Intrinsically disordered proteins (IDPs) play important roles in a wide range of biological processes and have been associated with various diseases, including cancer. In the last few years, cancer genome projects have systematically collected genetic variations underlying multiple cancer types. In parallel, the number and different types of disordered proteins characterized by experimental methods have also significantly increased. Nevertheless, the role of IDPs in various types of cancer is still not well understood. DisCanVis aids the interpretation of observed mutations by providing a visualization tool where genome level information is combined with information about the structural and functional properties of proteins.
Search ProteinInspect individual proteins, collect examples with existing annotations of protein disorder and associated function or to discover currently uncharacterized examples with likely disease relevance!
Search ProteinStart exploring the database by checking out one of these three examples!