GO term | GO name | GO namespace | GO def |
GO:0042277 | peptide binding | molecular_function | Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds. [GOC:jl] |
GO:0002699 | positive regulation of immune effector process | biological_process | Any process that activates or increases the frequency, rate, or extent of an immune effector process. [GOC:add] |
GO:0006955 | immune response | biological_process | Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. [GO_REF:0000022, GOC:add] |
GO:0050789 | regulation of biological process | biological_process | Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:ai, GOC:go_curators] |
GO:0002708 | positive regulation of lymphocyte mediated immunity | biological_process | Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. [GOC:add] |
GO:0005615 | extracellular space | cellular_component | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684] |
GO:0019882 | antigen processing and presentation | biological_process | The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] |
GO:0009897 | external side of plasma membrane | cellular_component | The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. [GOC:dos, GOC:tb] |
GO:0002682 | regulation of immune system process | biological_process | Any process that modulates the frequency, rate, or extent of an immune system process. [GOC:add] |
GO:0005887 | integral component of plasma membrane | cellular_component | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators] |
GO:0009605 | response to external stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. [GOC:hb] |
GO:0005764 | lysosome | cellular_component | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. [GOC:mah, ISBN:0198506732] |
GO:0022610 | biological adhesion | biological_process | The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions. [GOC:isa_complete] |
GO:0002706 | regulation of lymphocyte mediated immunity | biological_process | Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. [GOC:add] |
GO:0009617 | response to bacterium | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. [GOC:hb] |
GO:0045089 | positive regulation of innate immune response | biological_process | Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. [GOC:ebc] |
GO:0042393 | histone binding | molecular_function | Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity. [GOC:jl] |
GO:0048522 | positive regulation of cellular process | biological_process | Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid] |
GO:0016323 | basolateral plasma membrane | cellular_component | The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators] |
GO:0009986 | cell surface | cellular_component | The external part of the cell wall and/or plasma membrane. [GOC:jl, GOC:mtg_sensu, GOC:sm] |
GO:0050794 | regulation of cellular process | biological_process | Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators] |
GO:0051606 | detection of stimulus | biological_process | The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. [GOC:add, GOC:ai, GOC:dph, GOC:mah] |
GO:0048518 | positive regulation of biological process | biological_process | Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid] |
GO:0009987 | cellular process | biological_process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators, GOC:isa_complete] |
GO:0008289 | lipid binding | molecular_function | Binding to a lipid. [GOC:ai] |
GO:0002819 | regulation of adaptive immune response | biological_process | Any process that modulates the frequency, rate, or extent of an adaptive immune response. [GOC:add] |
GO:0044419 | biological process involved in interspecies interaction between organisms | biological_process | Any process evolved to enable an interaction with an organism of a different species. [GOC:cc] |
GO:0002684 | positive regulation of immune system process | biological_process | Any process that activates or increases the frequency, rate, or extent of an immune system process. [GOC:add] |
GO:0050839 | cell adhesion molecule binding | molecular_function | Binding to a cell adhesion molecule. [GOC:ai] |
GO:0009607 | response to biotic stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. [GOC:hb] |
GO:0048583 | regulation of response to stimulus | biological_process | Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid] |
GO:0007155 | cell adhesion | biological_process | The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [GOC:hb, GOC:pf] |
GO:0002376 | immune system process | biological_process | Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. [GO_REF:0000022, GOC:add] |
GO:0002821 | positive regulation of adaptive immune response | biological_process | Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. [GOC:add] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0045087 | innate immune response | biological_process | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu] |
GO:0005765 | lysosomal membrane | cellular_component | The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai] |
GO:0048584 | positive regulation of response to stimulus | biological_process | Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0050896 | response to stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. [GOC:ai, GOC:bf] |
GO:0098609 | cell-cell adhesion | biological_process | The attachment of one cell to another cell via adhesion molecules. [GOC:dos] |
GO:0002703 | regulation of leukocyte mediated immunity | biological_process | Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. [GOC:add] |
GO:0051707 | response to other organism | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. [GOC:ai] |
GO:0005789 | endoplasmic reticulum membrane | cellular_component | The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah] |
GO:0002697 | regulation of immune effector process | biological_process | Any process that modulates the frequency, rate, or extent of an immune effector process. [GOC:add] |
GO:0065007 | biological regulation | biological_process | Any process that modulates a measurable attribute of any biological process, quality or function. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] |
GO:0033218 | amide binding | molecular_function | Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. [GOC:mah] |
GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
GO:0010008 | endosome membrane | cellular_component | The lipid bilayer surrounding an endosome. [GOC:mah] |
GO:0042102 | positive regulation of T cell proliferation | biological_process | Any process that activates or increases the rate or extent of T cell proliferation. [GOC:ai] |
GO:0005783 | endoplasmic reticulum | cellular_component | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732] |
GO:0002705 | positive regulation of leukocyte mediated immunity | biological_process | Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. [GOC:add] |
GO:0043207 | response to external biotic stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. [GOC:go_curators] |
GO:0050778 | positive regulation of immune response | biological_process | Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. [GOC:ai] |
GO:0050776 | regulation of immune response | biological_process | Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. [GOC:ai] |
GO:0005488 | binding | molecular_function | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732] |