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FAAP20_ENST00000378546 ,FAAP20 ,Q6NZ36
  • Uniprot Accession= Q6NZ36
  • Ensembl Transcript= ENST00000378546.8
  • Uniprot Name= FAAP20
  • Name= Fanconi anemia core complex-associated protein 20
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 17
GO term GO name GO namespace GO def
GO:0000785 chromatin cellular_component The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. [GOC:elh, PMID:20404130]
GO:0005488 binding molecular_function The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732]
GO:0043130 ubiquitin binding molecular_function Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. [GOC:ecd]
GO:0019985 translesion synthesis biological_process The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. [GOC:elh, GOC:vw, PMID:10535901]
GO:0043240 Fanconi anaemia nuclear complex cellular_component A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage. [GOC:jl, PMID:12093742]
GO:0006513 protein monoubiquitination biological_process Addition of a single ubiquitin group to a protein. [GOC:ai]
GO:0006974 cellular response to DNA damage stimulus biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. [GOC:go_curators]
GO:0046872 metal ion binding molecular_function Binding to a metal ion. [GOC:ai]
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding molecular_function Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein. [GOC:mah, PMID:15556404, PMID:17525341]
GO:0030054 cell junction cellular_component A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. [GOC:aruk, GOC:bc, GOC:mah, http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html, ISBN:0198506732, PMID:26820516, PMID:28096264]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0036297 interstrand cross-link repair biological_process Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. [GOC:vw, PMID:16464006, PMID:22064477]
GO:0031593 polyubiquitin modification-dependent protein binding molecular_function Binding to a protein upon poly-ubiquitination of the target protein. [GOC:pg]
GO:0140030 modification-dependent protein binding molecular_function Binding to a protein upon post-translation modification of the target protein. [PMID:26060076]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0016604 nuclear body cellular_component Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. [GOC:ma, PMID:10330182]
GO:0005694 chromosome cellular_component A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. [ISBN:0198547684]