.185 64 13 0.203 0
STAB2 STAB2 Q8WWQ8 Stabilin-2 chr12 GO:0001525 Not Cancer Driver No 482 0.189 101 16 0.158 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0001525 Census Yes 96 0.151 131 27 0.206 5
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0001525 Census Yes 54 0.163 305 53 0.174 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0001525 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX4_ENST00000240335 TBX4 P57082 T-box transcription factor TBX4 chr17 GO:0001525 Not Cancer Driver No 99 0.182 318 69 0.217 2
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0001525 Not Cancer Driver No 55 0.307 120 40 0.333 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0001525 Not Cancer Driver No 219 0.195 126 22 0.175 10
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0001525 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFBI TGFBI Q15582 Transforming growth factor-beta-induced protein ig-h3 chr5 GO:0001525 Not Cancer Driver No 108 0.158 58 19 0.328 23
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0001525 Not Cancer Driver No 86 0.171 23 3 0.13 15
THSD7A THSD7A Q9UPZ6 Thrombospondin type-1 domain-containing protein 7A chr7 GO:0001525 Not Cancer Driver No 408 0.246 224 74 0.33 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0001525 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIE1 TIE1 P35590 Tyrosine-protein kinase receptor Tie-1 chr1 GO:0001525 Not Cancer Driver No 200 0.176 223 46 0.206 0
TMEM100 TMEM100 Q9NV29 Transmembrane protein 100 chr17 GO:0001525 Not Cancer Driver No 29 0.216 0 0 0.0 0
TNFAIP2_ENST00000333007 TNFAIP2 Q03169 Tumor necrosis factor alpha-induced protein 2 chr14 GO:0001525 Not Cancer Driver No 58 0.089 152 4 0.026 0
TNFRSF12A TNFRSF12A Q9NP84 Tumor necrosis factor receptor superfamily member 12A chr16 GO:0001525 Not Cancer Driver No 8 0.062 0 0 0.0 0
TNFSF12 TNFSF12 O43508 Tumor necrosis factor ligand superfamily member 12 chr17 GO:0001525 Not Cancer Driver No 28 0.112 109 8 0.073 0
TSPAN12_ENST00000415871 TSPAN12 O95859 Tetraspanin-12 chr7 GO:0001525 Not Cancer Driver No 51 0.167 9 3 0.333 7
TYMP_ENST00000395680 TYMP P19971 Thymidine phosphorylase chr22 GO:0001525 Not Cancer Driver No 28 0.058 143 7 0.049 5
UBP1 UBP1 Q9NZI7 Upstream-binding protein 1 chr3 GO:0001525 Not Cancer Driver No 58 0.107 233 29 0.124 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:0001525 Not Cancer Driver No 155 0.164 117 20 0.171 0
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 GO:0001525 Not Cancer Driver No 39 0.107 215 18 0.084 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0001525 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0001525 Not Cancer Driver No 153 0.181 102 18 0.176 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0001525 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEZF1 VEZF1 Q14119 Vascular endothelial zinc finger 1 chr17 GO:0001525 Not Cancer Driver No 56 0.107 332 32 0.096 0
WARS WARS1 P23381 Tryptophan--tRNA ligase, cytoplasmic chr14 GO:0001525 Not Cancer Driver No 62 0.132 90 13 0.144 1
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 GO:0001525 Not Cancer Driver No 61 0.122 400 43 0.107 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0001525 Not Cancer Driver No 93 0.266 18 9 0.5 4
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0001525 Not Cancer Driver No 19 0.073 169 9 0.053 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 GO:0001525 Not Cancer Driver No 30 0.122 81 10 0.123 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0001525 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZNF304_ENST00000391705 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0001525 Not Cancer Driver No 126 0.191 54 12 0.222 0