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Total number of protein in "GO:0000987" GO term:  132

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0000987 Not Cancer Driver No 129 0.152 351 75 0.214 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0000987 Census Yes 77 0.098 511 56 0.11 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0000987 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARNTL2 ARNTL2 Q8WYA1 Aryl hydrocarbon receptor nuclear translocator-like protein 2 chr12 GO:0000987 Not Cancer Driver No 79 0.124 264 38 0.144 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0000987 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASCL2 ASCL2 Q99929 Achaete-scute homolog 2 chr11 GO:0000987 Not Cancer Driver No 2 0.01 166 1 0.006 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0000987 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0000987 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0000987 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATF7_ENST00000456903 ATF7 P17544 Cyclic AMP-dependent transcription factor ATF-7 chr12 GO:0000987 Not Cancer Driver No 45 0.093 468 45 0.096 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0000987 Not Cancer Driver No 31 0.097 254 23 0.091 0
BHLHE40 BHLHE40 O14503 Class E basic helix-loop-helix protein 40 chr3 GO:0000987 Not Cancer Driver No 52 0.126 242 31 0.128 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 GO:0000987 Not Cancer Driver No 21 0.044 213 10 0.047 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0000987 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRF2 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 GO:0000987 Not Cancer Driver No 40 0.095 138 13 0.094 0
CIART CIART Q8N365 Circadian-associated transcriptional repressor chr1 GO:0000987 Not Cancer Driver No 59 0.153 272 40 0.147 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0000987 Not Cancer Driver No 83 0.098 458 38 0.083 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0000987 Census Yes 25 0.076 277 23 0.083 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0000987 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0000987 Census Yes 68 0.131 372 50 0.134 0
CREB3L2 CREB3L2 Q70SY1 Cyclic AMP-responsive element-binding protein 3-like protein 2 chr7 GO:0000987 Census Yes 61 0.117 364 46 0.126 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0000987 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREB3L4_ENST00000271889 CREB3L4 Q8TEY5 Cyclic AMP-responsive element-binding protein 3-like protein 4 chr1 GO:0000987 Not Cancer Driver No 55 0.139 241 27 0.112 0
CREB5 CREB5 Q02930 Cyclic AMP-responsive element-binding protein 5 chr7 GO:0000987 Not Cancer Driver No 92 0.181 494 89 0.18 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0000987 Not Cancer Driver No 76 0.13 91 5 0.055 0
CXXC1_ENST00000285106 CXXC1 Q9P0U4 CXXC-type zinc finger protein 1 chr18 GO:0000987 Not Cancer Driver No 115 0.175 366 65 0.178 0
DMRT1 DMRT1 Q9Y5R6 Doublesex- and mab-3-related transcription factor 1 chr9 GO:0000987 Not Cancer Driver No 60 0.161 282 47 0.167 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0000987 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F2 E2F2 Q14209 Transcription factor E2F2 chr1 GO:0000987 Not Cancer Driver No 42 0.096 282 28 0.099 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 GO:0000987 Not Cancer Driver No 46 0.099 253 20 0.079 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0000987 Not Cancer Driver No 122 0.134 554 70 0.126 0
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 GO:0000987 Not Cancer Driver No 132 0.152 582 85 0.146 0
E4F1 E4F1 Q66K89 Transcription factor E4F1 chr16 GO:0000987 Not Cancer Driver No 84 0.107 462 46 0.1 0
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0000987 Census, Compendium Yes 67 0.108 446 53 0.119 0
ELL2 ELL2 O00472 RNA polymerase II elongation factor ELL2 chr5 GO:0000987 Not Cancer Driver No 90 0.141 421 63 0.15 0
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0000987 Not Cancer Driver No 50 0.126 186 13 0.07 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0000987 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0000987 Not Cancer Driver No 90 0.17 92 11 0.12 1
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0000987 Not Cancer Driver No 90 0.208 35 7 0.2 4
ESRRG_ENST00000408911 ESRRG P62508 Estrogen-related receptor gamma chr1 GO:0000987 Not Cancer Driver No 135 0.295 76 29 0.382 0
FIGLA FIGLA Q6QHK4 Factor in the germline alpha chr2 GO:0000987 Not Cancer Driver No 22 0.1 154 17 0.11 0
