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Total number of protein in "GO:0000287" GO term:  217

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AASDHPPT AASDHPPT Q9NRN7 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase chr11 GO:0000287 Not Cancer Driver No 52 0.168 27 2 0.074 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0000287 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0000287 Census, Compendium Yes 171 0.145 641 70 0.109 0
ADCY10 ADCY10 Q96PN6 Adenylate cyclase type 10 chr1 GO:0000287 Not Cancer Driver No 249 0.155 24 4 0.167 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0000287 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADPRH ADPRH P54922 ADP-ribosylhydrolase ARH1 chr3 GO:0000287 Not Cancer Driver No 54 0.151 30 3 0.1 0
ADPRHL1 ADPRHL1 Q8NDY3 Inactive ADP-ribosyltransferase ARH2 chr13 GO:0000287 Not Cancer Driver No 52 0.147 32 7 0.219 0
ADPRHL2 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0000287 Not Cancer Driver No 32 0.088 49 4 0.082 1
ADSS ADSS2 P30520 Adenylosuccinate synthetase isozyme 2 chr1 GO:0000287 Not Cancer Driver No 49 0.107 48 4 0.083 0
ADSSL1_ENST00000330877 ADSS1 Q8N142 Adenylosuccinate synthetase isozyme 1 chr14 GO:0000287 Not Cancer Driver No 74 0.162 68 6 0.088 1
ALPI ALPI P09923 Intestinal-type alkaline phosphatase chr2 GO:0000287 Not Cancer Driver No 94 0.178 157 36 0.229 0
ALPP ALPP P05187 Alkaline phosphatase, placental type chr2 GO:0000287 Not Cancer Driver No 120 0.224 161 40 0.248 0
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 GO:0000287 Not Cancer Driver No 30 0.166 4 2 0.5 2
ARL3 ARL3 P36405 ADP-ribosylation factor-like protein 3 chr10 GO:0000287 Not Cancer Driver No 16 0.088 0 0 0.0 2
ATP10A ATP10A O60312 Phospholipid-transporting ATPase VA chr15 GO:0000287 Not Cancer Driver No 366 0.244 408 100 0.245 0
ATP10B ATP10B O94823 Phospholipid-transporting ATPase VB chr5 GO:0000287 Not Cancer Driver No 310 0.212 333 66 0.198 0
ATP10D ATP10D Q9P241 Phospholipid-transporting ATPase VD chr4 GO:0000287 Not Cancer Driver No 253 0.177 235 45 0.191 0
ATP11A ATP11A P98196 Phospholipid-transporting ATPase IH chr13 GO:0000287 Not Cancer Driver No 171 0.151 77 17 0.221 0
ATP11B ATP11B Q9Y2G3 Phospholipid-transporting ATPase IF chr3 GO:0000287 Not Cancer Driver No 129 0.11 73 10 0.137 0
ATP11C ATP11C Q8NB49 Phospholipid-transporting ATPase IG chrX GO:0000287 Not Cancer Driver No 198 0.175 32 5 0.156 1
ATP4A ATP4A P20648 Potassium-transporting ATPase alpha chain 1 chr19 GO:0000287 Not Cancer Driver No 201 0.194 121 30 0.248 0
ATP8A1 ATP8A1 Q9Y2Q0 Phospholipid-transporting ATPase IA chr4 GO:0000287 Not Cancer Driver No 185 0.159 84 7 0.083 0
ATP8A2 ATP8A2 Q9NTI2 Phospholipid-transporting ATPase IB chr13 GO:0000287 Not Cancer Driver No 236 0.199 78 14 0.179 1
ATP8B1 ATP8B1 O43520 Phospholipid-transporting ATPase IC chr18 GO:0000287 Not Cancer Driver No 156 0.125 133 17 0.128 29
ATP8B2 ATP8B2 P98198 Phospholipid-transporting ATPase ID chr1 GO:0000287 Not Cancer Driver No 182 0.151 101 11 0.109 0
ATP8B3 ATP8B3 O60423 Phospholipid-transporting ATPase IK chr19 GO:0000287 Not Cancer Driver No 151 0.116 180 22 0.122 0
ATP8B4_ENST00000559829 ATP8B4 Q8TF62 Probable phospholipid-transporting ATPase IM chr15 GO:0000287 Not Cancer Driver No 242 0.203 102 27 0.265 0
ATP9A ATP9A O75110 Probable phospholipid-transporting ATPase IIA chr20 GO:0000287 Not Cancer Driver No 175 0.167 69 18 0.261 0
ATP9B ATP9B O43861 Probable phospholipid-transporting ATPase IIB chr18 GO:0000287 Not Cancer Driver No 145 0.126 111 9 0.081 0
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0000287 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0000287 Not Cancer Driver No 90 0.122 321 39 0.121 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 GO:0000287 Not Cancer Driver No 215 0.124 717 80 0.112 0
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 GO:0000287 Not Cancer Driver No 185 0.108 696 92 0.132 0
