Total number of protein in "GO:0000781" GO term: 163
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACD_ENST00000620761 | ACD | Q96AP0 | Adrenocortical dysplasia protein homolog | chr16 | GO:0000781 | Not Cancer Driver | No | 49 | 0.107 | 256 | 34 | 0.133 | 1 |
ALYREF | ALYREF | Q86V81 | THO complex subunit 4 | chr17 | GO:0000781 | Not Cancer Driver | No | 32 | 0.125 | 223 | 26 | 0.117 | 0 |
APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0000781 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
ATF7_ENST00000456903 | ATF7 | P17544 | Cyclic AMP-dependent transcription factor ATF-7 | chr12 | GO:0000781 | Not Cancer Driver | No | 45 | 0.093 | 468 | 45 | 0.096 | 0 |
ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0000781 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:0000781 | Census, Compendium | Yes | 338 | 0.128 | 106 | 14 | 0.132 | 1 |
ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0000781 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
BLM | BLM | P54132 | Bloom syndrome protein | chr15 | GO:0000781 | Census | Yes | 153 | 0.108 | 667 | 70 | 0.105 | 8 |
BRCA2_ENST00000544455 | BRCA2 | P51587 | Breast cancer type 2 susceptibility protein | chr13 | GO:0000781 | Census, Compendium | Yes | 457 | 0.134 | 1542 | 225 | 0.146 | 46 |
CBX1_ENST00000225603 | CBX1 | P83916 | Chromobox protein homolog 1 | chr17 | GO:0000781 | Not Cancer Driver | No | 31 | 0.168 | 154 | 25 | 0.162 | 0 |
CBX3_ENST00000396386 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | GO:0000781 | Not Cancer Driver | No | 23 | 0.126 | 119 | 18 | 0.151 | 0 |
CBX5 | CBX5 | P45973 | Chromobox protein homolog 5 | chr12 | GO:0000781 | Not Cancer Driver | No | 21 | 0.11 | 116 | 12 | 0.103 | 0 |
CCDC155 | KASH5 | Q8N6L0 | Protein KASH5 | chr19 | GO:0000781 | Not Cancer Driver | No | 88 | 0.157 | 401 | 70 | 0.175 | 0 |
CDC73 | CDC73 | Q6P1J9 | Parafibromin | chr1 | GO:0000781 | Census, Compendium | Yes | 110 | 0.207 | 210 | 39 | 0.186 | 2 |
CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0000781 | Not Cancer Driver | No | 40 | 0.135 | 1 | 0 | 0.0 | 0 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0000781 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
CHD4 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | GO:0000781 | Census, Compendium | Yes | 419 | 0.219 | 974 | 177 | 0.182 | 6 |
CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0000781 | Not Cancer Driver | No | 58 | 0.122 | 86 | 16 | 0.186 | 0 |
CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:0000781 | Census, Compendium | Yes | 335 | 0.617 | 157 | 130 | 0.828 | 13 |
CTC1 | CTC1 | Q2NKJ3 | CST complex subunit CTC1 | chr17 | GO:0000781 | Not Cancer Driver | No | 142 | 0.117 | 103 | 8 | 0.078 | 9 |
DCLRE1B | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0000781 | Not Cancer Driver | No | 65 | 0.122 | 127 | 17 | 0.134 | 0 |
DDB1 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0000781 | Not Cancer Driver | No | 126 | 0.111 | 50 | 8 | 0.16 | 4 |
DHX36 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:0000781 | Not Cancer Driver | No | 159 | 0.158 | 222 | 39 | 0.176 | 0 |
