Total number of protein in "GO:0000049" GO term: 71
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AARS | AARS1 | P49588 | Alanine--tRNA ligase, cytoplasmic | chr16 | GO:0000049 | Not Cancer Driver | No | 97 | 0.1 | 140 | 14 | 0.1 | 5 |
| AARS2 | AARS2 | Q5JTZ9 | Alanine--tRNA ligase, mitochondrial | chr6 | GO:0000049 | Not Cancer Driver | No | 123 | 0.125 | 203 | 25 | 0.123 | 5 |
| AIMP1_ENST00000442366 | AIMP1 | Q12904 | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 | chr4 | GO:0000049 | Not Cancer Driver | No | 31 | 0.099 | 161 | 19 | 0.118 | 0 |
| ALKBH1 | ALKBH1 | Q13686 | Nucleic acid dioxygenase ALKBH1 | chr14 | GO:0000049 | Not Cancer Driver | No | 55 | 0.141 | 77 | 11 | 0.143 | 0 |
| ALKBH8_ENST00000389568 | ALKBH8 | Q96BT7 | Alkylated DNA repair protein alkB homolog 8 | chr11 | GO:0000049 | Not Cancer Driver | No | 50 | 0.075 | 189 | 12 | 0.063 | 0 |
| C6orf203_ENST00000405204 | MTRES1 | Q9P0P8 | Mitochondrial transcription rescue factor 1 | chr6 | GO:0000049 | Not Cancer Driver | No | 28 | 0.117 | 45 | 4 | 0.089 | 0 |
| CARS_ENST00000397111 | CARS1 | P49589 | Cysteine--tRNA ligase, cytoplasmic | chr11 | GO:0000049 | Not Cancer Driver | No | 97 | 0.13 | 184 | 35 | 0.19 | 3 |
| CTU1 | CTU1 | Q7Z7A3 | Cytoplasmic tRNA 2-thiolation protein 1 | chr19 | GO:0000049 | Not Cancer Driver | No | 12 | 0.034 | 60 | 1 | 0.017 | 0 |
| CTU2_ENST00000453996 | CTU2 | Q2VPK5 | Cytoplasmic tRNA 2-thiolation protein 2 | chr16 | GO:0000049 | Not Cancer Driver | No | 46 | 0.089 | 137 | 11 | 0.08 | 0 |
| DALRD3 | DALRD3 | Q5D0E6 | DALR anticodon-binding domain-containing protein 3 | chr3 | GO:0000049 | Not Cancer Driver | No | 49 | 0.09 | 40 | 4 | 0.1 | 0 |
| DARS2 | DARS2 | Q6PI48 | Aspartate--tRNA ligase, mitochondrial | chr1 | GO:0000049 | Not Cancer Driver | No | 63 | 0.098 | 91 | 11 | 0.121 | 11 |
| DTD1 | DTD1 | Q8TEA8 | D-aminoacyl-tRNA deacylase 1 | chr20 | GO:0000049 | Not Cancer Driver | No | 45 | 0.215 | 93 | 26 | 0.28 | 0 |
| DTD2_ENST00000356180 | DTD2 | Q96FN9 | D-aminoacyl-tRNA deacylase 2 | chr14 | GO:0000049 | Not Cancer Driver | No | 12 | 0.071 | 11 | 1 | 0.091 | 0 |
| DUS2 | DUS2 | Q9NX74 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | chr16 | GO:0000049 | Not Cancer Driver | No | 48 | 0.097 | 117 | 10 | 0.085 | 0 |
| EARS2_ENST00000449606 | EARS2 | Q5JPH6 | Probable glutamate--tRNA ligase, mitochondrial | chr16 | GO:0000049 | Not Cancer Driver | No | 56 | 0.107 | 99 | 14 | 0.141 | 14 |
| EEF1A1 | EEF1A1 | P68104 | Elongation factor 1-alpha 1 | chr6 | GO:0000049 | Not Cancer Driver | No | 109 | 0.236 | 100 | 14 | 0.14 | 0 |
| EEFSEC | EEFSEC | P57772 | Selenocysteine-specific elongation factor | chr3 | GO:0000049 | Not Cancer Driver | No | 80 | 0.134 | 124 | 21 | 0.169 | 0 |
