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DDOST_ENST00000375048 ,DDOST ,P39656
  • Uniprot Accession= P39656
  • Ensembl Transcript= ENST00000375048.7
  • Uniprot Name= DDOST
  • Name= Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 25
GO term GO name GO namespace GO def
GO:0008250 oligosaccharyltransferase complex cellular_component A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected. [ISBN:0879695595, PMID:15835887]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0005789 endoplasmic reticulum membrane cellular_component The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah]
GO:0006486 protein glycosylation biological_process A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. [GOC:curators, GOC:pr]
GO:0005783 endoplasmic reticulum cellular_component The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732]
GO:0031647 regulation of protein stability biological_process Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation. [GOC:dph, GOC:mah, GOC:tb]
GO:0050790 regulation of catalytic activity biological_process Any process that modulates the activity of an enzyme. [GOC:ai, GOC:ebc, GOC:vw]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0043231 intracellular membrane-bounded organelle cellular_component Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators]
GO:0030659 cytoplasmic vesicle membrane cellular_component The lipid bilayer surrounding a cytoplasmic vesicle. [GOC:mah]
GO:0016021 integral component of membrane cellular_component The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators]
GO:0030667 secretory granule membrane cellular_component The lipid bilayer surrounding a secretory granule. [GOC:mah]
GO:0031090 organelle membrane cellular_component A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. [GOC:dos, GOC:mah]
GO:0018279 protein N-linked glycosylation via asparagine biological_process The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification. [GOC:jsg, RESID:AA0151, RESID:AA0420, RESID:AA0421]
GO:0012506 vesicle membrane cellular_component The lipid bilayer surrounding any membrane-bounded vesicle in the cell. [GOC:mah, GOC:vesicle]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0005774 vacuolar membrane cellular_component The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. [GOC:ai]
GO:0008047 enzyme activator activity molecular_function Binds to and increases the activity of an enzyme. [GOC:dph, GOC:mah, GOC:tb]
GO:0098588 bounding membrane of organelle cellular_component The lipid bilayer that forms the outer-most layer of an organelle. [GOC:dos]
GO:0098852 lytic vacuole membrane cellular_component The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell. [GOC:dos]
GO:0006487 protein N-linked glycosylation biological_process A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. [GOC:pr, RESID:AA0151, RESID:AA0156, RESID:AA0327]
GO:0034097 response to cytokine biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. [GOC:sl]
GO:0042110 T cell activation biological_process The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. [GOC:mgi_curators, ISBN:0781735149]
GO:0005765 lysosomal membrane cellular_component The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai]
GO:0110165 cellular anatomical entity cellular_component A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. [GOC:kmv]