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:0000987 Not Cancer Driver No 47 0.129 215 25 0.116 0
FOXN2 FOXN2 P32314 Forkhead box protein N2 chr2 GO:0000987 Not Cancer Driver No 52 0.121 215 18 0.084 0
FOXN3 FOXN3 O00409 Forkhead box protein N3 chr14 GO:0000987 Not Cancer Driver No 76 0.155 365 61 0.167 0
FOXN4 FOXN4 Q96NZ1 Forkhead box protein N4 chr12 GO:0000987 Not Cancer Driver No 60 0.116 377 34 0.09 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0000987 Census, Compendium Yes 111 0.251 364 87 0.239 2
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0000987 Not Cancer Driver No 47 0.217 124 29 0.234 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0000987 Not Cancer Driver No 47 0.098 135 10 0.074 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0000987 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES3 HES3 Q5TGS1 Transcription factor HES-3 chr1 GO:0000987 Not Cancer Driver No 13 0.07 129 10 0.078 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0000987 Census Yes 118 0.143 435 51 0.117 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 GO:0000987 Census Yes 6 0.056 107 6 0.056 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0000987 Census Yes 12 0.11 109 12 0.11 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0000987 Not Cancer Driver No 38 0.182 207 38 0.184 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0000987 Not Cancer Driver No 85 0.244 180 41 0.228 0
ISL2 ISL2 Q96A47 Insulin gene enhancer protein ISL-2 chr15 GO:0000987 Not Cancer Driver No 42 0.117 167 16 0.096 0
JDP2_ENST00000435893 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 GO:0000987 Not Cancer Driver No 16 0.098 142 13 0.092 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0000987 Census Yes 35 0.106 281 25 0.089 0
KLF1 KLF1 Q13351 Krueppel-like factor 1 chr19 GO:0000987 Not Cancer Driver No 33 0.091 279 23 0.082 1
MAF1_ENST00000532522 MAF1 Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog chr8 GO:0000987 Not Cancer Driver No 22 0.086 74 4 0.054 0
MAX MAX P61244 Protein max chr14 GO:0000987 Census, Compendium Yes 45 0.281 160 45 0.281 9
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 GO:0000987 Census Yes 80 0.152 408 69 0.169 7
MIXL1_ENST00000366810 MIXL1 Q9H2W2 Homeobox protein MIXL1 chr1 GO:0000987 Not Cancer Driver No 18 0.078 157 10 0.064 0
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0000987 Not Cancer Driver No 106 0.124 554 66 0.119 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0000987 Not Cancer Driver No 39 0.129 197 16 0.081 7
MTF1 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 GO:0000987 Not Cancer Driver No 115 0.153 553 76 0.137 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0000987 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0000987 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0000987 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0000987 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0000987 Not Cancer Driver No 89 0.368 118 44 0.373 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0000987 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0000987 Not Cancer Driver No 36 0.161 132 20 0.152 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0000987 Not Cancer Driver No 84 0.236 202 52 0.257 2
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0000987 Not Cancer Driver No 26 0.068 210 14 0.067 2
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0000987 Not Cancer Driver No 27 0.114 178 18 0.101 0
NEUROG2 NEUROG2 Q9H2A3 Neurogenin-2 chr4 GO:0000987 Not Cancer Driver No 32 0.118 209 29 0.139 0
NFE2_ENST00000312156 NFE2 Q16621 Transcription factor NF-E2 45 kDa subunit chr12 GO:0000987 Not Cancer Driver No 64 0.172 295 51 0.173 0
NFE4 NFE4 Q86UQ8 Transcription factor NF-E4 chr7 GO:0000987 Not Cancer Driver No 15 0.084 136 11 0.081 0
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0000987 Not Cancer Driver No 84 0.308 206 65 0.316 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0000987 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0000987 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR2F1_ENST00000327111 NR2F1 P10589 COUP transcription factor 1 chr5 GO:0000987 Not Cancer Driver No 67 0.158 110 6 0.055 4
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0000987 Census Yes 83 0.133 298 37 0.124 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0000987 Not Cancer Driver No 62 0.149 296 48 0.162 23
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0000987 Census Yes 160 0.124 948 116 0.122 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0000987 Census Yes 72 0.143 44 4 0.091 3