| EIF2A | EIF2A | Q9BY44 | Eukaryotic translation initiation factor 2A | chr3 | GO:0000049 | Not Cancer Driver | No | 51 | 0.087 | 162 | 19 | 0.117 | 0 |
| EIF2AK4 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | GO:0000049 | Not Cancer Driver | No | 156 | 0.095 | 494 | 44 | 0.089 | 2 |
| EIF2S3 | EIF2S3 | P41091 | Eukaryotic translation initiation factor 2 subunit 3 | chrX | GO:0000049 | Not Cancer Driver | No | 52 | 0.11 | 51 | 7 | 0.137 | 1 |
| EIF2S3B | EIF2S3B | Q2VIR3 | Eukaryotic translation initiation factor 2 subunit 3B | chr12 | GO:0000049 | Not Cancer Driver | No | 16 | 0.034 | 53 | 2 | 0.038 | 0 |
| ELP1 | ELP1 | O95163 | Elongator complex protein 1 | chr9 | GO:0000049 | Not Cancer Driver | No | 143 | 0.107 | 157 | 23 | 0.146 | 2 |
| ELP3 | ELP3 | Q9H9T3 | Elongator complex protein 3 | chr8 | GO:0000049 | Not Cancer Driver | No | 60 | 0.11 | 19 | 4 | 0.211 | 0 |
| ELP5_ENST00000354429 | ELP5 | Q8TE02 | Elongator complex protein 5 | chr17 | GO:0000049 | Not Cancer Driver | No | 33 | 0.104 | 131 | 14 | 0.107 | 0 |
| FARS2_ENST00000274680 | FARS2 | O95363 | Phenylalanine--tRNA ligase, mitochondrial | chr6 | GO:0000049 | Not Cancer Driver | No | 66 | 0.146 | 73 | 17 | 0.233 | 4 |
| FARSA | FARSA | Q9Y285 | Phenylalanine--tRNA ligase alpha subunit | chr19 | GO:0000049 | Not Cancer Driver | No | 75 | 0.148 | 120 | 25 | 0.208 | 0 |
| HSD17B10 | HSD17B10 | Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | chrX | GO:0000049 | Not Cancer Driver | No | 27 | 0.103 | 15 | 3 | 0.2 | 11 |
| IARS | IARS1 | P41252 | Isoleucine--tRNA ligase, cytoplasmic | chr9 | GO:0000049 | Not Cancer Driver | No | 130 | 0.103 | 28 | 4 | 0.143 | 4 |
| IARS2 | IARS2 | Q9NSE4 | Isoleucine--tRNA ligase, mitochondrial | chr1 | GO:0000049 | Not Cancer Driver | No | 149 | 0.147 | 145 | 22 | 0.152 | 0 |
| IFIT5 | IFIT5 | Q13325 | Interferon-induced protein with tetratricopeptide repeats 5 | chr10 | GO:0000049 | Not Cancer Driver | No | 43 | 0.089 | 19 | 0 | 0.0 | 0 |
| IGHMBP2 | IGHMBP2 | P38935 | DNA-binding protein SMUBP-2 | chr11 | GO:0000049 | Not Cancer Driver | No | 136 | 0.137 | 354 | 53 | 0.15 | 31 |
| KARS_ENST00000302445 | KARS1 | Q15046 | Lysine--tRNA ligase | chr16 | GO:0000049 | Not Cancer Driver | No | 88 | 0.147 | 160 | 15 | 0.094 | 12 |
| MARS | MARS1 | P56192 | Methionine--tRNA ligase, cytoplasmic | chr12 | GO:0000049 | Not Cancer Driver | No | 91 | 0.101 | 151 | 16 | 0.106 | 8 |
| METTL1 | METTL1 | Q9UBP6 | tRNA (guanine-N(7)-)-methyltransferase | chr12 | GO:0000049 | Not Cancer Driver | No | 43 | 0.156 | 89 | 11 | 0.124 | 0 |