DMC1 | DMC1 | Q14565 | Meiotic recombination protein DMC1/LIM15 homolog | chr22 | GO:0000781 | Not Cancer Driver | No | 39 | 0.115 | 49 | 5 | 0.102 | 0 |
DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0000781 | Not Cancer Driver | No | 120 | 0.113 | 52 | 8 | 0.154 | 3 |
DOT1L | DOT1L | Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | chr19 | GO:0000781 | Compendium | Yes | 178 | 0.116 | 988 | 118 | 0.119 | 0 |
DPY30 | DPY30 | Q9C005 | Protein dpy-30 homolog | chr2 | GO:0000781 | Not Cancer Driver | No | 10 | 0.101 | 57 | 6 | 0.105 | 0 |
DYDC1_ENST00000421924 | DYDC1 | Q8WWB3 | DPY30 domain-containing protein 1 | chr10 | GO:0000781 | Not Cancer Driver | No | 29 | 0.164 | 94 | 17 | 0.181 | 0 |
DYDC2_ENST00000616870 | DYDC2 | Q96IM9 | DPY30 domain-containing protein 2 | chr10 | GO:0000781 | Not Cancer Driver | No | 33 | 0.186 | 133 | 27 | 0.203 | 0 |
ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0000781 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0000781 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
EZH1 | EZH1 | Q92800 | Histone-lysine N-methyltransferase EZH1 | chr17 | GO:0000781 | Not Cancer Driver | No | 82 | 0.11 | 213 | 21 | 0.099 | 0 |
EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0000781 | Census, Compendium | Yes | 120 | 0.161 | 284 | 44 | 0.155 | 11 |
FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0000781 | Census | Yes | 35 | 0.092 | 111 | 11 | 0.099 | 0 |
GAR1 | GAR1 | Q9NY12 | H/ACA ribonucleoprotein complex subunit 1 | chr4 | GO:0000781 | Not Cancer Driver | No | 23 | 0.106 | 141 | 14 | 0.099 | 0 |
GATAD2B_ENST00000634544 | GATAD2B | Q8WXI9 | Transcriptional repressor p66-beta | chr1 | GO:0000781 | Not Cancer Driver | No | 76 | 0.128 | 510 | 67 | 0.131 | 0 |
H2AFX | H2AX | P16104 | Histone H2AX | chr11 | GO:0000781 | Not Cancer Driver | No | 20 | 0.14 | 68 | 10 | 0.147 | 0 |
H2AFY | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:0000781 | Not Cancer Driver | No | 46 | 0.124 | 125 | 19 | 0.152 | 0 |
H2AFY2 | MACROH2A2 | Q9P0M6 | Core histone macro-H2A.2 | chr10 | GO:0000781 | Not Cancer Driver | No | 59 | 0.159 | 171 | 32 | 0.187 | 0 |
H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0000781 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0000781 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
HAT1 | HAT1 | O14929 | Histone acetyltransferase type B catalytic subunit | chr2 | GO:0000781 | Not Cancer Driver | No | 51 | 0.122 | 14 | 2 | 0.143 | 0 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | GO:0000781 | Not Cancer Driver | No | 46 | 0.094 | 145 | 14 | 0.097 | 0 |
HIST1H2AA | H2AC1 | Q96QV6 | Histone H2A type 1-A | chr6 | GO:0000781 | Not Cancer Driver | No | 48 | 0.366 | 60 | 23 | 0.383 | 0 |
HIST1H2BA | H2BC1 | Q96A08 | Histone H2B type 1-A | chr6 | GO:0000781 | Not Cancer Driver | No | 30 | 0.236 | 56 | 16 | 0.286 | 0 |
HIST1H2BB | H2BC3 | P33778 | Histone H2B type 1-B | chr6 | GO:0000781 | Not Cancer Driver | No | 33 | 0.262 | 76 | 19 | 0.25 | 0 |
HIST1H4A | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 15 | 0.146 | 31 | 5 | 0.161 | 0 |
