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EXOC8 ,EXOC8 ,Q8IYI6
  • Uniprot Accession= Q8IYI6
  • Ensembl Transcript= ENST00000366645.1
  • Uniprot Name= EXOC8
  • Name= Exocyst complex component 8
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 25
GO term GO name GO namespace GO def
GO:0030426 growth cone cellular_component The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic. [GOC:aruk, GOC:bc, ISBN:0815316194, PMID:10082468]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0030198 extracellular matrix organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. [GOC:mah]
GO:0035091 phosphatidylinositol binding molecular_function Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives. [GOC:bf, ISBN:0198506732, PMID:11395417]
GO:0007032 endosome organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes. [GOC:dph, GOC:jl, GOC:mah]
GO:0006887 exocytosis biological_process A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. [GOC:mah, ISBN:0716731363, PMID:22323285]
GO:0071840 cellular component organization or biogenesis biological_process A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. [GOC:mah]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0015031 protein transport biological_process The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
GO:0006893 Golgi to plasma membrane transport biological_process The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. [ISBN:0716731363]
GO:0008104 protein localization biological_process Any process in which a protein is transported to, or maintained in, a specific location. [GOC:ai]
GO:0045229 external encapsulating structure organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. [GOC:ai, GOC:dph, GOC:jl, GOC:mah]
GO:0016043 cellular component organization biological_process A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. [GOC:ai, GOC:jl, GOC:mah]
GO:0034613 cellular protein localization biological_process Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. [GOC:mah]
GO:0031267 small GTPase binding molecular_function Binding to a small monomeric GTPase. [GOC:mah, PMID:27218782]
GO:0031252 cell leading edge cellular_component The area of a motile cell closest to the direction of movement. [GOC:pg]
GO:0009987 cellular process biological_process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators, GOC:isa_complete]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0016241 regulation of macroautophagy biological_process Any process that modulates the frequency, rate or extent of macroautophagy. [GOC:krc]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0048471 perinuclear region of cytoplasm cellular_component Cytoplasm situated near, or occurring around, the nucleus. [GOC:jid]
GO:0022411 cellular component disassembly biological_process A cellular process that results in the breakdown of a cellular component. [GOC:isa_complete]
GO:0043062 extracellular structure organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. [GOC:ai, GOC:dph, GOC:jl, GOC:mah]
GO:0000145 exocyst cellular_component A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. [GOC:cilia, PMID:15292201, PMID:27243008, PMID:9700152]
GO:0005770 late endosome cellular_component A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. [NIF_Subcellular:nlx_subcell_20090702, PMID:11964142, PMID:2557062]