| GO term | GO name | GO namespace | GO def |
| GO:0003677 | DNA binding | molecular_function | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb, GOC:vw] |
| GO:0004527 | exonuclease activity | molecular_function | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. [GOC:mah, ISBN:0198547684] |
| GO:0016788 | hydrolase activity, acting on ester bonds | molecular_function | Catalysis of the hydrolysis of any ester bond. [GOC:jl] |
| GO:0140097 | catalytic activity, acting on DNA | molecular_function | Catalytic activity that acts to modify DNA. [GOC:molecular_function_refactoring, GOC:pdt] |
| GO:0004529 | exodeoxyribonuclease activity | molecular_function | Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule. [GOC:mah, ISBN:0198547684] |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | molecular_function | Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. [GOC:ai, PMID:15952888, Wikipedia:Iron-sulfur_cluster] |
| GO:0016895 | exodeoxyribonuclease activity, producing 5'-phosphomonoesters | molecular_function | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. [GOC:ai] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0004518 | nuclease activity | molecular_function | Catalysis of the hydrolysis of ester linkages within nucleic acids. [ISBN:0198547684] |
| GO:0003824 | catalytic activity | molecular_function | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732] |
| GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0090305 | nucleic acid phosphodiester bond hydrolysis | biological_process | The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis. [GOC:dph, GOC:tb] |
| GO:0016796 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | molecular_function | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. [GOC:mah] |
| GO:0008296 | 3'-5'-exodeoxyribonuclease activity | molecular_function | Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule. [GOC:mah] |
| GO:0036297 | interstrand cross-link repair | biological_process | Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. [GOC:vw, PMID:16464006, PMID:22064477] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0008409 | 5'-3' exonuclease activity | molecular_function | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end. [GOC:ai] |
| GO:0008408 | 3'-5' exonuclease activity | molecular_function | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. [GOC:ai] |
| GO:0004536 | deoxyribonuclease activity | molecular_function | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. [GOC:mah, ISBN:0198547684] |
| GO:0016787 | hydrolase activity | molecular_function | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. [ISBN:0198506732] |