CDC42BPG CDC42BPG Q6DT37 Serine/threonine-protein kinase MRCK gamma chr11 GO:0000287 Not Cancer Driver No 166 0.107 736 79 0.107 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0000287 Not Cancer Driver No 24 0.081 0 0 0.0 0
CERK CERK Q8TCT0 Ceramide kinase chr22 GO:0000287 Not Cancer Driver No 56 0.104 48 5 0.104 0
CIB2 CIB2 O75838 Calcium and integrin-binding family member 2 chr15 GO:0000287 Not Cancer Driver No 25 0.134 7 0 0.0 5
CIB3 CIB3 Q96Q77 Calcium and integrin-binding family member 3 chr19 GO:0000287 Not Cancer Driver No 55 0.294 3 2 0.667 0
CIB4 CIB4 A0PJX0 Calcium and integrin-binding family member 4 chr2 GO:0000287 Not Cancer Driver No 36 0.195 0 0 0.0 0
CLYBL CLYBL Q8N0X4 Citramalyl-CoA lyase, mitochondrial chr13 GO:0000287 Not Cancer Driver No 48 0.141 0 0 0.0 0
COMT COMT P21964 Catechol O-methyltransferase chr22 GO:0000287 Not Cancer Driver No 21 0.077 5 0 0.0 0
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 GO:0000287 Not Cancer Driver No 14 0.082 88 9 0.102 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0000287 Not Cancer Driver No 159 0.158 222 39 0.176 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0000287 Not Cancer Driver No 114 0.129 264 22 0.083 1
DUT DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 GO:0000287 Not Cancer Driver No 19 0.075 128 8 0.062 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0000287 Not Cancer Driver No 46 0.116 143 17 0.119 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0000287 Not Cancer Driver No 77 0.128 294 39 0.133 0
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:0000287 Not Cancer Driver No 87 0.148 193 20 0.104 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0000287 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENDOV ENDOV Q8N8Q3 Endonuclease V chr17 GO:0000287 Not Cancer Driver No 28 0.099 43 3 0.07 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0000287 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENO2 ENO2 P09104 Gamma-enolase chr12 GO:0000287 Not Cancer Driver No 48 0.111 12 2 0.167 0
ENO3 ENO3 P13929 Beta-enolase chr17 GO:0000287 Not Cancer Driver No 46 0.106 26 1 0.038 2
ENO4 ENO4 A6NNW6 Enolase 4 chr10 GO:0000287 Not Cancer Driver No 13 0.021 197 4 0.02 0
ENOPH1 ENOPH1 Q9UHY7 Enolase-phosphatase E1 chr4 GO:0000287 Not Cancer Driver No 35 0.134 14 2 0.143 0
ENOSF1_ENST00000251101 ENOSF1 Q7L5Y1 Mitochondrial enolase superfamily member 1 chr18 GO:0000287 Not Cancer Driver No 62 0.14 25 2 0.08 0
EPHX2 EPHX2 P34913 Bifunctional epoxide hydrolase 2 chr8 GO:0000287 Not Cancer Driver No 78 0.141 26 3 0.115 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0000287 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0000287 Not Cancer Driver No 192 0.207 213 45 0.211 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 GO:0000287 Not Cancer Driver No 58 0.093 176 15 0.085 0
EYA2 EYA2 O00167 Eyes absent homolog 2 chr20 GO:0000287 Not Cancer Driver No 107 0.199 204 50 0.245 0
FAN1 FAN1 Q9Y2M0 Fanconi-associated nuclease 1 chr15 GO:0000287 Not Cancer Driver No 124 0.122 212 27 0.127 4
FARSB FARSB Q9NSD9 Phenylalanine--tRNA ligase beta subunit chr2 GO:0000287 Not Cancer Driver No 71 0.121 0 0 0.0 8
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0000287 Census Yes 35 0.092 111 11 0.099 0
FIGNL1 FIGNL1 Q6PIW4 Fidgetin-like protein 1 chr7 GO:0000287 Not Cancer Driver No 75 0.111 224 23 0.103 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0000287 Not Cancer Driver No 79 0.12 548 64 0.117 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0000287 Not Cancer Driver No 73 0.115 167 18 0.108 3
GEM GEM P55040 GTP-binding protein GEM chr8 GO:0000287 Not Cancer Driver No 64 0.216 96 22 0.229 0
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:0000287 Not Cancer Driver No 109 0.12 339 52 0.153 0
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0000287 Not Cancer Driver No 66 0.177 104 21 0.202 2
