Total number of protein in "GO:0000045" GO term: 59
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMBRA1_ENST00000458649 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:0000045 | Not Cancer Driver | No | 173 | 0.133 | 788 | 103 | 0.131 | 0 |
| AP4M1_ENST00000421755 | AP4M1 | O00189 | AP-4 complex subunit mu-1 | chr7 | GO:0000045 | Not Cancer Driver | No | 63 | 0.139 | 64 | 7 | 0.109 | 0 |
| ATG101 | ATG101 | Q9BSB4 | Autophagy-related protein 101 | chr12 | GO:0000045 | Not Cancer Driver | No | 21 | 0.096 | 5 | 0 | 0.0 | 0 |
| ATG12 | ATG12 | O94817 | Ubiquitin-like protein ATG12 | chr5 | GO:0000045 | Not Cancer Driver | No | 15 | 0.107 | 60 | 8 | 0.133 | 0 |
| ATG13_ENST00000359513 | ATG13 | O75143 | Autophagy-related protein 13 | chr11 | GO:0000045 | Not Cancer Driver | No | 55 | 0.106 | 205 | 27 | 0.132 | 0 |
| ATG14 | ATG14 | Q6ZNE5 | Beclin 1-associated autophagy-related key regulator | chr14 | GO:0000045 | Not Cancer Driver | No | 48 | 0.098 | 209 | 24 | 0.115 | 0 |
| ATG16L1 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | GO:0000045 | Not Cancer Driver | No | 79 | 0.13 | 239 | 25 | 0.105 | 1 |
| ATG16L2 | ATG16L2 | Q8NAA4 | Protein Atg16l2 | chr11 | GO:0000045 | Not Cancer Driver | No | 43 | 0.069 | 171 | 7 | 0.041 | 0 |
| ATG2A | ATG2A | Q2TAZ0 | Autophagy-related protein 2 homolog A | chr11 | GO:0000045 | Not Cancer Driver | No | 228 | 0.118 | 887 | 124 | 0.14 | 0 |
| ATG2B | ATG2B | Q96BY7 | Autophagy-related protein 2 homolog B | chr14 | GO:0000045 | Not Cancer Driver | No | 264 | 0.127 | 679 | 111 | 0.163 | 0 |
| ATG3 | ATG3 | Q9NT62 | Ubiquitin-like-conjugating enzyme ATG3 | chr3 | GO:0000045 | Not Cancer Driver | No | 29 | 0.092 | 110 | 9 | 0.082 | 0 |
| ATG5_ENST00000343245 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | GO:0000045 | Not Cancer Driver | No | 40 | 0.145 | 25 | 6 | 0.24 | 1 |
| ATG7 | ATG7 | O95352 | Ubiquitin-like modifier-activating enzyme ATG7 | chr3 | GO:0000045 | Compendium | Yes | 77 | 0.11 | 53 | 8 | 0.151 | 6 |
| ATG9A | ATG9A | Q7Z3C6 | Autophagy-related protein 9A | chr2 | GO:0000045 | Not Cancer Driver | No | 92 | 0.11 | 252 | 30 | 0.119 | 0 |
| ATG9B | ATG9B | Q674R7 | Autophagy-related protein 9B | chr7 | GO:0000045 | Not Cancer Driver | No | 92 | 0.1 | 368 | 43 | 0.117 | 0 |
| ATP2A2 | ATP2A2 | P16615 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | chr12 | GO:0000045 | Not Cancer Driver | No | 136 | 0.131 | 78 | 14 | 0.179 | 41 |
| BAG3 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | GO:0000045 | Not Cancer Driver | No | 57 | 0.099 | 571 | 57 | 0.1 | 7 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0000045 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| EMC6 | EMC6 | Q9BV81 | ER membrane protein complex subunit 6 | chr17 | GO:0000045 | Not Cancer Driver | No | 4 | 0.036 | 0 | 0 | 0.0 | 0 |
| GABARAP | GABARAP | O95166 | Gamma-aminobutyric acid receptor-associated protein | chr17 | GO:0000045 | Not Cancer Driver | No | 9 | 0.077 | 11 | 0 | 0.0 | 0 |
