Total number of protein in "GO:0000422" GO term: 47
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMBRA1_ENST00000458649 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:0000422 | Not Cancer Driver | No | 173 | 0.133 | 788 | 103 | 0.131 | 0 |
| ARFIP2_ENST00000254584 | ARFIP2 | P53365 | Arfaptin-2 | chr11 | GO:0000422 | Not Cancer Driver | No | 37 | 0.109 | 144 | 15 | 0.104 | 0 |
| ATG12 | ATG12 | O94817 | Ubiquitin-like protein ATG12 | chr5 | GO:0000422 | Not Cancer Driver | No | 15 | 0.107 | 60 | 8 | 0.133 | 0 |
| ATG13_ENST00000359513 | ATG13 | O75143 | Autophagy-related protein 13 | chr11 | GO:0000422 | Not Cancer Driver | No | 55 | 0.106 | 205 | 27 | 0.132 | 0 |
| ATG14 | ATG14 | Q6ZNE5 | Beclin 1-associated autophagy-related key regulator | chr14 | GO:0000422 | Not Cancer Driver | No | 48 | 0.098 | 209 | 24 | 0.115 | 0 |
| ATG2A | ATG2A | Q2TAZ0 | Autophagy-related protein 2 homolog A | chr11 | GO:0000422 | Not Cancer Driver | No | 228 | 0.118 | 887 | 124 | 0.14 | 0 |
| ATG2B | ATG2B | Q96BY7 | Autophagy-related protein 2 homolog B | chr14 | GO:0000422 | Not Cancer Driver | No | 264 | 0.127 | 679 | 111 | 0.163 | 0 |
| ATG3 | ATG3 | Q9NT62 | Ubiquitin-like-conjugating enzyme ATG3 | chr3 | GO:0000422 | Not Cancer Driver | No | 29 | 0.092 | 110 | 9 | 0.082 | 0 |
| ATG4B | ATG4B | Q9Y4P1 | Cysteine protease ATG4B | chr2 | GO:0000422 | Not Cancer Driver | No | 34 | 0.087 | 13 | 2 | 0.154 | 0 |
| ATG4D | ATG4D | Q86TL0 | Cysteine protease ATG4D | chr19 | GO:0000422 | Not Cancer Driver | No | 70 | 0.148 | 106 | 12 | 0.113 | 0 |
| ATG5_ENST00000343245 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | GO:0000422 | Not Cancer Driver | No | 40 | 0.145 | 25 | 6 | 0.24 | 1 |
| ATG7 | ATG7 | O95352 | Ubiquitin-like modifier-activating enzyme ATG7 | chr3 | GO:0000422 | Compendium | Yes | 77 | 0.11 | 53 | 8 | 0.151 | 6 |
| ATG9A | ATG9A | Q7Z3C6 | Autophagy-related protein 9A | chr2 | GO:0000422 | Not Cancer Driver | No | 92 | 0.11 | 252 | 30 | 0.119 | 0 |
| ATG9B | ATG9B | Q674R7 | Autophagy-related protein 9B | chr7 | GO:0000422 | Not Cancer Driver | No | 92 | 0.1 | 368 | 43 | 0.117 | 0 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0000422 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| C5orf51 | RIMOC1 | A6NDU8 | RAB7A-interacting MON1-CCZ1 complex subunit 1 | chr5 | GO:0000422 | Not Cancer Driver | No | 31 | 0.105 | 15 | 3 | 0.2 | 0 |
| CISD2 | CISD2 | Q8N5K1 | CDGSH iron-sulfur domain-containing protein 2 | chr4 | GO:0000422 | Not Cancer Driver | No | 11 | 0.081 | 7 | 0 | 0.0 | 0 |
| CTSK | CTSK | P43235 | Cathepsin K | chr1 | GO:0000422 | Not Cancer Driver | No | 36 | 0.109 | 24 | 4 | 0.167 | 6 |
| FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | GO:0000422 | Not Cancer Driver | No | 75 | 0.144 | 243 | 38 | 0.156 | 1 |
| FIS1 | FIS1 | Q9Y3D6 | Mitochondrial fission 1 protein | chr7 | GO:0000422 | Not Cancer Driver | No | 25 | 0.164 | 6 | 0 | 0.0 | 0 |
| FUNDC1 | FUNDC1 | Q8IVP5 | FUN14 domain-containing protein 1 | chrX | GO:0000422 | Not Cancer Driver | No | 16 | 0.103 | 24 | 2 | 0.083 | 0 |
| FUNDC2 | FUNDC2 | Q9BWH2 | FUN14 domain-containing protein 2 | chrX | GO:0000422 | Not Cancer Driver | No | 28 | 0.148 | 34 | 3 | 0.088 | 0 |
| GABARAP | GABARAP | O95166 | Gamma-aminobutyric acid receptor-associated protein | chr17 | GO:0000422 | Not Cancer Driver | No | 9 | 0.077 | 11 | 0 | 0.0 | 0 |