| MRPS27_ENST00000261413 | MRPS27 | Q92552 | 28S ribosomal protein S27, mitochondrial | chr5 | GO:0000049 | Not Cancer Driver | No | 46 | 0.111 | 51 | 7 | 0.137 | 0 |
| NAT10 | NAT10 | Q9H0A0 | RNA cytidine acetyltransferase | chr11 | GO:0000049 | Not Cancer Driver | No | 109 | 0.106 | 142 | 18 | 0.127 | 0 |
| NEMF | NEMF | O60524 | Ribosome quality control complex subunit NEMF | chr14 | GO:0000049 | Not Cancer Driver | No | 109 | 0.101 | 517 | 61 | 0.118 | 0 |
| NSUN2 | NSUN2 | Q08J23 | RNA cytosine C(5)-methyltransferase NSUN2 | chr5 | GO:0000049 | Not Cancer Driver | No | 112 | 0.146 | 221 | 21 | 0.095 | 1 |
| NSUN3 | NSUN3 | Q9H649 | tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial | chr3 | GO:0000049 | Not Cancer Driver | No | 34 | 0.1 | 0 | 0 | 0.0 | 0 |
| NSUN6 | NSUN6 | Q8TEA1 | tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 | chr10 | GO:0000049 | Not Cancer Driver | No | 68 | 0.145 | 50 | 10 | 0.2 | 0 |
| PSTK | PSTK | Q8IV42 | L-seryl-tRNA(Sec) kinase | chr10 | GO:0000049 | Not Cancer Driver | No | 48 | 0.138 | 79 | 15 | 0.19 | 0 |
| PTCD1 | PTCD1 | O75127 | Pentatricopeptide repeat-containing protein 1, mitochondrial | chr7 | GO:0000049 | Not Cancer Driver | No | 99 | 0.141 | 224 | 42 | 0.188 | 0 |
| PUS1 | PUS1 | Q9Y606 | Pseudouridylate synthase 1 homolog | chr12 | GO:0000049 | Not Cancer Driver | No | 48 | 0.112 | 157 | 18 | 0.115 | 1 |
| RARS | RARS1 | P54136 | Arginine--tRNA ligase, cytoplasmic | chr5 | GO:0000049 | Not Cancer Driver | No | 72 | 0.109 | 41 | 3 | 0.073 | 2 |
| RPL35A | RPL35A | P18077 | 60S ribosomal protein L35a | chr3 | GO:0000049 | Not Cancer Driver | No | 9 | 0.082 | 25 | 0 | 0.0 | 1 |
| RPUSD4 | RPUSD4 | Q96CM3 | Pseudouridylate synthase RPUSD4, mitochondrial | chr11 | GO:0000049 | Not Cancer Driver | No | 54 | 0.143 | 97 | 15 | 0.155 | 0 |
| SARS2_ENST00000221431 | SARS2 | Q9NP81 | Serine--tRNA ligase, mitochondrial | chr19 | GO:0000049 | Not Cancer Driver | No | 64 | 0.124 | 111 | 14 | 0.126 | 1 |
| SARS_ENST00000234677 | SARS1 | P49591 | Serine--tRNA ligase, cytoplasmic | chr1 | GO:0000049 | Not Cancer Driver | No | 56 | 0.109 | 83 | 4 | 0.048 | 1 |
| SEPSECS | SEPSECS | Q9HD40 | O-phosphoseryl-tRNA(Sec) selenium transferase | chr4 | GO:0000049 | Not Cancer Driver | No | 47 | 0.094 | 22 | 7 | 0.318 | 3 |
| SLFN11_ENST00000308377 | SLFN11 | Q7Z7L1 | Schlafen family member 11 | chr17 | GO:0000049 | Not Cancer Driver | No | 177 | 0.196 | 34 | 8 | 0.235 | 0 |
| SLFN13 | SLFN13 | Q68D06 | Schlafen family member 13 | chr17 | GO:0000049 | Not Cancer Driver | No | 152 | 0.169 | 45 | 5 | 0.111 | 0 |
| SSB | SSB | P05455 | Lupus La protein | chr2 | GO:0000049 | Not Cancer Driver | No | 39 | 0.096 | 181 | 18 | 0.099 | 0 |