| GABARAPL1_ENST00000545887 | GABARAPL1 | Q9H0R8 | Gamma-aminobutyric acid receptor-associated protein-like 1 | chr12 | GO:0000045 | Not Cancer Driver | No | 19 | 0.162 | 10 | 1 | 0.1 | 0 |
| GABARAPL2 | GABARAPL2 | P60520 | Gamma-aminobutyric acid receptor-associated protein-like 2 | chr16 | GO:0000045 | Not Cancer Driver | No | 11 | 0.094 | 2 | 1 | 0.5 | 0 |
| IRGM | IRGM | A1A4Y4 | Immunity-related GTPase family M protein | chr5 | GO:0000045 | Not Cancer Driver | No | 9 | 0.05 | 45 | 1 | 0.022 | 0 |
| KIAA1324 | ELAPOR1 | Q6UXG2 | Endosome/lysosome-associated apoptosis and autophagy regulator 1 | chr1 | GO:0000045 | Not Cancer Driver | No | 94 | 0.093 | 56 | 5 | 0.089 | 0 |
| MAP1LC3A_ENST00000397709 | MAP1LC3A | Q9H492 | Microtubule-associated proteins 1A/1B light chain 3A | chr20 | GO:0000045 | Not Cancer Driver | No | 22 | 0.182 | 24 | 1 | 0.042 | 0 |
| MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | GO:0000045 | Not Cancer Driver | No | 10 | 0.08 | 17 | 1 | 0.059 | 0 |
| MAP1LC3B2 | MAP1LC3B2 | A6NCE7 | Microtubule-associated proteins 1A/1B light chain 3 beta 2 | chr12 | GO:0000045 | Not Cancer Driver | No | 19 | 0.152 | 17 | 7 | 0.412 | 0 |
| MAP1LC3C | MAP1LC3C | Q9BXW4 | Microtubule-associated proteins 1A/1B light chain 3C | chr1 | GO:0000045 | Not Cancer Driver | No | 32 | 0.218 | 31 | 5 | 0.161 | 0 |
| NSFL1C_ENST00000216879 | NSFL1C | Q9UNZ2 | NSFL1 cofactor p47 | chr20 | GO:0000045 | Not Cancer Driver | No | 56 | 0.151 | 266 | 39 | 0.147 | 0 |
| PACS2_ENST00000325438 | PACS2 | Q86VP3 | Phosphofurin acidic cluster sorting protein 2 | chr14 | GO:0000045 | Not Cancer Driver | No | 122 | 0.137 | 460 | 59 | 0.128 | 1 |
| PIK3C3 | PIK3C3 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | chr18 | GO:0000045 | Not Cancer Driver | No | 127 | 0.143 | 191 | 34 | 0.178 | 0 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0000045 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
| RAB19_ENST00000356407 | RAB19 | A4D1S5 | Ras-related protein Rab-19 | chr7 | GO:0000045 | Not Cancer Driver | No | 39 | 0.18 | 2 | 0 | 0.0 | 0 |
| RAB1A | RAB1A | P62820 | Ras-related protein Rab-1A | chr2 | GO:0000045 | Not Cancer Driver | No | 16 | 0.078 | 38 | 2 | 0.053 | 0 |
| RAB1B | RAB1B | Q9H0U4 | Ras-related protein Rab-1B | chr11 | GO:0000045 | Not Cancer Driver | No | 24 | 0.119 | 40 | 3 | 0.075 | 0 |
| RAB23_ENST00000317483 | RAB23 | Q9ULC3 | Ras-related protein Rab-23 | chr6 | GO:0000045 | Not Cancer Driver | No | 28 | 0.118 | 62 | 6 | 0.097 | 2 |
| RAB33B | RAB33B | Q9H082 | Ras-related protein Rab-33B | chr4 | GO:0000045 | Not Cancer Driver | No | 22 | 0.096 | 30 | 3 | 0.1 | 2 |
| RAB43_ENST00000393305 | RAB43 | Q86YS6 | Ras-related protein Rab-43 | chr3 | GO:0000045 | Not Cancer Driver | No | 26 | 0.123 | 14 | 0 | 0.0 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | GO:0000045 | Not Cancer Driver | No | 27 | 0.13 | 11 | 0 | 0.0 | 4 |
| RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | GO:0000045 | Not Cancer Driver | No | 202 | 0.127 | 578 | 75 | 0.13 | 0 |
| RUFY4_ENST00000344321 | RUFY4 | Q6ZNE9 | RUN and FYVE domain-containing protein 4 | chr2 | GO:0000045 | Not Cancer Driver | No | 77 | 0.135 | 307 | 51 | 0.166 | 0 |
| STX12 | STX12 | Q86Y82 | Syntaxin-12 | chr1 | GO:0000045 | Not Cancer Driver | No | 21 | 0.076 | 156 | 9 | 0.058 | 0 |
| SYNPO2_ENST00000429713 | SYNPO2 | Q9UMS6 | Synaptopodin-2 | chr4 | GO:0000045 | Not Cancer Driver | No | 240 | 0.22 | 978 | 219 | 0.224 | 0 |
| TCIRG1 | TCIRG1 | Q13488 | V-type proton ATPase 116 kDa subunit a 3 | chr11 | GO:0000045 | Compendium | Yes | 68 | 0.082 | 102 | 6 | 0.059 | 5 |
| TMEM173 | STING1 | Q86WV6 | Stimulator of interferon genes protein | chr5 | GO:0000045 | Not Cancer Driver | No | 46 | 0.121 | 66 | 13 | 0.197 | 3 |
| TMEM41B_ENST00000611268 | TMEM41B | Q5BJD5 | Transmembrane protein 41B | chr11 | GO:0000045 | Not Cancer Driver | No | 19 | 0.065 | 47 | 3 | 0.064 | 0 |
| TP53INP1 | TP53INP1 | Q96A56 | Tumor protein p53-inducible nuclear protein 1 | chr8 | GO:0000045 | Not Cancer Driver | No | 32 | 0.133 | 134 | 20 | 0.149 | 0 |
| TP53INP2 | TP53INP2 | Q8IXH6 | Tumor protein p53-inducible nuclear protein 2 | chr20 | GO:0000045 | Not Cancer Driver | No | 18 | 0.082 | 197 | 16 | 0.081 | 0 |
| UBQLN1 | UBQLN1 | Q9UMX0 | Ubiquilin-1 | chr9 | GO:0000045 | Not Cancer Driver | No | 64 | 0.109 | 543 | 58 | 0.107 | 0 |
| UBQLN2 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | GO:0000045 | Not Cancer Driver | No | 82 | 0.131 | 581 | 79 | 0.136 | 8 |
| UBXN2A | UBXN2A | P68543 | UBX domain-containing protein 2A | chr2 | GO:0000045 | Not Cancer Driver | No | 37 | 0.143 | 58 | 11 | 0.19 | 0 |
| UBXN2B | UBXN2B | Q14CS0 | UBX domain-containing protein 2B | chr8 | GO:0000045 | Not Cancer Driver | No | 51 | 0.154 | 162 | 16 | 0.099 | 0 |
| ULK1 | ULK1 | O75385 | Serine/threonine-protein kinase ULK1 | chr12 | GO:0000045 | Not Cancer Driver | No | 142 | 0.135 | 588 | 77 | 0.131 | 0 |
| ULK2_ENST00000361658 | ULK2 | Q8IYT8 | Serine/threonine-protein kinase ULK2 | chr17 | GO:0000045 | Not Cancer Driver | No | 132 | 0.127 | 519 | 84 | 0.162 | 0 |
| VMP1 | VMP1 | Q96GC9 | Vacuole membrane protein 1 | chr17 | GO:0000045 | Not Cancer Driver | No | 57 | 0.14 | 68 | 11 | 0.162 | 0 |
| WDR45B | WDR45B | Q5MNZ6 | WD repeat domain phosphoinositide-interacting protein 3 | chr17 | GO:0000045 | Not Cancer Driver | No | 48 | 0.14 | 8 | 1 | 0.125 | 0 |
| WDR45_ENST00000634944 | WDR45 | Q9Y484 | WD repeat domain phosphoinositide-interacting protein 4 | chrX | GO:0000045 | Compendium | Yes | 62 | 0.172 | 10 | 1 | 0.1 | 0 |
| WIPI1 | WIPI1 | Q5MNZ9 | WD repeat domain phosphoinositide-interacting protein 1 | chr17 | GO:0000045 | Not Cancer Driver | No | 45 | 0.101 | 113 | 9 | 0.08 | 0 |
| WIPI2 | WIPI2 | Q9Y4P8 | WD repeat domain phosphoinositide-interacting protein 2 | chr7 | GO:0000045 | Not Cancer Driver | No | 64 | 0.141 | 68 | 5 | 0.074 | 1 |