HIST1H4B | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 29 | 0.282 | 31 | 6 | 0.194 | 0 |
HIST1H4C | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 29 | 0.282 | 31 | 7 | 0.226 | 0 |
HIST1H4D | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 32 | 0.311 | 31 | 8 | 0.258 | 0 |
HIST1H4E | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 45 | 0.437 | 31 | 14 | 0.452 | 0 |
HIST1H4F | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 30 | 0.291 | 31 | 7 | 0.226 | 0 |
HIST1H4H | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 22 | 0.214 | 31 | 9 | 0.29 | 0 |
HIST1H4I | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 33 | 0.32 | 31 | 10 | 0.323 | 0 |
HIST1H4J | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 26 | 0.252 | 31 | 9 | 0.29 | 0 |
HIST1H4K | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 44 | 0.427 | 31 | 13 | 0.419 | 0 |
HIST1H4L | H4-16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 25 | 0.243 | 31 | 14 | 0.452 | 0 |
HIST3H3 | H3-4 | Q16695 | Histone H3.1t | chr1 | GO:0000781 | Not Cancer Driver | No | 37 | 0.272 | 51 | 10 | 0.196 | 0 |
HIST4H4 | H4-16 | P62805 | Histone H4 | chr12 | GO:0000781 | Not Cancer Driver | No | 21 | 0.204 | 31 | 7 | 0.226 | 0 |
HMBOX1_ENST00000397358 | HMBOX1 | Q6NT76 | Homeobox-containing protein 1 | chr8 | GO:0000781 | Not Cancer Driver | No | 55 | 0.131 | 319 | 41 | 0.129 | 0 |
HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | GO:0000781 | Census, Compendium | Yes | 68 | 0.193 | 255 | 41 | 0.161 | 0 |
KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0000781 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
LIG4 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0000781 | Not Cancer Driver | No | 134 | 0.147 | 63 | 10 | 0.159 | 2 |
LRIF1 | LRIF1 | Q5T3J3 | Ligand-dependent nuclear receptor-interacting factor 1 | chr1 | GO:0000781 | Not Cancer Driver | No | 116 | 0.151 | 520 | 74 | 0.142 | 0 |
LRWD1 | LRWD1 | Q9UFC0 | Leucine-rich repeat and WD repeat-containing protein 1 | chr7 | GO:0000781 | Not Cancer Driver | No | 75 | 0.116 | 133 | 17 | 0.128 | 0 |
MAJIN_ENST00000530444 | MAJIN | Q3KP22 | Membrane-anchored junction protein | chr11 | GO:0000781 | Not Cancer Driver | No | 17 | 0.097 | 143 | 15 | 0.105 | 0 |
MCM2 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | GO:0000781 | Not Cancer Driver | No | 104 | 0.115 | 275 | 38 | 0.138 | 1 |
MCM3_ENST00000229854 | MCM3 | P25205 | DNA replication licensing factor MCM3 | chr6 | GO:0000781 | Not Cancer Driver | No | 92 | 0.114 | 310 | 47 | 0.152 | 0 |
MCM4 | MCM4 | P33991 | DNA replication licensing factor MCM4 | chr8 | GO:0000781 | Not Cancer Driver | No | 121 | 0.14 | 215 | 35 | 0.163 | 0 |
MCM5 | MCM5 | P33992 | DNA replication licensing factor MCM5 | chr22 | GO:0000781 | Not Cancer Driver | No | 88 | 0.12 | 109 | 20 | 0.183 | 1 |
MCM6 | MCM6 | Q14566 | DNA replication licensing factor MCM6 | chr2 | GO:0000781 | Not Cancer Driver | No | 101 | 0.123 | 122 | 13 | 0.107 | 0 |
MCM7 | MCM7 | P33993 | DNA replication licensing factor MCM7 | chr7 | GO:0000781 | Not Cancer Driver | No | 101 | 0.14 | 128 | 22 | 0.172 | 0 |
MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0000781 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
MRE11 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0000781 | Not Cancer Driver | No | 84 | 0.119 | 292 | 35 | 0.12 | 1 |
MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0000781 | Census | Yes | 92 | 0.099 | 37 | 4 | 0.108 | 70 |
MTA2 | MTA2 | O94776 | Metastasis-associated protein MTA2 | chr11 | GO:0000781 | Not Cancer Driver | No | 78 | 0.117 | 283 | 32 | 0.113 | 0 |
NABP1 | NABP1 | Q96AH0 | SOSS complex subunit B2 | chr2 | GO:0000781 | Not Cancer Driver | No | 25 | 0.123 | 102 | 11 | 0.108 | 0 |
NABP2_ENST00000341463 | NABP2 | Q9BQ15 | SOSS complex subunit B1 | chr12 | GO:0000781 | Not Cancer Driver | No | 25 | 0.118 | 125 | 17 | 0.136 | 0 |
NAT10 | NAT10 | Q9H0A0 | RNA cytidine acetyltransferase | chr11 | GO:0000781 | Not Cancer Driver | No | 109 | 0.106 | 142 | 18 | 0.127 | 0 |
NBN | NBN | O60934 | Nibrin | chr8 | GO:0000781 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
NHP2 | NHP2 | Q9NX24 | H/ACA ribonucleoprotein complex subunit 2 | chr5 | GO:0000781 | Not Cancer Driver | No | 26 | 0.17 | 20 | 4 | 0.2 | 2 |
NLRP2 | NLRP2 | Q9NX02 | NACHT, LRR and PYD domains-containing protein 2 | chr19 | GO:0000781 | Not Cancer Driver | No | 257 | 0.242 | 60 | 15 | 0.25 | 0 |
NSMCE2_ENST00000522563 | NSMCE2 | Q96MF7 | E3 SUMO-protein ligase NSE2 | chr8 | GO:0000781 | Not Cancer Driver | No | 30 | 0.121 | 119 | 12 | 0.101 | 0 |
ORC1_ENST00000371566 | ORC1 | Q13415 | Origin recognition complex subunit 1 | chr1 | GO:0000781 | Not Cancer Driver | No | 100 | 0.116 | 338 | 46 | 0.136 | 5 |
ORC2 | ORC2 | Q13416 | Origin recognition complex subunit 2 | chr2 | GO:0000781 | Not Cancer Driver | No | 67 | 0.116 | 248 | 22 | 0.089 | 0 |
ORC3_ENST00000392844 | ORC3 | Q9UBD5 | Origin recognition complex subunit 3 | chr6 | GO:0000781 | Not Cancer Driver | No | 70 | 0.098 | 63 | 5 | 0.079 | 0 |
ORC4_ENST00000392857 | ORC4 | O43929 | Origin recognition complex subunit 4 | chr2 | GO:0000781 | Not Cancer Driver | No | 52 | 0.119 | 14 | 2 | 0.143 | 1 |
ORC5 | ORC5 | O43913 | Origin recognition complex subunit 5 | chr7 | GO:0000781 | Not Cancer Driver | No | 43 | 0.099 | 16 | 2 | 0.125 | 0 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0000781 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0000781 | Not Cancer Driver | No | 30 | 0.115 | 22 | 3 | 0.136 | 1 |
PIF1_ENST00000559239 | PIF1 | Q9H611 | ATP-dependent DNA helicase PIF1 | chr15 | GO:0000781 | Not Cancer Driver | No | 54 | 0.084 | 209 | 11 | 0.053 | 0 |
PINX1 | PINX1 | Q96BK5 | PIN2/TERF1-interacting telomerase inhibitor 1 | chr8 | GO:0000781 | Not Cancer Driver | No | 66 | 0.201 | 328 | 66 | 0.201 | 0 |
PML | PML | P29590 | Protein PML | chr15 | GO:0000781 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
POLD1_ENST00000440232 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | GO:0000781 | Census, Compendium | Yes | 179 | 0.162 | 214 | 31 | 0.145 | 2 |
POLR2B_ENST00000314595 | POLR2B | P30876 | DNA-directed RNA polymerase II subunit RPB2 | chr4 | GO:0000781 | Not Cancer Driver | No | 166 | 0.141 | 173 | 25 | 0.145 | 0 |