| TARS_ENST00000265112 | TARS1 | P26639 | Threonine--tRNA ligase 1, cytoplasmic | chr5 | GO:0000049 | Not Cancer Driver | No | 112 | 0.155 | 112 | 22 | 0.196 | 2 |
| TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:0000049 | Census | Yes | 110 | 0.097 | 212 | 16 | 0.075 | 31 |
| THG1L | THG1L | Q9NWX6 | Probable tRNA(His) guanylyltransferase | chr5 | GO:0000049 | Not Cancer Driver | No | 32 | 0.107 | 22 | 2 | 0.091 | 1 |
| TRMT10A_ENST00000394876 | TRMT10A | Q8TBZ6 | tRNA methyltransferase 10 homolog A | chr4 | GO:0000049 | Not Cancer Driver | No | 49 | 0.145 | 182 | 28 | 0.154 | 1 |
| TRMT10B | TRMT10B | Q6PF06 | tRNA methyltransferase 10 homolog B | chr9 | GO:0000049 | Not Cancer Driver | No | 35 | 0.111 | 75 | 13 | 0.173 | 0 |
| TRMT10C | TRMT10C | Q7L0Y3 | tRNA methyltransferase 10 homolog C | chr3 | GO:0000049 | Not Cancer Driver | No | 56 | 0.139 | 59 | 10 | 0.169 | 2 |
| TRMT11 | TRMT11 | Q7Z4G4 | tRNA (guanine(10)-N2)-methyltransferase homolog | chr6 | GO:0000049 | Not Cancer Driver | No | 38 | 0.082 | 45 | 3 | 0.067 | 0 |
| TRMT1L | TRMT1L | Q7Z2T5 | TRMT1-like protein | chr1 | GO:0000049 | Not Cancer Driver | No | 71 | 0.097 | 241 | 19 | 0.079 | 0 |
| TRMT1_ENST00000357720 | TRMT1 | Q9NXH9 | tRNA (guanine(26)-N(2))-dimethyltransferase | chr19 | GO:0000049 | Not Cancer Driver | No | 82 | 0.124 | 200 | 24 | 0.12 | 0 |
| TRMT9B | TRMT9B | Q9P272 | Probable tRNA methyltransferase 9B | chr8 | GO:0000049 | Not Cancer Driver | No | 73 | 0.161 | 151 | 16 | 0.106 | 0 |
| TRMU | TRMU | O75648 | Mitochondrial tRNA-specific 2-thiouridylase 1 | chr22 | GO:0000049 | Not Cancer Driver | No | 40 | 0.095 | 28 | 5 | 0.179 | 2 |
| TRNAU1AP | TRNAU1AP | Q9NX07 | tRNA selenocysteine 1-associated protein 1 | chr1 | GO:0000049 | Not Cancer Driver | No | 28 | 0.098 | 32 | 4 | 0.125 | 0 |
| TRNT1 | TRNT1 | Q96Q11 | CCA tRNA nucleotidyltransferase 1, mitochondrial | chr3 | GO:0000049 | Not Cancer Driver | No | 60 | 0.138 | 49 | 8 | 0.163 | 7 |
| TYW5 | TYW5 | A2RUC4 | tRNA wybutosine-synthesizing protein 5 | chr2 | GO:0000049 | Not Cancer Driver | No | 32 | 0.102 | 11 | 1 | 0.091 | 0 |
| XPO5 | XPO5 | Q9HAV4 | Exportin-5 | chr6 | GO:0000049 | Not Cancer Driver | No | 112 | 0.093 | 64 | 7 | 0.109 | 0 |
| XPOT | XPOT | O43592 | Exportin-T | chr12 | GO:0000049 | Not Cancer Driver | No | 114 | 0.119 | 0 | 0 | 0.0 | 0 |
| YARS | YARS1 | P54577 | Tyrosine--tRNA ligase, cytoplasmic | chr1 | GO:0000049 | Not Cancer Driver | No | 62 | 0.117 | 109 | 9 | 0.083 | 3 |
| YARS2 | YARS2 | Q9Y2Z4 | Tyrosine--tRNA ligase, mitochondrial | chr12 | GO:0000049 | Not Cancer Driver | No | 59 | 0.124 | 62 | 11 | 0.177 | 2 |
| YRDC | YRDC | Q86U90 | Threonylcarbamoyl-AMP synthase | chr1 | GO:0000049 | Not Cancer Driver | No | 17 | 0.061 | 45 | 1 | 0.022 | 2 |