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 GO:0000287 Not Cancer Driver No 52 0.147 11 3 0.273 0
GSS_ENST00000216951 GSS P48637 Glutathione synthetase chr20 GO:0000287 Not Cancer Driver No 61 0.129 49 6 0.122 14
GTPBP10 GTPBP10 A4D1E9 GTP-binding protein 10 chr7 GO:0000287 Not Cancer Driver No 50 0.129 52 4 0.077 0
HACL1 HACL1 Q9UJ83 2-hydroxyacyl-CoA lyase 1 chr3 GO:0000287 Not Cancer Driver No 70 0.121 28 4 0.143 0
HMGCL HMGCL P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial chr1 GO:0000287 Not Cancer Driver No 17 0.052 8 2 0.25 19
HPGDS HPGDS O60760 Hematopoietic prostaglandin D synthase chr4 GO:0000287 Not Cancer Driver No 34 0.171 0 0 0.0 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0000287 Not Cancer Driver No 22 0.101 3 0 0.0 62
ICK CILK1 Q9UPZ9 Serine/threonine-protein kinase ICK chr6 GO:0000287 Not Cancer Driver No 73 0.116 366 44 0.12 3
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 GO:0000287 Census, Compendium Yes 553 1.336 37 3 0.081 0
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 GO:0000287 Census, Compendium Yes 74 0.164 59 1 0.017 7
IDH3A IDH3A P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial chr15 GO:0000287 Not Cancer Driver No 41 0.112 47 11 0.234 0
IDH3B_ENST00000380843 IDH3B O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial chr20 GO:0000287 Not Cancer Driver No 32 0.083 49 3 0.061 1
IDH3G IDH3G P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial chrX GO:0000287 Not Cancer Driver No 48 0.122 77 9 0.117 0
ILVBL ILVBL A1L0T0 2-hydroxyacyl-CoA lyase 2 chr19 GO:0000287 Not Cancer Driver No 86 0.136 30 1 0.033 0
IMPA1_ENST00000256108 IMPA1 P29218 Inositol monophosphatase 1 chr8 GO:0000287 Not Cancer Driver No 36 0.13 3 0 0.0 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0000287 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRAK4_ENST00000551736 IRAK4 Q9NWZ3 Interleukin-1 receptor-associated kinase 4 chr12 GO:0000287 Not Cancer Driver No 68 0.148 116 20 0.172 2
ITPK1 ITPK1 Q13572 Inositol-tetrakisphosphate 1-kinase chr14 GO:0000287 Not Cancer Driver No 74 0.179 24 1 0.042 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0000287 Census, Compendium Yes 161 0.142 788 100 0.127 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0000287 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0000287 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0000287 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0000287 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K6 MAP3K6 O95382 Mitogen-activated protein kinase kinase kinase 6 chr1 GO:0000287 Not Cancer Driver No 108 0.084 390 31 0.079 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0000287 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP3K8_ENST00000542547 MAP3K8 P41279 Mitogen-activated protein kinase kinase kinase 8 chr10 GO:0000287 Not Cancer Driver No 58 0.124 109 10 0.092 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 GO:0000287 Not Cancer Driver No 31 0.084 63 5 0.079 0
MARK1_ENST00000366917 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 GO:0000287 Not Cancer Driver No 161 0.203 454 108 0.238 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 GO:0000287 Compendium Yes 124 0.157 445 70 0.157 0
MAST1 MAST1 Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 chr19 GO:0000287 Not Cancer Driver No 204 0.13 1078 119 0.11 1
MAST2 MAST2 Q6P0Q8 Microtubule-associated serine/threonine-protein kinase 2 chr1 GO:0000287 Not Cancer Driver No 187 0.104 1326 133 0.1 0
MAST3 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 GO:0000287 Not Cancer Driver No 169 0.129 783 100 0.128 0
MAST4 MAST4 O15021 Microtubule-associated serine/threonine-protein kinase 4 chr5 GO:0000287 Not Cancer Driver No 317 0.121 2099 256 0.122 0
MORC2 MORC2 Q9Y6X9 ATPase MORC2 chr22 GO:0000287 Not Cancer Driver No 125 0.121 523 69 0.132 16
