Total number of protein in "GO:0000228" GO term: 54
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0000228 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
| BAZ1A_ENST00000382422 | BAZ1A | Q9NRL2 | Bromodomain adjacent to zinc finger domain protein 1A | chr14 | GO:0000228 | Census | Yes | 156 | 0.1 | 752 | 65 | 0.086 | 0 |
| BIRC5_ENST00000350051 | BIRC5 | O15392 | Baculoviral IAP repeat-containing protein 5 | chr17 | GO:0000228 | Not Cancer Driver | No | 20 | 0.141 | 49 | 6 | 0.122 | 0 |
| BLM | BLM | P54132 | Bloom syndrome protein | chr15 | GO:0000228 | Census | Yes | 153 | 0.108 | 667 | 70 | 0.105 | 8 |
| CHD1 | CHD1 | O14646 | Chromodomain-helicase-DNA-binding protein 1 | chr5 | GO:0000228 | Not Cancer Driver | No | 172 | 0.101 | 975 | 109 | 0.112 | 4 |
| EXOSC9_ENST00000243498 | EXOSC9 | Q06265 | Exosome complex component RRP45 | chr4 | GO:0000228 | Not Cancer Driver | No | 58 | 0.132 | 154 | 18 | 0.117 | 1 |
| FIGNL1 | FIGNL1 | Q6PIW4 | Fidgetin-like protein 1 | chr7 | GO:0000228 | Not Cancer Driver | No | 75 | 0.111 | 224 | 23 | 0.103 | 0 |
| H2AFY | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:0000228 | Not Cancer Driver | No | 46 | 0.124 | 125 | 19 | 0.152 | 0 |
| H2AFY2 | MACROH2A2 | Q9P0M6 | Core histone macro-H2A.2 | chr10 | GO:0000228 | Not Cancer Driver | No | 59 | 0.159 | 171 | 32 | 0.187 | 0 |
| H2AFZ | H2AZ1 | P0C0S5 | Histone H2A.Z | chr4 | GO:0000228 | Not Cancer Driver | No | 23 | 0.18 | 71 | 16 | 0.225 | 0 |
| H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0000228 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
| H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0000228 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
| HDAC8 | HDAC8 | Q9BY41 | Histone deacetylase 8 | chrX | GO:0000228 | Not Cancer Driver | No | 54 | 0.143 | 32 | 4 | 0.125 | 4 |
| HIST1H3A | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 18 | 0.132 | 51 | 6 | 0.118 | 1 |
| HIST1H3B | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 80 | 0.588 | 51 | 24 | 0.471 | 1 |
| HIST1H3C | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 45 | 0.331 | 51 | 25 | 0.49 | 1 |
| HIST1H3D | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 49 | 0.36 | 51 | 20 | 0.392 | 1 |
| HIST1H3E_ENST00000614911 | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 36 | 0.265 | 51 | 11 | 0.216 | 1 |
| HIST1H3F | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 38 | 0.279 | 51 | 11 | 0.216 | 1 |
| HIST1H3G | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 33 | 0.243 | 51 | 13 | 0.255 | 1 |
| HIST1H3H | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 29 | 0.213 | 51 | 10 | 0.196 | 1 |
| HIST1H3I | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 44 | 0.324 | 51 | 15 | 0.294 | 1 |
| HIST1H3J | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0000228 | Not Cancer Driver | No | 21 | 0.154 | 51 | 10 | 0.196 | 1 |
| HIST1H4A | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 15 | 0.146 | 31 | 5 | 0.161 | 0 |
| HIST1H4B | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 29 | 0.282 | 31 | 6 | 0.194 | 0 |
| HIST1H4C | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 29 | 0.282 | 31 | 7 | 0.226 | 0 |
| HIST1H4D | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 32 | 0.311 | 31 | 8 | 0.258 | 0 |
| HIST1H4E | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 45 | 0.437 | 31 | 14 | 0.452 | 0 |
