Total number of protein in "GO:0000079" GO term: 93
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | GO:0000079 | Not Cancer Driver | No | 112 | 0.299 | 43 | 5 | 0.116 | 5 |
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0000079 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0000079 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0000079 | Census, Compendium | Yes | 412 | 0.145 | 2406 | 345 | 0.143 | 22 |
| BCCIP_ENST00000278100 | BCCIP | Q9P287 | BRCA2 and CDKN1A-interacting protein | chr10 | GO:0000079 | Not Cancer Driver | No | 35 | 0.111 | 99 | 16 | 0.162 | 0 |
| BLM | BLM | P54132 | Bloom syndrome protein | chr15 | GO:0000079 | Census | Yes | 153 | 0.108 | 667 | 70 | 0.105 | 8 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0000079 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CCNA1 | CCNA1 | P78396 | Cyclin-A1 | chr13 | GO:0000079 | Not Cancer Driver | No | 112 | 0.241 | 82 | 21 | 0.256 | 0 |
| CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | GO:0000079 | Not Cancer Driver | No | 45 | 0.104 | 186 | 19 | 0.102 | 0 |
| CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | GO:0000079 | Not Cancer Driver | No | 49 | 0.113 | 145 | 14 | 0.097 | 0 |
| CCNB2 | CCNB2 | O95067 | G2/mitotic-specific cyclin-B2 | chr15 | GO:0000079 | Not Cancer Driver | No | 33 | 0.083 | 103 | 10 | 0.097 | 0 |
| CCNB3_ENST00000276014 | CCNB3 | Q8WWL7 | G2/mitotic-specific cyclin-B3 | chrX | GO:0000079 | Not Cancer Driver | No | 270 | 0.194 | 842 | 159 | 0.189 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0000079 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CCND2 | CCND2 | P30279 | G1/S-specific cyclin-D2 | chr12 | GO:0000079 | Census, Compendium | Yes | 39 | 0.135 | 29 | 7 | 0.241 | 5 |
| CCND3 | CCND3 | P30281 | G1/S-specific cyclin-D3 | chr6 | GO:0000079 | Census, Compendium | Yes | 29 | 0.099 | 46 | 8 | 0.174 | 0 |
| CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:0000079 | Census | Yes | 63 | 0.154 | 142 | 26 | 0.183 | 0 |
| CCNE2_ENST00000308108 | CCNE2 | O96020 | G1/S-specific cyclin-E2 | chr8 | GO:0000079 | Not Cancer Driver | No | 46 | 0.114 | 68 | 9 | 0.132 | 0 |
| CCNF | CCNF | P41002 | Cyclin-F | chr16 | GO:0000079 | Not Cancer Driver | No | 106 | 0.135 | 221 | 23 | 0.104 | 3 |
| CCNG1_ENST00000393929 | CCNG1 | P51959 | Cyclin-G1 | chr5 | GO:0000079 | Not Cancer Driver | No | 25 | 0.085 | 0 | 0 | 0.0 | 0 |
| CCNG2_ENST00000395640 | CCNG2 | Q16589 | Cyclin-G2 | chr4 | GO:0000079 | Not Cancer Driver | No | 28 | 0.081 | 14 | 2 | 0.143 | 0 |
| CCNH | CCNH | P51946 | Cyclin-H | chr5 | GO:0000079 | Not Cancer Driver | No | 40 | 0.124 | 28 | 4 | 0.143 | 0 |
| CCNI | CCNI | Q14094 | Cyclin-I | chr4 | GO:0000079 | Not Cancer Driver | No | 30 | 0.08 | 75 | 8 | 0.107 | 0 |
| CCNI2_ENST00000378731 | CCNI2 | Q6ZMN8 | Cyclin-I2 | chr5 | GO:0000079 | Not Cancer Driver | No | 15 | 0.041 | 126 | 0 | 0.0 | 0 |
| CCNJL | CCNJL | Q8IV13 | Cyclin-J-like protein | chr5 | GO:0000079 | Not Cancer Driver | No | 58 | 0.133 | 62 | 7 | 0.113 | 0 |