MOV10L1_ENST00000545383 MOV10L1 Q9BXT6 RNA helicase Mov10l1 chr22 GO:0000287 Not Cancer Driver No 184 0.152 178 21 0.118 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0000287 Census Yes 92 0.099 37 4 0.108 70
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0000287 Census Yes 154 0.113 386 41 0.106 6
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 GO:0000287 Not Cancer Driver No 57 0.14 47 9 0.191 0
MTHFD2 MTHFD2 P13995 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial chr2 GO:0000287 Not Cancer Driver No 39 0.111 39 3 0.077 0
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 GO:0000287 Not Cancer Driver No 73 0.125 136 22 0.162 1
MVK MVK Q03426 Mevalonate kinase chr12 GO:0000287 Not Cancer Driver No 50 0.126 25 0 0.0 38
NEK6_ENST00000545174 NEK6 Q9HC98 Serine/threonine-protein kinase Nek6 chr9 GO:0000287 Not Cancer Driver No 31 0.099 36 0 0.0 0
NIM1K NIM1K Q8IY84 Serine/threonine-protein kinase NIM1 chr5 GO:0000287 Not Cancer Driver No 73 0.167 126 21 0.167 0
NLK NLK Q9UBE8 Serine/threonine-protein kinase NLK chr17 GO:0000287 Not Cancer Driver No 54 0.102 152 20 0.132 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0000287 Not Cancer Driver No 205 0.2 15 2 0.133 3
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 GO:0000287 Not Cancer Driver No 11 0.072 10 0 0.0 0
NT5C1A NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 GO:0000287 Not Cancer Driver No 86 0.234 95 16 0.168 0
NT5C1B NT5C1B Q96P26 Cytosolic 5'-nucleotidase 1B chr2 GO:0000287 Not Cancer Driver No 136 0.223 253 58 0.229 0
NT5C3A NT5C3A Q9H0P0 Cytosolic 5'-nucleotidase 3A chr7 GO:0000287 Compendium Yes 44 0.131 0 0 0.0 8
NT5C3B NT5C3B Q969T7 7-methylguanosine phosphate-specific 5'-nucleotidase chr17 GO:0000287 Not Cancer Driver No 25 0.083 2 0 0.0 0
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0000287 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0000287 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT18 NUDT18 Q6ZVK8 8-oxo-dGDP phosphatase NUDT18 chr8 GO:0000287 Not Cancer Driver No 22 0.068 39 3 0.077 0
NUDT19 NUDT19 A8MXV4 Acyl-coenzyme A diphosphatase NUDT19 chr19 GO:0000287 Not Cancer Driver No 27 0.072 131 5 0.038 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 GO:0000287 Not Cancer Driver No 22 0.128 38 5 0.132 0
NUDT5_ENST00000537776 NUDT5 Q9UKK9 ADP-sugar pyrophosphatase chr10 GO:0000287 Not Cancer Driver No 27 0.123 90 11 0.122 0
NUDT7 NUDT7 P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 chr16 GO:0000287 Not Cancer Driver No 45 0.189 42 4 0.095 0
NUDT8 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 GO:0000287 Not Cancer Driver No 22 0.093 69 10 0.145 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0000287 Not Cancer Driver No 114 0.119 131 17 0.13 60
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0000287 Not Cancer Driver No 69 0.131 208 29 0.139 0
PAPOLA PAPOLA P51003 Poly(A) polymerase alpha chr14 GO:0000287 Not Cancer Driver No 97 0.13 293 28 0.096 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0000287 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:0000287 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0000287 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDXK PDXK O00764 Pyridoxal kinase chr21 GO:0000287 Not Cancer Driver No 27 0.087 47 6 0.128 2
PDXP PDXP Q96GD0 Chronophin chr22 GO:0000287 Not Cancer Driver No 14 0.047 38 4 0.105 0
PGM1_ENST00000371084 PGM1 P36871 Phosphoglucomutase-1 chr1 GO:0000287 Not Cancer Driver No 62 0.11 31 3 0.097 13
PGM2 PGM2 Q96G03 Phosphopentomutase chr4 GO:0000287 Not Cancer Driver No 79 0.129 108 13 0.12 0
PGM3_ENST00000513973 PGM3 O95394 Phosphoacetylglucosamine mutase chr6 GO:0000287 Not Cancer Driver No 78 0.144 77 8 0.104 7
PGM5 PGM5 Q15124 Phosphoglucomutase-like protein 5 chr9 GO:0000287 Not Cancer Driver No 165 0.291 54 4 0.074 0
PGP PGP A6NDG6 Glycerol-3-phosphate phosphatase chr16 GO:0000287 Not Cancer Driver No 10 0.031 21 0 0.0 0