| HIST1H4F | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 30 | 0.291 | 31 | 7 | 0.226 | 0 |
| HIST1H4H | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 22 | 0.214 | 31 | 9 | 0.29 | 0 |
| HIST1H4I | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 33 | 0.32 | 31 | 10 | 0.323 | 0 |
| HIST1H4J | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 26 | 0.252 | 31 | 9 | 0.29 | 0 |
| HIST1H4K | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 44 | 0.427 | 31 | 13 | 0.419 | 0 |
| HIST1H4L | H4-16 | P62805 | Histone H4 | chr6 | GO:0000228 | Not Cancer Driver | No | 25 | 0.243 | 31 | 14 | 0.452 | 0 |
| HIST4H4 | H4-16 | P62805 | Histone H4 | chr12 | GO:0000228 | Not Cancer Driver | No | 21 | 0.204 | 31 | 7 | 0.226 | 0 |
| HMGA2_ENST00000403681 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:0000228 | Census | Yes | 12 | 0.11 | 109 | 12 | 0.11 | 0 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | GO:0000228 | Not Cancer Driver | No | 77 | 0.093 | 504 | 45 | 0.089 | 0 |
| IK | IK | Q13123 | Protein Red | chr5 | GO:0000228 | Not Cancer Driver | No | 61 | 0.11 | 482 | 50 | 0.104 | 0 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | GO:0000228 | Census | Yes | 35 | 0.106 | 281 | 25 | 0.089 | 0 |
| LRIF1 | LRIF1 | Q5T3J3 | Ligand-dependent nuclear receptor-interacting factor 1 | chr1 | GO:0000228 | Not Cancer Driver | No | 116 | 0.151 | 520 | 74 | 0.142 | 0 |
| NCAPD2 | NCAPD2 | Q15021 | Condensin complex subunit 1 | chr12 | GO:0000228 | Not Cancer Driver | No | 124 | 0.089 | 345 | 35 | 0.101 | 0 |
| PBRM1_ENST00000296302 | PBRM1 | Q86U86 | Protein polybromo-1 | chr3 | GO:0000228 | Census, Compendium | Yes | 209 | 0.124 | 703 | 77 | 0.11 | 0 |
| PINX1 | PINX1 | Q96BK5 | PIN2/TERF1-interacting telomerase inhibitor 1 | chr8 | GO:0000228 | Not Cancer Driver | No | 66 | 0.201 | 328 | 66 | 0.201 | 0 |
| RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0000228 | Not Cancer Driver | No | 42 | 0.124 | 47 | 5 | 0.106 | 3 |
| SETX | SETX | Q7Z333 | Probable helicase senataxin | chr9 | GO:0000228 | Not Cancer Driver | No | 342 | 0.128 | 1240 | 156 | 0.126 | 20 |
| SMARCB1_ENST00000644036 | SMARCB1 | Q12824 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | chr22 | GO:0000228 | Census, Compendium | Yes | 64 | 0.166 | 141 | 35 | 0.248 | 3 |
| SMARCE1 | SMARCE1 | Q969G3 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | chr17 | GO:0000228 | Census | Yes | 47 | 0.114 | 332 | 36 | 0.108 | 2 |
| SMC2 | SMC2 | O95347 | Structural maintenance of chromosomes protein 2 | chr9 | GO:0000228 | Not Cancer Driver | No | 145 | 0.121 | 573 | 88 | 0.154 | 0 |
| SMCHD1 | SMCHD1 | A6NHR9 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | chr18 | GO:0000228 | Not Cancer Driver | No | 240 | 0.12 | 342 | 45 | 0.132 | 45 |
| SPIDR | SPIDR | Q14159 | DNA repair-scaffolding protein | chr8 | GO:0000228 | Not Cancer Driver | No | 101 | 0.11 | 329 | 20 | 0.061 | 0 |
| SPO11 | SPO11 | Q9Y5K1 | Meiotic recombination protein SPO11 | chr20 | GO:0000228 | Not Cancer Driver | No | 59 | 0.149 | 26 | 5 | 0.192 | 0 |
| TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:0000228 | Not Cancer Driver | No | 28 | 0.07 | 310 | 16 | 0.052 | 0 |
| TOP1 | TOP1 | P11387 | DNA topoisomerase 1 | chr20 | GO:0000228 | Census, Compendium | Yes | 93 | 0.122 | 391 | 53 | 0.136 | 0 |
| TOP2A | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | GO:0000228 | Compendium | Yes | 150 | 0.098 | 508 | 59 | 0.116 | 0 |