Total number of protein in "GO:0000082" GO term: 61
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1B_ENST00000257963 | ACVR1B | P36896 | Activin receptor type-1B | chr12 | GO:0000082 | Census | Yes | 114 | 0.226 | 0 | 0 | 0.0 | 0 |
| BCAT1_ENST00000261192 | BCAT1 | P54687 | Branched-chain-amino-acid aminotransferase, cytosolic | chr12 | GO:0000082 | Not Cancer Driver | No | 67 | 0.174 | 8 | 2 | 0.25 | 0 |
| CACUL1 | CACUL1 | Q86Y37 | CDK2-associated and cullin domain-containing protein 1 | chr10 | GO:0000082 | Not Cancer Driver | No | 35 | 0.095 | 128 | 6 | 0.047 | 0 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | GO:0000082 | Not Cancer Driver | No | 83 | 0.174 | 62 | 10 | 0.161 | 7 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0000082 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:0000082 | Census | Yes | 63 | 0.154 | 142 | 26 | 0.183 | 0 |
| CCNE2_ENST00000308108 | CCNE2 | O96020 | G1/S-specific cyclin-E2 | chr8 | GO:0000082 | Not Cancer Driver | No | 46 | 0.114 | 68 | 9 | 0.132 | 0 |
| CDC25A | CDC25A | P30304 | M-phase inducer phosphatase 1 | chr3 | GO:0000082 | Not Cancer Driver | No | 63 | 0.12 | 313 | 35 | 0.112 | 0 |
| CDC34 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | GO:0000082 | Not Cancer Driver | No | 26 | 0.11 | 95 | 11 | 0.116 | 0 |
| CDC7 | CDC7 | O00311 | Cell division cycle 7-related protein kinase | chr1 | GO:0000082 | Not Cancer Driver | No | 72 | 0.125 | 185 | 24 | 0.13 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0000082 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
| CDK3_ENST00000448471 | CDK3 | Q00526 | Cyclin-dependent kinase 3 | chr17 | GO:0000082 | Not Cancer Driver | No | 40 | 0.131 | 17 | 2 | 0.118 | 0 |
| CDK4 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | GO:0000082 | Census, Compendium | Yes | 52 | 0.172 | 52 | 5 | 0.096 | 3 |
| CDK6 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | GO:0000082 | Census | Yes | 40 | 0.123 | 24 | 3 | 0.125 | 1 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0000082 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0000082 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CDKN3 | CDKN3 | Q16667 | Cyclin-dependent kinase inhibitor 3 | chr14 | GO:0000082 | Not Cancer Driver | No | 13 | 0.061 | 33 | 1 | 0.03 | 9 |
| CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | GO:0000082 | Not Cancer Driver | No | 151 | 0.195 | 65 | 9 | 0.138 | 0 |
| CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | GO:0000082 | Not Cancer Driver | No | 87 | 0.117 | 66 | 3 | 0.045 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0000082 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | GO:0000082 | Not Cancer Driver | No | 64 | 0.084 | 102 | 2 | 0.02 | 0 |
| CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | GO:0000082 | Not Cancer Driver | No | 138 | 0.151 | 207 | 38 | 0.184 | 2 |
| CUL5 | CUL5 | Q93034 | Cullin-5 | chr11 | GO:0000082 | Not Cancer Driver | No | 97 | 0.124 | 5 | 1 | 0.2 | 0 |
| DBF4 | DBF4 | Q9UBU7 | Protein DBF4 homolog A | chr7 | GO:0000082 | Not Cancer Driver | No | 75 | 0.111 | 333 | 26 | 0.078 | 0 |
| E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:0000082 | Not Cancer Driver | No | 49 | 0.112 | 272 | 23 | 0.085 | 0 |
| E2F3 | E2F3 | O00716 | Transcription factor E2F3 | chr6 | GO:0000082 | Not Cancer Driver | No | 46 | 0.099 | 253 | 20 | 0.079 | 0 |
| EIF4EBP1 | EIF4EBP1 | Q13541 | Eukaryotic translation initiation factor 4E-binding protein 1 | chr8 | GO:0000082 | Not Cancer Driver | No | 8 | 0.068 | 118 | 8 | 0.068 | 0 |
| EIF4E_ENST00000450253 | EIF4E | P06730 | Eukaryotic translation initiation factor 4E | chr4 | GO:0000082 | Not Cancer Driver | No | 26 | 0.12 | 54 | 6 | 0.111 | 0 |
| GPR132 | GPR132 | Q9UNW8 | Probable G-protein coupled receptor 132 | chr14 | GO:0000082 | Not Cancer Driver | No | 64 | 0.168 | 20 | 3 | 0.15 | 0 |
| GSPT1_ENST00000563468 | GSPT1 | P15170 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A | chr16 | GO:0000082 | Not Cancer Driver | No | 42 | 0.084 | 149 | 13 | 0.087 | 0 |
| HINFP | HINFP | Q9BQA5 | Histone H4 transcription factor | chr11 | GO:0000082 | Not Cancer Driver | No | 65 | 0.126 | 154 | 24 | 0.156 | 0 |