PI4K2A PI4K2A Q9BTU6 Phosphatidylinositol 4-kinase type 2-alpha chr10 GO:0000287 Not Cancer Driver No 43 0.09 129 6 0.047 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0000287 Not Cancer Driver No 54 0.084 209 11 0.053 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0000287 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 GO:0000287 Not Cancer Driver No 112 0.195 26 5 0.192 101
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:0000287 Not Cancer Driver No 78 0.147 58 13 0.224 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0000287 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0000287 Not Cancer Driver No 43 0.135 92 13 0.141 0
PLSCR3 PLSCR3 Q9NRY6 Phospholipid scramblase 3 chr17 GO:0000287 Not Cancer Driver No 30 0.102 62 5 0.081 0
PPA1 PPA1 Q15181 Inorganic pyrophosphatase chr10 GO:0000287 Not Cancer Driver No 31 0.107 24 0 0.0 0
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 GO:0000287 Not Cancer Driver No 49 0.147 71 9 0.127 9
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:0000287 Not Cancer Driver No 60 0.157 134 24 0.179 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 GO:0000287 Not Cancer Driver No 65 0.136 243 31 0.128 0
PPM1N PPM1N Q8N819 Probable protein phosphatase 1N chr19 GO:0000287 Not Cancer Driver No 31 0.072 152 7 0.046 0
PRIM1 PRIM1 P49642 DNA primase small subunit chr12 GO:0000287 Not Cancer Driver No 31 0.074 22 1 0.045 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0000287 Census Yes 53 0.151 24 0 0.0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 GO:0000287 Not Cancer Driver No 50 0.142 26 6 0.231 4
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX GO:0000287 Not Cancer Driver No 50 0.157 0 0 0.0 14
PRPS1L1_ENST00000638645 PRPS1L1 P21108 Ribose-phosphate pyrophosphokinase 3 chr7 GO:0000287 Not Cancer Driver No 83 0.261 0 0 0.0 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX GO:0000287 Not Cancer Driver No 56 0.176 4 1 0.25 0
PRPSAP2 PRPSAP2 O60256 Phosphoribosyl pyrophosphate synthase-associated protein 2 chr17 GO:0000287 Not Cancer Driver No 54 0.146 19 3 0.158 0
PRTFDC1 PRTFDC1 Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 chr10 GO:0000287 Not Cancer Driver No 29 0.129 3 0 0.0 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 GO:0000287 Not Cancer Driver No 44 0.196 21 6 0.286 3
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0000287 Not Cancer Driver No 20 0.093 14 1 0.071 0
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 GO:0000287 Not Cancer Driver No 15 0.082 9 0 0.0 0
REXO2 REXO2 Q9Y3B8 Oligoribonuclease, mitochondrial chr11 GO:0000287 Not Cancer Driver No 19 0.08 43 4 0.093 0
RHEB RHEB Q15382 GTP-binding protein Rheb chr7 GO:0000287 Not Cancer Driver No 30 0.163 0 0 0.0 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 GO:0000287 Not Cancer Driver No 33 0.115 124 20 0.161 2
RP2 RP2 O75695 Protein XRP2 chrX GO:0000287 Not Cancer Driver No 45 0.129 28 6 0.214 10
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0000287 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0000287 Not Cancer Driver No 133 0.181 91 15 0.165 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0000287 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0000287 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0000287 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0000287 Not Cancer Driver No 180 0.242 136 36 0.265 0
RRAGC RRAGC Q9HB90 Ras-related GTP-binding protein C chr1 GO:0000287 Compendium Yes 29 0.073 61 1 0.016 0
S100P S100P P25815 Protein S100-P chr4 GO:0000287 Not Cancer Driver No 7 0.074 3 1 0.333 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0000287 Not Cancer Driver No 61 0.128 220 31 0.141 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0000287 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 GO:0000287 Not Cancer Driver No 94 0.102 525 56 0.107 0
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 GO:0000287 Not Cancer Driver No 143 0.108 964 107 0.111 1