POT1 | POT1 | Q9NUX5 | Protection of telomeres protein 1 | chr7 | GO:0000781 | Census, Compendium | Yes | 113 | 0.178 | 31 | 6 | 0.194 | 9 |
PPP1CA_ENST00000376745 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | GO:0000781 | Not Cancer Driver | No | 38 | 0.115 | 27 | 6 | 0.222 | 0 |
PPP1CB_ENST00000358506 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | GO:0000781 | Not Cancer Driver | No | 47 | 0.144 | 25 | 5 | 0.2 | 5 |
PPP1CC_ENST00000335007 | PPP1CC | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | chr12 | GO:0000781 | Not Cancer Driver | No | 26 | 0.08 | 23 | 4 | 0.174 | 0 |
PPP1R10 | PPP1R10 | Q96QC0 | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | chr6 | GO:0000781 | Not Cancer Driver | No | 114 | 0.121 | 798 | 100 | 0.125 | 0 |
PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0000781 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | GO:0000781 | Not Cancer Driver | No | 11 | 0.069 | 52 | 3 | 0.058 | 0 |
PURA | PURA | Q00577 | Transcriptional activator protein Pur-alpha | chr5 | GO:0000781 | Not Cancer Driver | No | 22 | 0.068 | 188 | 10 | 0.053 | 6 |
RAD17 | RAD17 | O75943 | Cell cycle checkpoint protein RAD17 | chr5 | GO:0000781 | Census | Yes | 78 | 0.115 | 207 | 19 | 0.092 | 0 |
RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0000781 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
RAD51AP1 | RAD51AP1 | Q96B01 | RAD51-associated protein 1 | chr12 | GO:0000781 | Not Cancer Driver | No | 46 | 0.131 | 335 | 43 | 0.128 | 0 |
RAD51D_ENST00000394589 | RAD51D | O75771 | DNA repair protein RAD51 homolog 4 | chr17 | GO:0000781 | Not Cancer Driver | No | 34 | 0.104 | 49 | 10 | 0.204 | 0 |
RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0000781 | Not Cancer Driver | No | 42 | 0.124 | 47 | 5 | 0.106 | 3 |
RBBP4 | RBBP4 | Q09028 | Histone-binding protein RBBP4 | chr1 | GO:0000781 | Not Cancer Driver | No | 53 | 0.125 | 169 | 23 | 0.136 | 0 |
RBBP7_ENST00000380087 | RBBP7 | Q16576 | Histone-binding protein RBBP7 | chrX | GO:0000781 | Not Cancer Driver | No | 67 | 0.158 | 138 | 19 | 0.138 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | GO:0000781 | Census, Compendium | Yes | 138 | 0.114 | 608 | 71 | 0.117 | 1 |
RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | GO:0000781 | Not Cancer Driver | No | 287 | 0.116 | 1355 | 164 | 0.121 | 0 |
RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0000781 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
RPA1 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | GO:0000781 | Not Cancer Driver | No | 51 | 0.083 | 98 | 6 | 0.061 | 0 |
RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0000781 | Not Cancer Driver | No | 28 | 0.104 | 114 | 16 | 0.14 | 0 |
RPA4 | RPA4 | Q13156 | Replication protein A 30 kDa subunit | chrX | GO:0000781 | Not Cancer Driver | No | 66 | 0.253 | 58 | 15 | 0.259 | 0 |
RTEL1_ENST00000370018 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:0000781 | Not Cancer Driver | No | 144 | 0.118 | 474 | 64 | 0.135 | 14 |
SETX | SETX | Q7Z333 | Probable helicase senataxin | chr9 | GO:0000781 | Not Cancer Driver | No | 342 | 0.128 | 1240 | 156 | 0.126 | 20 |
SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0000781 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0000781 | Not Cancer Driver | No | 33 | 0.093 | 164 | 12 | 0.073 | 0 |
SLX4 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | GO:0000781 | Not Cancer Driver | No | 271 | 0.148 | 1573 | 232 | 0.147 | 0 |
SMC5 | SMC5 | Q8IY18 | Structural maintenance of chromosomes protein 5 | chr9 | GO:0000781 | Not Cancer Driver | No | 126 | 0.114 | 378 | 43 | 0.114 | 0 |
SMC6_ENST00000351948 | SMC6 | Q96SB8 | Structural maintenance of chromosomes protein 6 | chr2 | GO:0000781 | Not Cancer Driver | No | 128 | 0.117 | 458 | 57 | 0.124 | 0 |
SMCHD1 | SMCHD1 | A6NHR9 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | chr18 | GO:0000781 | Not Cancer Driver | No | 240 | 0.12 | 342 | 45 | 0.132 | 45 |
SMG6 | SMG6 | Q86US8 | Telomerase-binding protein EST1A | chr17 | GO:0000781 | Not Cancer Driver | No | 166 | 0.117 | 751 | 97 | 0.129 | 0 |
SP100_ENST00000264052 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | GO:0000781 | Not Cancer Driver | No | 136 | 0.155 | 680 | 101 | 0.149 | 0 |
SPO11 | SPO11 | Q9Y5K1 | Meiotic recombination protein SPO11 | chr20 | GO:0000781 | Not Cancer Driver | No | 59 | 0.149 | 26 | 5 | 0.192 | 0 |
SSB | SSB | P05455 | Lupus La protein | chr2 | GO:0000781 | Not Cancer Driver | No | 39 | 0.096 | 181 | 18 | 0.099 | 0 |
STN1 | STN1 | Q9H668 | CST complex subunit STN1 | chr10 | GO:0000781 | Not Cancer Driver | No | 41 | 0.111 | 27 | 2 | 0.074 | 2 |
TELO2 | TELO2 | Q9Y4R8 | Telomere length regulation protein TEL2 homolog | chr16 | GO:0000781 | Not Cancer Driver | No | 113 | 0.135 | 154 | 23 | 0.149 | 5 |
TEN1 | TEN1 | Q86WV5 | CST complex subunit TEN1 | chr17 | GO:0000781 | Not Cancer Driver | No | 6 | 0.049 | 8 | 4 | 0.5 | 0 |
TEP1 | TEP1 | Q99973 | Telomerase protein component 1 | chr14 | GO:0000781 | Not Cancer Driver | No | 332 | 0.126 | 396 | 67 | 0.169 | 0 |
TERB1_ENST00000558713 | TERB1 | Q8NA31 | Telomere repeats-binding bouquet formation protein 1 | chr16 | GO:0000781 | Not Cancer Driver | No | 33 | 0.045 | 201 | 14 | 0.07 | 0 |
TERB2 | TERB2 | Q8NHR7 | Telomere repeats-binding bouquet formation protein 2 | chr15 | GO:0000781 | Not Cancer Driver | No | 38 | 0.173 | 35 | 5 | 0.143 | 0 |
TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | GO:0000781 | Not Cancer Driver | No | 63 | 0.144 | 220 | 34 | 0.155 | 0 |
TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:0000781 | Not Cancer Driver | No | 33 | 0.061 | 361 | 20 | 0.055 | 0 |
TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:0000781 | Not Cancer Driver | No | 28 | 0.07 | 310 | 16 | 0.052 | 0 |
TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:0000781 | Census | Yes | 110 | 0.097 | 212 | 16 | 0.075 | 31 |
TFIP11_ENST00000407148 | TFIP11 | Q9UBB9 | Tuftelin-interacting protein 11 | chr22 | GO:0000781 | Not Cancer Driver | No | 87 | 0.104 | 331 | 39 | 0.118 | 0 |
THOC1 | THOC1 | Q96FV9 | THO complex subunit 1 | chr18 | GO:0000781 | Not Cancer Driver | No | 55 | 0.084 | 280 | 26 | 0.093 | 0 |