| ID4 | ID4 | P47928 | DNA-binding protein inhibitor ID-4 | chr6 | GO:0000082 | Not Cancer Driver | No | 4 | 0.025 | 71 | 1 | 0.014 | 0 |
| IQGAP3 | IQGAP3 | Q86VI3 | Ras GTPase-activating-like protein IQGAP3 | chr1 | GO:0000082 | Not Cancer Driver | No | 233 | 0.143 | 257 | 36 | 0.14 | 0 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0000082 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
| KHDRBS1 | KHDRBS1 | Q07666 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | chr1 | GO:0000082 | Not Cancer Driver | No | 53 | 0.12 | 362 | 43 | 0.119 | 0 |
| LATS1 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | GO:0000082 | Census, Compendium | Yes | 161 | 0.142 | 788 | 100 | 0.127 | 0 |
| LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | GO:0000082 | Census, Compendium | Yes | 178 | 0.164 | 687 | 116 | 0.169 | 0 |
| MNAT1 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:0000082 | Not Cancer Driver | No | 23 | 0.074 | 64 | 2 | 0.031 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0000082 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| NASP | NASP | P49321 | Nuclear autoantigenic sperm protein | chr1 | GO:0000082 | Not Cancer Driver | No | 95 | 0.121 | 615 | 81 | 0.132 | 0 |
| PHF8 | PHF8 | Q9UPP1 | Histone lysine demethylase PHF8 | chrX | GO:0000082 | Not Cancer Driver | No | 154 | 0.145 | 603 | 93 | 0.154 | 1 |
| PIM2 | PIM2 | Q9P1W9 | Serine/threonine-protein kinase pim-2 | chrX | GO:0000082 | Not Cancer Driver | No | 43 | 0.138 | 47 | 10 | 0.213 | 0 |
| PLK2 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0000082 | Not Cancer Driver | No | 92 | 0.134 | 178 | 21 | 0.118 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0000082 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | GO:0000082 | Census, Compendium | Yes | 409 | 0.179 | 239 | 44 | 0.184 | 3 |
| PPP3CA | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0000082 | Compendium | Yes | 85 | 0.163 | 140 | 27 | 0.193 | 7 |
| PPP6C_ENST00000373547 | PPP6C | O00743 | Serine/threonine-protein phosphatase 6 catalytic subunit | chr9 | GO:0000082 | Census, Compendium | Yes | 63 | 0.207 | 0 | 0 | 0.0 | 0 |
| RBBP8_ENST00000327155 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:0000082 | Not Cancer Driver | No | 99 | 0.11 | 750 | 76 | 0.101 | 1 |
| RCC1_ENST00000373833 | RCC1 | P18754 | Regulator of chromosome condensation | chr1 | GO:0000082 | Not Cancer Driver | No | 54 | 0.128 | 143 | 15 | 0.105 | 0 |
| RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | GO:0000082 | Not Cancer Driver | No | 34 | 0.132 | 63 | 6 | 0.095 | 0 |
| RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | GO:0000082 | Not Cancer Driver | No | 38 | 0.153 | 150 | 25 | 0.167 | 0 |
| RPS6KB1 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0000082 | Not Cancer Driver | No | 45 | 0.086 | 226 | 26 | 0.115 | 0 |
| SKP2 | SKP2 | Q13309 | S-phase kinase-associated protein 2 | chr5 | GO:0000082 | Not Cancer Driver | No | 52 | 0.123 | 52 | 6 | 0.115 | 0 |
| SPDYA_ENST00000379579 | SPDYA | Q5MJ70 | Speedy protein A | chr2 | GO:0000082 | Not Cancer Driver | No | 39 | 0.125 | 119 | 11 | 0.092 | 0 |
| TAF10 | TAF10 | Q12962 | Transcription initiation factor TFIID subunit 10 | chr11 | GO:0000082 | Not Cancer Driver | No | 17 | 0.078 | 131 | 4 | 0.031 | 0 |
| TFDP3 | TFDP3 | Q5H9I0 | Transcription factor Dp family member 3 | chrX | GO:0000082 | Not Cancer Driver | No | 84 | 0.207 | 186 | 42 | 0.226 | 0 |
| TRIM71 | TRIM71 | Q2Q1W2 | E3 ubiquitin-protein ligase TRIM71 | chr3 | GO:0000082 | Not Cancer Driver | No | 124 | 0.143 | 163 | 21 | 0.129 | 2 |
| USP26 | USP26 | Q9BXU7 | Ubiquitin carboxyl-terminal hydrolase 26 | chrX | GO:0000082 | Not Cancer Driver | No | 206 | 0.226 | 325 | 75 | 0.231 | 0 |
| USP29_ENST00000598197 | USP29 | Q9HBJ7 | Ubiquitin carboxyl-terminal hydrolase 29 | chr19 | GO:0000082 | Not Cancer Driver | No | 291 | 0.316 | 432 | 132 | 0.306 | 0 |
| USP37_ENST00000454775 | USP37 | Q86T82 | Ubiquitin carboxyl-terminal hydrolase 37 | chr2 | GO:0000082 | Not Cancer Driver | No | 112 | 0.114 | 530 | 62 | 0.117 | 0 |
| ZNF324 | ZNF324 | O75467 | Zinc finger protein 324A | chr19 | GO:0000082 | Not Cancer Driver | No | 78 | 0.141 | 282 | 38 | 0.135 | 0 |