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0000287 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNRK SNRK Q9NRH2 SNF-related serine/threonine-protein kinase chr3 GO:0000287 Not Cancer Driver No 82 0.107 368 47 0.128 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0000287 Not Cancer Driver No 47 0.122 25 2 0.08 0
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 GO:0000287 Not Cancer Driver No 73 0.111 329 32 0.097 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 GO:0000287 Not Cancer Driver No 78 0.113 343 46 0.134 0
SRR SRR Q9GZT4 Serine racemase chr17 GO:0000287 Not Cancer Driver No 40 0.118 32 6 0.188 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0000287 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX GO:0000287 Not Cancer Driver No 62 0.149 119 18 0.151 0
STK38 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 GO:0000287 Not Cancer Driver No 57 0.123 77 6 0.078 0
STK38L STK38L Q9Y2H1 Serine/threonine-protein kinase 38-like chr12 GO:0000287 Not Cancer Driver No 51 0.11 86 12 0.14 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0000287 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0000287 Not Cancer Driver No 70 0.144 231 30 0.13 0
SUCLA2 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 GO:0000287 Not Cancer Driver No 51 0.11 46 6 0.13 3
SUCLG2_ENST00000307227 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 GO:0000287 Not Cancer Driver No 48 0.111 12 2 0.167 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0000287 Not Cancer Driver No 75 0.183 185 31 0.168 0
TDP2 TDP2 O95551 Tyrosyl-DNA phosphodiesterase 2 chr6 GO:0000287 Not Cancer Driver No 55 0.152 80 10 0.125 0
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0000287 Not Cancer Driver No 31 0.145 73 6 0.082 0
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0000287 Not Cancer Driver No 32 0.107 22 2 0.091 1
THTPA THTPA Q9BU02 Thiamine-triphosphatase chr14 GO:0000287 Not Cancer Driver No 19 0.083 56 4 0.071 0
TKT_ENST00000462138 TKT P29401 Transketolase chr3 GO:0000287 Not Cancer Driver No 66 0.106 86 7 0.081 1
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0000287 Compendium Yes 150 0.098 508 59 0.116 0
TPPP TPPP O94811 Tubulin polymerization-promoting protein chr5 GO:0000287 Not Cancer Driver No 33 0.151 149 21 0.141 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0000287 Not Cancer Driver No 26 0.083 98 10 0.102 18
TREX2_ENST00000370231 TREX2 Q9BQ50 Three prime repair exonuclease 2 chrX GO:0000287 Not Cancer Driver No 33 0.14 23 6 0.261 0
TSSK1B TSSK1B Q9BXA7 Testis-specific serine/threonine-protein kinase 1 chr5 GO:0000287 Not Cancer Driver No 104 0.283 114 36 0.316 0
TSSK2 TSSK2 Q96PF2 Testis-specific serine/threonine-protein kinase 2 chr22 GO:0000287 Not Cancer Driver No 50 0.14 91 11 0.121 0
TSSK3 TSSK3 Q96PN8 Testis-specific serine/threonine-protein kinase 3 chr1 GO:0000287 Not Cancer Driver No 30 0.112 0 0 0.0 0
TSSK4_ENST00000287913 TSSK4 Q6SA08 Testis-specific serine/threonine-protein kinase 4 chr14 GO:0000287 Not Cancer Driver No 29 0.088 8 1 0.125 0
TSSK6 TSSK6 Q9BXA6 Testis-specific serine/threonine-protein kinase 6 chr19 GO:0000287 Not Cancer Driver No 47 0.172 0 0 0.0 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 GO:0000287 Not Cancer Driver No 84 0.131 219 33 0.151 0
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 GO:0000287 Not Cancer Driver No 60 0.093 399 27 0.068 0
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:0000287 Not Cancer Driver No 104 0.183 345 65 0.188 1
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0000287 Census, Compendium Yes 164 0.115 373 41 0.11 2
XXYLT1 XXYLT1 Q8NBI6 Xyloside xylosyltransferase 1 chr3 GO:0000287 Not Cancer Driver No 49 0.125 45 6 0.133 0
XYLT2 XYLT2 Q9H1B5 Xylosyltransferase 2 chr17 GO:0000287 Not Cancer Driver No 85 0.098 264 28 0.106 1
YDJC YDJC A8MPS7 Carbohydrate deacetylase chr22 GO:0000287 Not Cancer Driver No 24 0.074 77 4 0.052 0