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0000987 Not Cancer Driver No 83 0.13 72 6 0.083 0
PTF1A PTF1A Q7RTS3 Pancreas transcription factor 1 subunit alpha chr10 GO:0000987 Not Cancer Driver No 35 0.107 231 31 0.134 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0000987 Census, Compendium Yes 70 0.152 167 14 0.084 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0000987 Not Cancer Driver No 176 0.132 241 21 0.087 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0000987 Compendium Yes 90 0.195 184 26 0.141 0
RXRB_ENST00000374680 RXRB P28702 Retinoic acid receptor RXR-beta chr6 GO:0000987 Not Cancer Driver No 61 0.114 279 25 0.09 0
RXRG RXRG P48443 Retinoic acid receptor RXR-gamma chr1 GO:0000987 Not Cancer Driver No 103 0.222 161 41 0.255 0
SCRT2 SCRT2 Q9NQ03 Transcriptional repressor scratch 2 chr20 GO:0000987 Not Cancer Driver No 19 0.062 168 4 0.024 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0000987 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0000987 Census, Compendium Yes 97 0.228 111 19 0.171 5
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0000987 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0000987 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNAPC3_ENST00000610884 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 GO:0000987 Not Cancer Driver No 30 0.073 99 2 0.02 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0000987 Compendium Yes 86 0.169 495 82 0.166 18
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0000987 Not Cancer Driver No 96 0.122 599 71 0.119 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0000987 Not Cancer Driver No 66 0.085 587 37 0.063 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0000987 Not Cancer Driver No 46 0.17 187 34 0.182 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0000987 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0000987 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0000987 Not Cancer Driver No 44 0.087 443 42 0.095 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0000987 Census Yes 54 0.163 305 53 0.174 0
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 GO:0000987 Census Yes 105 0.154 680 105 0.154 3
TCF15 TCF15 Q12870 Transcription factor 15 chr20 GO:0000987 Not Cancer Driver No 19 0.095 134 4 0.03 0
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0000987 Not Cancer Driver No 55 0.307 120 40 0.333 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0000987 Census Yes 52 0.08 649 52 0.08 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 GO:0000987 Compendium Yes 141 0.211 662 136 0.205 13
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 GO:0000987 Not Cancer Driver No 52 0.122 157 24 0.153 1
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0000987 Not Cancer Driver No 114 0.248 306 75 0.245 6
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0000987 Compendium Yes 61 0.18 285 52 0.182 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 GO:0000987 Not Cancer Driver No 68 0.135 169 23 0.136 0
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 GO:0000987 Not Cancer Driver No 82 0.2 245 47 0.192 0
TIPARP TIPARP Q7Z3E1 Protein mono-ADP-ribosyltransferase TIPARP chr3 GO:0000987 Not Cancer Driver No 65 0.099 200 20 0.1 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0000987 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0000987 Census, Compendium Yes 120 0.114 537 61 0.114 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0000987 Not Cancer Driver No 23 0.114 132 11 0.083 7
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0000987 Not Cancer Driver No 97 0.122 353 49 0.139 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0000987 Not Cancer Driver No 64 0.15 102 16 0.157 14
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0000987 Not Cancer Driver No 19 0.073 169 9 0.053 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0000987 Not Cancer Driver No 37 0.089 336 26 0.077 2
YY2 YY2 O15391 Transcription factor YY2 chrX GO:0000987 Not Cancer Driver No 61 0.164 268 36 0.134 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0000987 Compendium Yes 103 0.191 353 70 0.198 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0000987 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZNF395 ZNF395 Q9H8N7 Zinc finger protein 395 chr8 GO:0000987 Not Cancer Driver No 70 0.136 342 46 0.135 0
ZNF516 ZNF516 Q92618 Zinc finger protein 516 chr18 GO:0000987 Not Cancer Driver No 177 0.152 861 131 0.152 0
ZNF536 ZNF536 O15090 Zinc finger protein 536 chr19 GO:0000987 Not Cancer Driver No 596 0.458 991 445 0.449 0