| CCNJ_ENST00000265992 | CCNJ | Q5T5M9 | Cyclin-J | chr10 | GO:0000079 | Not Cancer Driver | No | 35 | 0.094 | 64 | 4 | 0.062 | 0 |
| CCNK | CCNK | O75909 | Cyclin-K | chr14 | GO:0000079 | Not Cancer Driver | No | 39 | 0.067 | 347 | 15 | 0.043 | 1 |
| CCNL1 | CCNL1 | Q9UK58 | Cyclin-L1 | chr3 | GO:0000079 | Not Cancer Driver | No | 58 | 0.11 | 281 | 38 | 0.135 | 0 |
| CCNO | CCNO | P22674 | Cyclin-O | chr5 | GO:0000079 | Not Cancer Driver | No | 18 | 0.051 | 101 | 3 | 0.03 | 2 |
| CCNT1 | CCNT1 | O60563 | Cyclin-T1 | chr12 | GO:0000079 | Not Cancer Driver | No | 85 | 0.117 | 495 | 61 | 0.123 | 0 |
| CCNT2 | CCNT2 | O60583 | Cyclin-T2 | chr2 | GO:0000079 | Not Cancer Driver | No | 76 | 0.104 | 471 | 52 | 0.11 | 0 |
| CCNY | CCNY | Q8ND76 | Cyclin-Y | chr10 | GO:0000079 | Not Cancer Driver | No | 38 | 0.111 | 94 | 6 | 0.064 | 0 |
| CCNYL1 | CCNYL1 | Q8N7R7 | Cyclin-Y-like protein 1 | chr2 | GO:0000079 | Not Cancer Driver | No | 31 | 0.086 | 100 | 8 | 0.08 | 0 |
| CDC25A | CDC25A | P30304 | M-phase inducer phosphatase 1 | chr3 | GO:0000079 | Not Cancer Driver | No | 63 | 0.12 | 313 | 35 | 0.112 | 0 |
| CDC25C | CDC25C | P30307 | M-phase inducer phosphatase 3 | chr5 | GO:0000079 | Not Cancer Driver | No | 61 | 0.129 | 224 | 26 | 0.116 | 0 |
| CDC37 | CDC37 | Q16543 | Hsp90 co-chaperone Cdc37 | chr19 | GO:0000079 | Not Cancer Driver | No | 52 | 0.138 | 214 | 31 | 0.145 | 0 |
| CDC6 | CDC6 | Q99741 | Cell division control protein 6 homolog | chr17 | GO:0000079 | Not Cancer Driver | No | 57 | 0.102 | 170 | 15 | 0.088 | 1 |
| CDK5R1 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0000079 | Not Cancer Driver | No | 35 | 0.114 | 103 | 16 | 0.155 | 0 |
| CDK5R2 | CDK5R2 | Q13319 | Cyclin-dependent kinase 5 activator 2 | chr2 | GO:0000079 | Not Cancer Driver | No | 14 | 0.038 | 204 | 5 | 0.025 | 0 |
| CDK5RAP1_ENST00000357886 | CDK5RAP1 | Q96SZ6 | Mitochondrial tRNA methylthiotransferase CDK5RAP1 | chr20 | GO:0000079 | Not Cancer Driver | No | 73 | 0.121 | 95 | 12 | 0.126 | 0 |
| CDK5RAP2 | CDK5RAP2 | Q96SN8 | CDK5 regulatory subunit-associated protein 2 | chr9 | GO:0000079 | Not Cancer Driver | No | 217 | 0.115 | 1136 | 128 | 0.113 | 0 |
| CDK5RAP3_ENST00000338399 | CDK5RAP3 | Q96JB5 | CDK5 regulatory subunit-associated protein 3 | chr17 | GO:0000079 | Not Cancer Driver | No | 50 | 0.099 | 99 | 20 | 0.202 | 0 |
| CDK7 | CDK7 | P50613 | Cyclin-dependent kinase 7 | chr5 | GO:0000079 | Not Cancer Driver | No | 41 | 0.118 | 38 | 5 | 0.132 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0000079 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0000079 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CDKN1C | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | GO:0000079 | Not Cancer Driver | No | 2 | 0.006 | 256 | 1 | 0.004 | 7 |
| CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | GO:0000079 | Census, Compendium | Yes | 166 | 1.064 | 83 | 88 | 1.06 | 36 |
| CDKN2B | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | GO:0000079 | Not Cancer Driver | No | 15 | 0.109 | 67 | 3 | 0.045 | 0 |