| GABARAPL1_ENST00000545887 | GABARAPL1 | Q9H0R8 | Gamma-aminobutyric acid receptor-associated protein-like 1 | chr12 | GO:0000422 | Not Cancer Driver | No | 19 | 0.162 | 10 | 1 | 0.1 | 0 |
| GABARAPL2 | GABARAPL2 | P60520 | Gamma-aminobutyric acid receptor-associated protein-like 2 | chr16 | GO:0000422 | Not Cancer Driver | No | 11 | 0.094 | 2 | 1 | 0.5 | 0 |
| LRBA | LRBA | P50851 | Lipopolysaccharide-responsive and beige-like anchor protein | chr4 | GO:0000422 | Not Cancer Driver | No | 350 | 0.122 | 709 | 82 | 0.116 | 1 |
| MAP1LC3A_ENST00000397709 | MAP1LC3A | Q9H492 | Microtubule-associated proteins 1A/1B light chain 3A | chr20 | GO:0000422 | Not Cancer Driver | No | 22 | 0.182 | 24 | 1 | 0.042 | 0 |
| MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | GO:0000422 | Not Cancer Driver | No | 10 | 0.08 | 17 | 1 | 0.059 | 0 |
| MAP1LC3B2 | MAP1LC3B2 | A6NCE7 | Microtubule-associated proteins 1A/1B light chain 3 beta 2 | chr12 | GO:0000422 | Not Cancer Driver | No | 19 | 0.152 | 17 | 7 | 0.412 | 0 |
| MAP1LC3C | MAP1LC3C | Q9BXW4 | Microtubule-associated proteins 1A/1B light chain 3C | chr1 | GO:0000422 | Not Cancer Driver | No | 32 | 0.218 | 31 | 5 | 0.161 | 0 |
| MARK2 | MARK2 | Q7KZI7 | Serine/threonine-protein kinase MARK2 | chr11 | GO:0000422 | Compendium | Yes | 124 | 0.157 | 445 | 70 | 0.157 | 0 |
| PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | GO:0000422 | Not Cancer Driver | No | 31 | 0.104 | 26 | 4 | 0.154 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0000422 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0000422 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | GO:0000422 | Not Cancer Driver | No | 202 | 0.127 | 578 | 75 | 0.13 | 0 |
| RETREG1 | RETREG1 | Q9H6L5 | Reticulophagy regulator 1 | chr5 | GO:0000422 | Not Cancer Driver | No | 48 | 0.097 | 245 | 21 | 0.086 | 0 |
| SLC25A46 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | GO:0000422 | Not Cancer Driver | No | 37 | 0.089 | 96 | 2 | 0.021 | 4 |
| SPATA18 | SPATA18 | Q8TC71 | Mitochondria-eating protein | chr4 | GO:0000422 | Not Cancer Driver | No | 129 | 0.24 | 222 | 49 | 0.221 | 0 |
| SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | GO:0000422 | Not Cancer Driver | No | 54 | 0.123 | 267 | 32 | 0.12 | 30 |
| TAZ_ENST00000612460 | TAFAZZIN | Q16635 | Tafazzin | chrX | GO:0000422 | Not Cancer Driver | No | 33 | 0.126 | 12 | 0 | 0.0 | 10 |
| ULK1 | ULK1 | O75385 | Serine/threonine-protein kinase ULK1 | chr12 | GO:0000422 | Not Cancer Driver | No | 142 | 0.135 | 588 | 77 | 0.131 | 0 |
| ULK2_ENST00000361658 | ULK2 | Q8IYT8 | Serine/threonine-protein kinase ULK2 | chr17 | GO:0000422 | Not Cancer Driver | No | 132 | 0.127 | 519 | 84 | 0.162 | 0 |
| USP30 | USP30 | Q70CQ3 | Ubiquitin carboxyl-terminal hydrolase 30 | chr12 | GO:0000422 | Not Cancer Driver | No | 76 | 0.147 | 136 | 26 | 0.191 | 0 |
| WDR45B | WDR45B | Q5MNZ6 | WD repeat domain phosphoinositide-interacting protein 3 | chr17 | GO:0000422 | Not Cancer Driver | No | 48 | 0.14 | 8 | 1 | 0.125 | 0 |
| WDR45_ENST00000634944 | WDR45 | Q9Y484 | WD repeat domain phosphoinositide-interacting protein 4 | chrX | GO:0000422 | Compendium | Yes | 62 | 0.172 | 10 | 1 | 0.1 | 0 |
| WIPI1 | WIPI1 | Q5MNZ9 | WD repeat domain phosphoinositide-interacting protein 1 | chr17 | GO:0000422 | Not Cancer Driver | No | 45 | 0.101 | 113 | 9 | 0.08 | 0 |
| WIPI2 | WIPI2 | Q9Y4P8 | WD repeat domain phosphoinositide-interacting protein 2 | chr7 | GO:0000422 | Not Cancer Driver | No | 64 | 0.141 | 68 | 5 | 0.074 | 1 |