THOC2_ENST00000355725 | THOC2 | Q8NI27 | THO complex subunit 2 | chrX | GO:0000781 | Not Cancer Driver | No | 287 | 0.18 | 549 | 103 | 0.188 | 4 |
THOC3 | THOC3 | Q96J01 | THO complex subunit 3 | chr5 | GO:0000781 | Not Cancer Driver | No | 26 | 0.074 | 23 | 2 | 0.087 | 0 |
THOC5_ENST00000397872 | THOC5 | Q13769 | THO complex subunit 5 homolog | chr22 | GO:0000781 | Not Cancer Driver | No | 88 | 0.129 | 173 | 25 | 0.145 | 0 |
THOC6 | THOC6 | Q86W42 | THO complex subunit 6 homolog | chr16 | GO:0000781 | Not Cancer Driver | No | 49 | 0.144 | 16 | 4 | 0.25 | 1 |
THOC7 | THOC7 | Q6I9Y2 | THO complex subunit 7 homolog | chr3 | GO:0000781 | Not Cancer Driver | No | 26 | 0.127 | 63 | 5 | 0.079 | 0 |
TINF2 | TINF2 | Q9BSI4 | TERF1-interacting nuclear factor 2 | chr14 | GO:0000781 | Not Cancer Driver | No | 38 | 0.084 | 190 | 17 | 0.089 | 4 |
TNKS | TNKS | O95271 | Poly [ADP-ribose] polymerase tankyrase-1 | chr8 | GO:0000781 | Not Cancer Driver | No | 163 | 0.123 | 480 | 59 | 0.123 | 0 |
TNKS2 | TNKS2 | Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | chr10 | GO:0000781 | Not Cancer Driver | No | 117 | 0.1 | 255 | 24 | 0.094 | 0 |
TOX4_ENST00000448790 | TOX4 | O94842 | TOX high mobility group box family member 4 | chr14 | GO:0000781 | Not Cancer Driver | No | 69 | 0.111 | 562 | 62 | 0.11 | 0 |
TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | GO:0000781 | Not Cancer Driver | No | 227 | 0.115 | 1632 | 190 | 0.116 | 0 |
UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0000781 | Not Cancer Driver | No | 146 | 0.129 | 329 | 36 | 0.109 | 0 |
WDR82 | WDR82 | Q6UXN9 | WD repeat-containing protein 82 | chr3 | GO:0000781 | Not Cancer Driver | No | 35 | 0.112 | 0 | 0 | 0.0 | 0 |
WRAP53 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:0000781 | Not Cancer Driver | No | 66 | 0.12 | 232 | 29 | 0.125 | 4 |
WRN | WRN | Q14191 | Werner syndrome ATP-dependent helicase | chr8 | GO:0000781 | Census, Compendium | Yes | 164 | 0.115 | 373 | 41 | 0.11 | 2 |
WRNIP1 | WRNIP1 | Q96S55 | ATPase WRNIP1 | chr6 | GO:0000781 | Not Cancer Driver | No | 50 | 0.075 | 292 | 7 | 0.024 | 0 |
XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0000781 | Not Cancer Driver | No | 85 | 0.134 | 426 | 53 | 0.124 | 1 |
XRCC3_ENST00000352127 | XRCC3 | O43542 | DNA repair protein XRCC3 | chr14 | GO:0000781 | Not Cancer Driver | No | 24 | 0.069 | 35 | 2 | 0.057 | 1 |
XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0000781 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0000781 | Not Cancer Driver | No | 66 | 0.108 | 140 | 12 | 0.086 | 0 |
ZBTB10 | ZBTB10 | Q96DT7 | Zinc finger and BTB domain-containing protein 10 | chr8 | GO:0000781 | Not Cancer Driver | No | 59 | 0.068 | 531 | 32 | 0.06 | 0 |
ZBTB48 | ZBTB48 | P10074 | Telomere zinc finger-associated protein | chr1 | GO:0000781 | Not Cancer Driver | No | 53 | 0.077 | 237 | 16 | 0.068 | 0 |
ZNF827 | ZNF827 | Q17R98 | Zinc finger protein 827 | chr4 | GO:0000781 | Not Cancer Driver | No | 158 | 0.146 | 754 | 123 | 0.163 | 0 |
ZSCAN4_ENST00000612521 | ZSCAN4 | Q8NAM6 | Zinc finger and SCAN domain-containing protein 4 | chr19 | GO:0000781 | Not Cancer Driver | No | 108 | 0.249 | 249 | 58 | 0.233 | 0 |