| CDKN2C_ENST00000371761 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | GO:0000079 | Census, Compendium | Yes | 23 | 0.137 | 49 | 6 | 0.122 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:0000079 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CDKN3 | CDKN3 | Q16667 | Cyclin-dependent kinase inhibitor 3 | chr14 | GO:0000079 | Not Cancer Driver | No | 13 | 0.061 | 33 | 1 | 0.03 | 9 |
| CEBPA | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0000079 | Census, Compendium | Yes | 12 | 0.034 | 342 | 12 | 0.035 | 1 |
| CKS1B | CKS1B | P61024 | Cyclin-dependent kinases regulatory subunit 1 | chr1 | GO:0000079 | Not Cancer Driver | No | 10 | 0.127 | 10 | 0 | 0.0 | 0 |
| CKS2 | CKS2 | P33552 | Cyclin-dependent kinases regulatory subunit 2 | chr9 | GO:0000079 | Not Cancer Driver | No | 9 | 0.114 | 10 | 2 | 0.2 | 0 |
| CNPPD1 | CNPPD1 | Q9BV87 | Protein CNPPD1 | chr2 | GO:0000079 | Not Cancer Driver | No | 49 | 0.12 | 12 | 1 | 0.083 | 0 |
| CNTD2 | CCNP | Q9H8S5 | Cyclin-P | chr19 | GO:0000079 | Not Cancer Driver | No | 25 | 0.081 | 55 | 3 | 0.055 | 0 |
| DIRAS3_ENST00000646789 | DIRAS3 | O95661 | GTP-binding protein Di-Ras3 | chr1 | GO:0000079 | Not Cancer Driver | No | 38 | 0.166 | 21 | 3 | 0.143 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0000079 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | GO:0000079 | Not Cancer Driver | No | 75 | 0.144 | 243 | 38 | 0.156 | 1 |
| GADD45A | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0000079 | Not Cancer Driver | No | 10 | 0.061 | 39 | 5 | 0.128 | 0 |
| GTF2H1_ENST00000453096 | GTF2H1 | P32780 | General transcription factor IIH subunit 1 | chr11 | GO:0000079 | Not Cancer Driver | No | 52 | 0.095 | 139 | 11 | 0.079 | 0 |
| GTPBP4 | GTPBP4 | Q9BZE4 | GTP-binding protein 4 | chr10 | GO:0000079 | Not Cancer Driver | No | 79 | 0.125 | 232 | 34 | 0.147 | 0 |
| HERC5 | HERC5 | Q9UII4 | E3 ISG15--protein ligase HERC5 | chr4 | GO:0000079 | Not Cancer Driver | No | 124 | 0.121 | 118 | 12 | 0.102 | 0 |
| HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | GO:0000079 | Not Cancer Driver | No | 40 | 0.111 | 352 | 40 | 0.114 | 0 |
| HEXIM2_ENST00000592695 | HEXIM2 | Q96MH2 | Protein HEXIM2 | chr17 | GO:0000079 | Not Cancer Driver | No | 35 | 0.122 | 286 | 35 | 0.122 | 0 |
| HHEX | HHEX | Q03014 | Hematopoietically-expressed homeobox protein HHEX | chr10 | GO:0000079 | Not Cancer Driver | No | 23 | 0.085 | 193 | 21 | 0.109 | 0 |
| INCA1_ENST00000576820 | INCA1 | Q0VD86 | Protein INCA1 | chr17 | GO:0000079 | Not Cancer Driver | No | 18 | 0.076 | 195 | 14 | 0.072 | 0 |
| IPO5_ENST00000490680 | IPO5 | O00410 | Importin-5 | chr13 | GO:0000079 | Not Cancer Driver | No | 128 | 0.117 | 52 | 3 | 0.058 | 0 |
| IPO7 | IPO7 | O95373 | Importin-7 | chr11 | GO:0000079 | Not Cancer Driver | No | 138 | 0.133 | 202 | 30 | 0.149 | 0 |
| KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0000079 | Not Cancer Driver | No | 107 | 0.129 | 266 | 27 | 0.102 | 0 |
| LATS1 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | GO:0000079 | Census, Compendium | Yes | 161 | 0.142 | 788 | 100 | 0.127 | 0 |
| LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | GO:0000079 | Census, Compendium | Yes | 178 | 0.164 | 687 | 116 | 0.169 | 0 |
| MAPRE3 | MAPRE3 | Q9UPY8 | Microtubule-associated protein RP/EB family member 3 | chr2 | GO:0000079 | Not Cancer Driver | No | 37 | 0.132 | 120 | 16 | 0.133 | 0 |
| MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0000079 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
| MNAT1 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:0000079 | Not Cancer Driver | No | 23 | 0.074 | 64 | 2 | 0.031 | 0 |
| MYOCD_ENST00000343344 | MYOCD | Q8IZQ8 | Myocardin | chr17 | GO:0000079 | Not Cancer Driver | No | 284 | 0.303 | 853 | 263 | 0.308 | 0 |
| NR2F2 | NR2F2 | P24468 | COUP transcription factor 2 | chr15 | GO:0000079 | Not Cancer Driver | No | 66 | 0.159 | 101 | 1 | 0.01 | 5 |
| PDGFB | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0000079 | Census | Yes | 37 | 0.154 | 99 | 22 | 0.222 | 2 |
| PKD1 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0000079 | Not Cancer Driver | No | 393 | 0.091 | 690 | 66 | 0.096 | 92 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0000079 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| PKMYT1 | PKMYT1 | Q99640 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | chr16 | GO:0000079 | Not Cancer Driver | No | 39 | 0.078 | 228 | 19 | 0.083 | 0 |
| PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | GO:0000079 | Not Cancer Driver | No | 87 | 0.144 | 119 | 13 | 0.109 | 0 |
| PROX1 | PROX1 | Q92786 | Prospero homeobox protein 1 | chr1 | GO:0000079 | Not Cancer Driver | No | 182 | 0.247 | 537 | 141 | 0.263 | 0 |
| PSMD10 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | GO:0000079 | Not Cancer Driver | No | 20 | 0.088 | 53 | 5 | 0.094 | 0 |
| PSRC1_ENST00000409138 | PSRC1 | Q6PGN9 | Proline/serine-rich coiled-coil protein 1 | chr1 | GO:0000079 | Not Cancer Driver | No | 30 | 0.083 | 361 | 30 | 0.083 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0000079 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| RGCC | RGCC | Q9H4X1 | Regulator of cell cycle RGCC | chr13 | GO:0000079 | Not Cancer Driver | No | 9 | 0.066 | 81 | 7 | 0.086 | 0 |
| SERTAD1 | SERTAD1 | Q9UHV2 | SERTA domain-containing protein 1 | chr19 | GO:0000079 | Not Cancer Driver | No | 24 | 0.102 | 164 | 18 | 0.11 | 0 |
| SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0000079 | Not Cancer Driver | No | 27 | 0.109 | 75 | 9 | 0.12 | 0 |
| SPDYA_ENST00000379579 | SPDYA | Q5MJ70 | Speedy protein A | chr2 | GO:0000079 | Not Cancer Driver | No | 39 | 0.125 | 119 | 11 | 0.092 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0000079 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| TFAP4 | TFAP4 | Q01664 | Transcription factor AP-4 | chr16 | GO:0000079 | Compendium | Yes | 61 | 0.18 | 285 | 52 | 0.182 | 0 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0000079 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| WEE2 | WEE2 | P0C1S8 | Wee1-like protein kinase 2 | chr7 | GO:0000079 | Not Cancer Driver | No | 104 | 0.183 | 345 | 65 | 0.188 | 1 |