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Total number of protein in "GO:0000775" GO term:  58

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AURKC AURKC Q9UQB9 Aurora kinase C chr19 GO:0000775 Not Cancer Driver No 70 0.227 43 5 0.116 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 GO:0000775 Not Cancer Driver No 20 0.141 49 6 0.122 0
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 GO:0000775 Not Cancer Driver No 31 0.168 154 25 0.162 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0000775 Not Cancer Driver No 23 0.126 119 18 0.151 0
CDCA5 CDCA5 Q96FF9 Sororin chr11 GO:0000775 Not Cancer Driver No 32 0.127 211 26 0.123 0
CDCA8_ENST00000327331 CDCA8 Q53HL2 Borealin chr1 GO:0000775 Not Cancer Driver No 23 0.082 170 13 0.076 0
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 GO:0000775 Not Cancer Driver No 15 0.107 50 4 0.08 0
CENPB CENPB P07199 Major centromere autoantigen B chr20 GO:0000775 Not Cancer Driver No 64 0.107 374 39 0.104 0
CENPE CENPE Q02224 Centromere-associated protein E chr4 GO:0000775 Not Cancer Driver No 343 0.127 1620 228 0.141 2
CENPF CENPF P49454 Centromere protein F chr1 GO:0000775 Not Cancer Driver No 387 0.124 2136 260 0.122 0
CENPL_ENST00000367710 CENPL Q8N0S6 Centromere protein L chr1 GO:0000775 Not Cancer Driver No 40 0.116 27 7 0.259 0
CENPP CENPP Q6IPU0 Centromere protein P chr9 GO:0000775 Not Cancer Driver No 30 0.104 40 4 0.1 0
CENPT_ENST00000440851 CENPT Q96BT3 Centromere protein T chr16 GO:0000775 Not Cancer Driver No 59 0.105 468 55 0.118 0
CENPW_ENST00000368328 CENPW Q5EE01 Centromere protein W chr6 GO:0000775 Not Cancer Driver No 9 0.102 5 1 0.2 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 GO:0000775 Census, Compendium Yes 151 0.208 481 83 0.173 1
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 GO:0000775 Census, Compendium Yes 106 0.143 549 81 0.148 0
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0000775 Census, Compendium Yes 194 0.213 371 59 0.159 16
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:0000775 Not Cancer Driver No 28 0.071 41 4 0.098 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0000775 Not Cancer Driver No 124 0.196 327 70 0.214 3
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0000775 Not Cancer Driver No 78 0.093 227 25 0.11 0
HJURP HJURP Q8NCD3 Holliday junction recognition protein chr2 GO:0000775 Not Cancer Driver No 108 0.144 572 85 0.149 0
INCENP INCENP Q9NQS7 Inner centromere protein chr11 GO:0000775 Not Cancer Driver No 107 0.117 856 103 0.12 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0000775 Census Yes 97 0.159 327 47 0.144 0
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 GO:0000775 Not Cancer Driver No 110 0.152 337 63 0.187 0
MIS18A MIS18A Q9NYP9 Protein Mis18-alpha chr21 GO:0000775 Not Cancer Driver No 20 0.086 15 1 0.067 0
MIS18BP1 MIS18BP1 Q6P0N0 Mis18-binding protein 1 chr14 GO:0000775 Not Cancer Driver No 125 0.11 847 96 0.113 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 GO:0000775 Not Cancer Driver No 80 0.125 313 45 0.144 0
NGDN NGDN Q8NEJ9 Neuroguidin chr14 GO:0000775 Not Cancer Driver No 42 0.133 195 29 0.149 0
NUF2_ENST00000367900 NUF2 Q9BZD4 Kinetochore protein Nuf2 chr1 GO:0000775 Not Cancer Driver No 97 0.209 74 20 0.27 0
OIP5 OIP5 O43482 Protein Mis18-beta chr15 GO:0000775 Not Cancer Driver No 31 0.135 65 7 0.108 0
PDS5A PDS5A Q29RF7 Sister chromatid cohesion protein PDS5 homolog A chr4 GO:0000775 Not Cancer Driver No 150 0.112 295 34 0.115 0
PDS5B PDS5B Q9NTI5 Sister chromatid cohesion protein PDS5 homolog B chr13 GO:0000775 Not Cancer Driver No 174 0.12 455 61 0.134 0
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0000775 Not Cancer Driver No 778 0.191 413 81 0.196 93
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0000775 Not Cancer Driver No 41 0.133 12 1 0.083 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 GO:0000775 Not Cancer Driver No 37 0.12 12 0 0.0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0000775 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:0000775 Not Cancer Driver No 55 0.113 93 5 0.054 0
PPP2R5C_ENST00000334743 PPP2R5C Q13362 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform chr14 GO:0000775 Not Cancer Driver No 65 0.124 89 16 0.18 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0000775 Census, Compendium Yes 115 0.182 421 74 0.176 3
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 GO:0000775 Not Cancer Driver No 57 0.102 360 39 0.108 1
SGO2 SGO2 Q562F6 Shugoshin 2 chr2 GO:0000775 Not Cancer Driver No 164 0.13 1025 134 0.131 0
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX GO:0000775 Census, Compendium Yes 200 0.162 717 114 0.159 21
SMC1B SMC1B Q8NDV3 Structural maintenance of chromosomes protein 1B chr22 GO:0000775 Not Cancer Driver No 174 0.141 332 48 0.145 0
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 GO:0000775 Not Cancer Driver No 149 0.122 605 70 0.116 0
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 GO:0000775 Not Cancer Driver No 175 0.136 539 55 0.102 0
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0000775 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0000775 Not Cancer Driver No 128 0.117 458 57 0.124 0
STAG1 STAG1 Q8WVM7 Cohesin subunit SA-1 chr3 GO:0000775 Census Yes 226 0.18 391 66 0.169 8
STAG2_ENST00000371157 STAG2 Q8N3U4 Cohesin subunit SA-2 chrX GO:0000775 Census, Compendium Yes 179 0.145 330 46 0.139 3
STAG3_ENST00000426455 STAG3 Q9UJ98 Cohesin subunit SA-3 chr7 GO:0000775 Not Cancer Driver No 153 0.125 388 59 0.152 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0000775 Not Cancer Driver No 59 0.143 15 1 0.067 0
SUV39H2 SUV39H2 Q9H5I1 Histone-lysine N-methyltransferase SUV39H2 chr10 GO:0000775 Not Cancer Driver No 39 0.095 23 1 0.043 0
SYCP1_ENST00000618516 SYCP1 Q15431 Synaptonemal complex protein 1 chr1 GO:0000775 Not Cancer Driver No 207 0.212 602 124 0.206 0
SYCP3_ENST00000392924 SYCP3 Q8IZU3 Synaptonemal complex protein 3 chr12 GO:0000775 Not Cancer Driver No 30 0.127 124 12 0.097 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0000775 Compendium Yes 150 0.098 508 59 0.116 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0000775 Not Cancer Driver No 89 0.127 243 28 0.115 0
WAPL_ENST00000618527 WAPL Q7Z5K2 Wings apart-like protein homolog chr10 GO:0000775 Not Cancer Driver No 140 0.118 621 68 0.11 0
ZNF330 ZNF330 Q9Y3S2 Zinc finger protein 330 chr4 GO:0000775 Not Cancer Driver No 44 0.138 127 19 0.15 0